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MAGEB2 is a member of the MAGEB gene family. Zusätzlich bieten wir Ihnen MAGEB2 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal MAGEB2 Primary Antibody für WB - ABIN4891156
Milutinovic, DAlessio, Detich, Szyf: Valproate induces widespread epigenetic reprogramming which involves demethylation of specific genes. in Carcinogenesis 2007
MAGEB2 can be aberrantly demethylated and expressed in malignant peripheral nerve sheath tumors. Conversely, the gene may not be demethylated in any types of neurofibroma, suggesting that the demethylation does not occur before malignant transformation.
MageB2 counteracts E2F (zeige E2F1 Antikörper) inhibition by ribosomal proteins independently of Mdm2 (zeige MDM2 Antikörper) expression
we identified MAGEB2 as activated by promoter demethylation in HNSCCand demonstrates growth promoting effects in a minimally transformed oral keratinocyte cell line.
Results show that hypertonic culture medium differentially induces the expression of melanoma antigens B1 and B2 (MAGE-B1 (zeige MAGEB1 Antikörper), -B2) in different human tumor cell lines.
This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21.
melanoma antigen family B, 2
, DSS-AHC critical interval MAGE superfamily 6
, DSS/AHC critical interval MAGE superfamily 6
, MAGE XP-2 antigen
, MAGE-B2 antigen
, cancer/testis antigen 3.2
, cancer/testis antigen family 3, member 2
, melanoma-associated antigen B2