anti-Melanoma Antigen Family A, 2 (MAGEA2) Antikörper

MAGEA2 is a member of the MAGEA gene family. Zusätzlich bieten wir Ihnen MAGEA2 Proteine (1) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MAGEA2 17138  
MAGEA2 4101 P43356
MAGEA2    
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Top anti-MAGEA2 Antikörper auf antikoerper-online.de

Showing 10 out of 35 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB <b>WB Suggested Anti-MAGEA2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>Jurkat cell lysate WB Suggested Anti-MAGEA2 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 <br /> Positive Control: Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB The anti-MAGEA2 N-term Antibody (ABIN390106) is used in Western blot to detect MAGEA2 in HL60 lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IHC (p), ELISA Human Testis (formalin-fixed, paraffin-embedded) stained with MAGEA2 antibody ABIN214688 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Maus Unkonjugiert ELISA, WB MAGEA2 monoclonal antibody (M01), clone 1H4 Western Blot analysis of MAGEA2 expression in Jurkat . Western Blot analysis of MAGEA2 expression in transfected 293T cell line by MAGEA2 monoclonal antibody (M01), clone 1H4.<br><br>Lane 1: MAGEA2 transfected lysate(35 KDa).<br>Lane 2: Non-transfected lysate.<br> 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC, ELISA 0.05 mg Anmelden zum Anzeigen 2 bis 3 Tage
$550.00
Details
Human Kaninchen Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
Details
Human Kaninchen Biotin IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
Details
Human Kaninchen FITC IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
Details

MAGEA2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine)


Human ,
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,
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Cow (Bovine)


Weitere Antikörper gegen MAGEA2 Interaktionspartner

Human Melanoma Antigen Family A, 2 (MAGEA2) Interaktionspartner

  1. Data indicate that melanoma-associated antigen (zeige ZNF654 Antikörper) A2 (MAGEA2)is significantly overexpressed in triple-negative breast cancer (TNBC) tissues and is important for progression of TNBC and may serve as a novel molecular therapeutic target.

  2. suppression of MAGEA2 in lung cancer cells significantly reduced the growth/survival of cancer cells. High-MAGEA2 was identified as an independent prognostic factor in lung adenocarcinoma. Specific inhibition of MAGEA2 may be a promising therapeutic strategy for patients with lung cancer.

  3. Immunohistochemistry using D2-40 monoclonal antibody (MAGE2) and anti-MITF1 increased detection of lymphovascular invasion in primary cutaneous melanoma.

  4. We find that MAGE-A2 interacts with MDM2 (zeige MDM2 Antikörper) via the N-terminal p53 (zeige TP53 Antikörper)-binding pocket and the RING finger (zeige PCGF1 Antikörper) domain of MDM2 (zeige MDM2 Antikörper) that is required for homo/hetero-dimerization and for E2 ligase interaction.

  5. Consistent with increased cell death, the induced loss of MAGEA2 expression correlated with increased caspase 3 (zeige CASP3 Antikörper)/7 activity, BCL2 (zeige BCL2 Antikörper)/BAX (zeige BAX Antikörper) ratio and TUNEL signal.

  6. MAGEA2 has a critical role in the development of tamoxifen-resistant breast cancer

  7. MageA2 interferes with p53 (zeige TP53 Antikörper) acetylation at PML (zeige PML Antikörper)-nuclear bodies (NBs (zeige NBN Antikörper)) and with PMLIV-dependent activation of p53 (zeige TP53 Antikörper).

  8. Report MAGEA1 (zeige MAGEA1 Antikörper)-A6 expression in sputum suggests presence of lung cancer cells or precancerous cells.

  9. These data suggest that MAGEA2 is differentially expressed in HNSCC and functions, in part, through the p53 (zeige TP53 Antikörper) pathway by increasing cellular proliferation and abrogating cell cycle arrest.

  10. MAGE-A2 targets p53 (zeige TP53 Antikörper) transactivation function through histone deacetylase (zeige HDAC1 Antikörper) recruitment

MAGEA2 Antigen-Profil

Protein Überblick

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This gene has two identical copies at different loci. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.

Genbezeichner und Symbole assoziert mit MAGEA2

  • melanoma antigen, family A, 2 (Magea2) Antikörper
  • melanoma-associated antigen 2 (LOC706218) Antikörper
  • MAGE family member A2 (MAGEA2) Antikörper
  • CT1.2 Antikörper
  • Mage-a2 Antikörper
  • MAGE2 Antikörper
  • MAGEA2 Antikörper
  • MAGEA2A Antikörper

Bezeichner auf Proteinebene für MAGEA2

melanoma antigen family A, 2 , MAGE-2 antigen , cancer/testis antigen 1.2 , cancer/testis antigen family 1, member 2 , melanoma antigen 2 , melanoma-associated antigen 2

GENE ID SPEZIES
17138 Mus musculus
706218 Macaca mulatta
4101 Homo sapiens
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