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MDM1 encodes a nuclear protein similar to the mouse double minute 1 protein.
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Authorse propose that MDM1 is a negative regulator of centriole duplication and that its function is mediated through microtubule binding.
Not associated with age-related retinal degeneration.
Depletion of the Mdm1 transcript may underlie the mechanism leading to late-onset progressive retinal degeneration in arrd2 mice.
This gene encodes a nuclear protein similar to the mouse double minute 1 protein. The mouse gene is located in double minute (DM) chromatin particles, is amplified in the mouse transformed 3T3 cell line, and the encoded protein is able to bind to p53. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
nuclear protein MDM1
, Mdm4, transformed 3T3 cell double minute 1, p53 binding protein
, nuclear protein double minute 1
, Mitochondrial deafness modifier 1
, transformed mouse 3T3 cell double minute 1
, Mdm4, transformed 3T3 cell double minute 1, p53 binding protein, homolog
, double minute 1
, mdm4 transformed 3T3 cell double minute 1 protein