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MMP19 encodes a member of a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Zusätzlich bieten wir Ihnen MMP19 Kits (21) und MMP19 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal MMP19 Primary Antibody für ICC, IF - ABIN269681
Sena, Mariani, Marzona, Benincasa, Ponz de Leon, Palumbo, Roncucci: Matrix metalloproteinases 15 and 19 are stromal regulators of colorectal cancer development from the early stages. in International journal of oncology 2012
Levels of matrix metalloproteinases MMP-19 and MMP-20 expression are significantly increased in pancreatic ductal adenocarcinoma (PDAC).
transcriptional target (zeige ESR2 Antikörper) of ligand-bound activated (zeige ESR2 Antikörper) estrogen receptor beta (zeige PSG1 Antikörper)acting on a specificity protein-1 binding site
the downregulation of MMP19 following respiratory syncytial virus infection may be associated with the development of airway hyperresponsiveness.
Loss of NDRG2 (zeige NDRG2 Antikörper) induced the expression of matrix metalloproteinase-19 (MMP-19), which regulated the expression of Slug at the transcriptional level in the epithelial-mesenchymal transition of gallbladder carcinoma cells.
Triplication of an enhancer may lead to overexpression of MMP19 in the optic nerve that causes cavitary optic disc anomaly.
the intima+media of IPAH vessels, collagens (COL4A5 (zeige COL4a5 Antikörper), COL14A1 (zeige COL14A1 Antikörper), and COL18A1 (zeige COL18A1 Antikörper)), matrix metalloproteinase (MMP) 19, and a disintegrin and metalloprotease (ADAM) 33 (zeige ADAM33 Antikörper) were higher expressed, whereas MMP10 (zeige MMP10 Antikörper), ADAM17 (zeige ADAM17 Antikörper), TIMP1 (zeige TIMP1 Antikörper), and TIMP3 (zeige TIMP3 Antikörper) were less abundant.
The expression of MMP-19 in the main forms of gastrointestinal diseases, was analysed.
Matrix metalloproteinase-19 in lung epithelial cells stimulates proliferation and cell migration. Read More: http://www.atsjournals.org/doi/full/10.1164/rccm.201310-1903OC
ASNS (zeige ASNS Antikörper) and MMP19, along with eIF3a (zeige EIF6 Antikörper), are the sensitivity factors for cisplatin treatment and may serve as potential candidate molecular markers for predicting cisplatin sensitivity of advanced nasopharyngeal carcinoma.
These findings indicated for the first time that the co-expression of MMP-14 (zeige MMP14 Antikörper) and MMP-19 is significantly correlated with prognosis in glioma patients
this study shows that MMP-19 deficiency causes aggravation of colitis due to defects in innate immune cell function
Estrogen receptor beta (zeige ESR2 Antikörper) target gene, where ERbeta (zeige ESR2 Antikörper) requires a specific Sp1 (zeige SP1 Antikörper) site on the MMP-19 promoter to mediate ligand dependent transcription
These findings suggest that, in lung fibroblasts, MMP-19 has strong regulatory effects on the synthesis of key ECM (zeige MMRN1 Antikörper) components, on fibroblast to myofibroblast differentiation, and in migration and proliferation.
MMP-19-deficiency improves the development of hepatic fibrosis through the diminished replacement of physiological extracellular matrix with fibrotic deposits in the beginning of the injury
In WT mice, PTGS2 (zeige PTGS2 Antikörper) was significantly increased in bronchoalveolar lavage and lung tissues after bleomycin-induced fibrosis, but not in Mmp19-/- mice. Inhibition of Mmp-19 by siRNA resulted in inhibition of Ptgs2 (zeige PTGS2 Antikörper) at mRNA and protein levels.
An osteosarcoma zebrafish model implicates Mmp-19 and Ets-1 (zeige ETS1 Antikörper) as well as reduced host immune response in angiogenesis and migration.
Matrix metalloproteinase-19 deficiency promotes tenascin-C (zeige TNC Antikörper) accumulation and allergen-induced airway inflammation.
Mmp19-null mice develop a diet-induced obesity due to adipocyte hypertrophy and exhibit decreased susceptibility to skin tumors induced by chemical carcinogens.
Based on the phenotype of MMP19-deficient mice we propose that MMP19 is an important factor in cutaneous immune responses and influences the development of T cells
This gene encodes a member of a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded protein is secreted as an inactive proprotein, which is activated upon cleavage by extracellular proteases. Alternative splicing results in multiple transcript variants for this gene.
matrix metallopeptidase 19
, matrix metalloproteinase-18
, matrix metalloproteinase RASI
, matrix metalloproteinase-19
, matrix metalloproteinase-beta19
, matrix metalloproteinase 19