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MATN2 encodes a member of the von Willebrand factor A domain containing protein family. Zusätzlich bieten wir Ihnen Matrilin 2 Antikörper (53) und Matrilin 2 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.
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findings showed that YopK binds to the cell surface-exposed endogenous MATN2 and that purified YopK protein strongly inhibits the bacterial adherence to HeLa cells
Data show that the mRNA and protein levels of matrilin-2 were increased after irradiation treatment in both mouse lung tissue and human pulmonary alveolar epithelial cells (HPAEpiC).
Taken together, our results showed that high-glucose-induced Matrilin-2 expression that was mediated by the TGF-beta1/Smad3 signaling pathway might play a role in Diabetic nephropathy (DN) pathogenesis and our finding provided a potential diagnostic and/or therapeutic target for DN.
Matrilin-2 induces post-burn inflammatory responses as an endogenous danger signal, partly through a TLR4-mediated mechanism
matrilin-2, a filament-forming protein widely distributed in extracellular matrices.
matrilin-2 is expressed in normal skin by keratinocytes and fibroblasts and may thus contribute to cutaneous homeostasis.
study of interactions by which matrilin-2 can be integrated into extracellular filamentous networks
These results suggest that matrilin-2 may be a specific and clinically useful biomarker for discriminating between indolent and clinically aggressive pilocytic astrocytoma.
DeltaNp63/BMP-7 signaling pathway modulates wound healing process through the regulation of matrilin-2.
data indicate matrilin-2 is a novel basement membrane component in the liver, synthesized during sinusoidal "capillarization" in cirrhosis & in hepatocellular carcinoma
Matn2 functions as a tumor suppressor in hepatocarcinogenesis, and in this process activation of EGFR together with that of Erk1/2, as well as inactivation of GSK-3beta, play strategic roles.
The absence of matrilin-2 has no effect on hepatic stellate cell activation and regression kinetics, synthetic activity, proliferative capacity, motility, or HSC apoptosis.
MATN2 is a deleterious endogenous neuroaxonal injury response signal that activates innate immune cells.
Matrilin-2 may play an important role in the communication of matrix to matrix and matrix to cells and will be used as a potential biomarker in the early stage of osteoarthritis of articular cartilage.
Expression of matrilin-2 during maturation of mouse skeletal tissues
Matrilin-2 null mice show no gross abnormalities during embryonic or adult development, are fertile, and have a normal lifespan.
matrilin 2 is a permissive substrate for axonal growth and cell migration, and that it is required for successful nerve regeneration.
This gene encodes a member of the von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains five von Willebrand factor A domains. The specific function of this gene has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.