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Catalyzes the first committed step in the biosynthesis of complex N-glycans.
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Man2a2 null spermatogenic cells fail to adhere to Sertoli cells and are prematurely released from the testis to epididymis
Data show that either alpha-Mannosidase II (zeige MAN2A1 Proteine) or IIX can biochemically compensate for the deficiency of the other in vivo, and either of two is required for late embryonic and early postnatal development.
Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans\; the final hydrolytic step in the N-glycan maturation pathway.
, mannosidase, alpha, class 2A, member 2
, alpha mannosidase IIx
, alpha-mannosidase IIx
, mannosidase alpha class 2A member 2
, mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase
, MAN IIx
, mannosidase, alpha type II-X
, manosidase, alpha-, type II, isozyme X