Mannosidase, Alpha, Class 1B, Member 1 Proteine (MAN1B1)

MAN1B1 encodes an enzyme belonging to the glycosyl hydrolase 47 family. Zusätzlich bieten wir Ihnen MAN1B1 Antikörper (21) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
MAN1B1 11253 Q9UKM7
MAN1B1 227619 A2AJ15
MAN1B1 499751 B2GUY0
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Top MAN1B1 Proteine auf antikoerper-online.de

Showing 9 out of 9 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 60 bis 65 Tage
$10,888.92
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 60 bis 65 Tage
$7,639.51
Details
Human Cells Human His tag   50 μg Anmelden zum Anzeigen 4 Days
$442.75
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Human Cells Human His tag   10 μg Anmelden zum Anzeigen 15 bis 16 Tage
$225.00
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,016.67
Details
HEK-293 Cells Human His tag   10 μg Anmelden zum Anzeigen 8 bis 11 Tage
$227.70
Details

MAN1B1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, ,
Mouse (Murine) ,
,
Rat (Rattus)

Weitere Proteine zu Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1) Interaktionspartnern

Human Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1) Interaktionspartner

  1. Results show that MAN1B1 expression was higher in bladder cancer (BC) tissues than those in normal tissues. Its overexpression was associated with poor prognosis. Furthermore, MAN1B1 seems to act as an oncogene (zeige RAB1A Proteine) in BC, which improved the likelihood of MAN1B1 taking on a promising prognostic biomarker.

  2. The two genetic associations with severe liver disease that had been suspected previously (one SNP for SERPINA1 (zeige SERPINA1 Proteine) and another for MAN1B1) were not confirmed in our cohort. For MAN1B1, four major haplotypes were identified but the prevalence of PHT did not significantly differ between them.

  3. in the bound substrate complex, hydrophobic stacking interactions between Trp (zeige TBPL1 Proteine) residues and the glycan core anchor the base of the glycan structure to the enzyme cleft

  4. MAN1B1 defective congenital disorder of glycosylation is reviewed.

  5. Data show that HIV-1 env (zeige ERVW-1 Proteine) protein interacts with alpha-mannosidases ERManI (MAN1B1) and initiates endoplasmic reticulum (ER)-associated protein degradation (ERAD) pathway degradation process.

  6. The properties of ERMAN1 enable rapid selection of endoplasmic reticulum-associated degradation substrates in the endoplasmic reticulum.ERMAN1 digests mono-, di- and tri (zeige VANGL2 Proteine)-glucosylated N-glycans.

  7. we linked mutations in MAN1B1 to a Golgi glycosylation disorder. Additionally, our results support the recent findings on MAN1B1 localization

  8. MAN1B1 deficiency appeared to be a frequent cause in our cohort of patients with unsolved congenital disorder of glycosylation type II.

  9. A novel post-transcriptional regulatory mechanism for ERManI via miR (zeige MLXIP Proteine)-125b and this molecule contributes to the regulation of carcinogenesis in hepatocellular carcinoma.

  10. ERManI and gamma-COP contribute to a golgi-based quality control module that facilitates the retrieval of captured ERAD substrates back to the endoplasmic reticulum.

MAN1B1 Protein Überblick

Protein Überblick

This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11.

Genbezeichner und Symbole assoziert mit MAN1B1

  • mannosidase alpha class 1B member 1 (MAN1B1)
  • mannosidase, alpha, class 1B, member 1 L homeolog (man1b1.L)
  • endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (LOC480667)
  • mannosidase, alpha, class 1B, member 1 (man1b1)
  • mannosidase, alpha, class 1B, member 1 (Man1b1)
  • E430019H13Rik Protein
  • ERMan1 Protein
  • Gm108 Protein
  • MAN1B1 Protein
  • MANA-ER Protein
  • MRT15 Protein
  • RGD1563595 Protein

Bezeichner auf Proteinebene für MAN1B1

mannosidase, alpha, class 1B, member 1 , alpha 1,2-mannosidase , ER alpha 1,2-mannosidase , Man9GlcNAc2-specific processing alpha-mannosidase , endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase , endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 1 , ER alpha-1,2-mannosidase , ER mannosidase 1 , man9GlcNAc2-specific-processing alpha-mannosidase

GENE ID SPEZIES
417296 Gallus gallus
447291 Xenopus laevis
473099 Pan troglodytes
480667 Canis lupus familiaris
100145194 Xenopus (Silurana) tropicalis
11253 Homo sapiens
227619 Mus musculus
499751 Rattus norvegicus
Ausgewählte Anbieter für MAN1B1 Proteine (MAN1B1)
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