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The protein encoded by MCTS1 is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Zusätzlich bieten wir Ihnen Malignant T Cell Amplified Sequence 1 Proteine (12) und Malignant T Cell Amplified Sequence 1 Kits (11) und viele weitere Produktgruppen zu diesem Protein an.
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Mouse (Murine) Polyclonal MCTS1 Primary Antibody für IHC - ABIN966547
Carpenter, Poole, Halestrap: Cloning and sequencing of the monocarboxylate transporter from mouse Ehrlich Lettré tumour cell confirms its identity as MCT1 and demonstrates that glycosylation is not required for MCT1 function. in Biochimica et biophysica acta 1996
Show all 6 Pubmed References
Human Polyclonal MCTS1 Primary Antibody für WB - ABIN152954
Kumar, Kant, Singh et al.: Antitumor and chemosensitizing action of dichloroacetate implicates modulation of tumor microenvironment: a role of reorganized glucose metabolism, cell survival regulation and macrophage ... in Toxicology and applied pharmacology 2013
Human Polyclonal MCTS1 Primary Antibody für WB - ABIN4891880
Haas, Ngo, Li, Schleich, Qu, Vanyai, Cullen, Cardona-Alberich, Gladwyn-Ng, Pagnamenta, Taylor, Stewart, Kini, Duncan, Teleman, Keays, Heng: De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation. in Cell reports 2016
PKC (zeige PRRT2 Antikörper) inhibitor sotrastaurin induced cell apoptosis and cell cycle arrest in DLBCL cells potentially through regulating the expression of MCT-1 (zeige CMA1 Antikörper)
DENR (zeige DENR Antikörper) binds to the P-site of the 40S ribosomal subunit and together with MCTS1 forms a tRNA binding surface and interferes with eIF1 (zeige EIF1 Antikörper)/eIF2 (zeige EIF2S1 Antikörper)/eIF3 (zeige EIF3A Antikörper) binding, thus operating in post-termination ribosome recycling and translation re-initiation
Reinitiation complexes involving initiation factors eIF2D (zeige EIF2D Antikörper), MCT-1 (zeige CMA1 Antikörper), and DENR (zeige DENR Antikörper) controls the translation of a large fraction of mammalian cellular mRNAs.
Overexpression of MCT1 (zeige CMA1 Antikörper) is associated with gliomas.
MCT-1 (zeige CMA1 Antikörper) is a new centrosomal-associated oncoprotein, and that it plays a novel role in the regulation of mitosis signifies its important function in the process of tumorigenesis.
The present study indicates possible involvement of a protein kinase (zeige CDK7 Antikörper) (PK)C- and PKA-mediated pathway associated with expression of MCT1 (zeige CMA1 Antikörper) and lactate transport in rhabdomyosarcoma cells.
The oppositions between MCT-1 (zeige CMA1 Antikörper) and p53 (zeige TP53 Antikörper) are firstly confirmed at multistage processes that include transcription control, mRNA metabolism, and protein expression
The result suggest that co-expression of CD147 and MCT1 (zeige CMA1 Antikörper)/MCT4 (zeige SLC16A4 Antikörper) is related to drug resistance during EOC metastasis and could be useful therapeutic targets to prevent the development of incurable, recurrent and drug resistance EOC.
Results describe the expression and purification of MCT-1 (zeige CMA1 Antikörper) in insect cells using a baculovirus expression system.
tumor cell lines overexpressing MCT-1 (zeige CMA1 Antikörper) exhibited increased growth rates and displayed increased protection against apoptosis induced by serum starvation
Data suggest that expression of MCT1 in intestinal mucosa can be altered by diet; here, expression of MCT1 is down-regulated in colonic mucosa by high-protein diet and appears to be linked to fermentation of dietary proteins by intestinal microbes.
MCT1-mRNA showed a higher expression in the ileum; feeding inulin-coated butyrate resulted in an increased ileal surface; delivery of butyrate to the colon requires a more resistant inulin-coating.
The protein encoded by this gene is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants have been found for this gene.
malignant T cell-amplified sequence 1
, malignant T-cell-amplified sequence 1
, multiple copies T-cell malignancies
, multiple copies T-cell malignancies 1
, malignant T cell amplified sequence 1
, Malignant T cell amplified sequence 1-A
, malignant T cell-amplified sequence 1-A
, malignant T-cell-amplified sequence 1-A