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MAB21L1 is similar to the MAB-21 cell fate-determining gene found in C.
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Despite the absence of conserved non-coding elements, a 4.9-kb mab21l2 (zeige MAB21L2 Proteine) promoter is sufficient to recapitulate expression in tissues unique to mab21l1 or mab21l2 (zeige MAB21L2 Proteine).
Data revealed that expression of DNA binding inhibitor 3, early B cell factor 2, Ebf3, Iroquois related homeobox 1, Kruppel-like factor 7 , mab-21-like 1 , fatty acid binding protein 7 and stathmin-like 4,were enriched in the diencephalon of zebrafish.
offer a structure-based explanation for the effects of MAB21L2 (zeige MAB21L2 Proteine) mutations in patients with eye malformations
mab21 gene family members, mab21l1 and mab21l2 (zeige MAB21L2 Proteine), play important roles in regulating eye development. [review]
We hypothesize that MAB21L1 haploinsufficiency cause a previously undescribed syndrome with scrotal agenesis, ophthalmological anomalies, facial dysmorphism and gross psychomotor delay as remarkable hallmarks.
MEF is involved in PTH (zeige PTH Proteine) suppression of osteoblasts through activating the MKK4 (zeige MAP2K4 Proteine)/JNK1 (zeige MAPK8 Proteine) pathway and subsequently up-regulating Mab21l1 expression.
This gene is similar to the MAB-21 cell fate-determining gene found in C. elegans. It may be involved in eye and cerebellum development, and it has been proposed that expansion of a trinucleotide repeat region in the 5' UTR may play a role in a variety of psychiatric disorders.
protein mab-21-like 1
, cell fate determination protein
, mab-21-like protein 1