MOK Protein Kinase Proteine (MOK)

Human MOK Protein Kinase (MOK) Interaktionspartner

1. our results suggest MOK promoter hypomethylation is a common event and contributes to MOK overexpression in acute myeloid leukemia

2. The findings indicate a statistically significant association of p.Gly82Ser polymorphism in RAGE with DR in T2DM patients.

3. the expressions of ICK/MAK/MOK proteins in the intestinal tract can be differentially and dynamically regulated, implicating a significant functional diversity within this group of protein kinases.

4. Our results suggest that RAGE may be important in tumor invasion and could be a potential predictor for the prognosis of hepatocellular carcinoma patients.

5. PBMNC from type 2 diabetics were more sensitive to innate immune stimulation with LPS and monoclonal agonist anti-TLR4 than were cells from ND. The actions of LPS, anti-TLR4 and anti-RAGE potentiated the production of IL-6 and TNF-alpha in both groups.

6. The RAGE pathway may play an important role in STAT3 induction in glioma-associated macrophages and microglia, a process that may be mediated through S100B.

7. RAGE was demonstrated in all 8 yolk sac tumors and 21 of 26 embryonal carcinomas. In yolk sac tumors, RAGE reactivity was diffusely present throughout the tumors. In embryonal carcinomas, RAGE was identified only in yolk sac components

8. identification of MOK, a member of the mitogen-activated protein kinase superfamily, as one of the genes induced by a caudal-related homeobox transcription factor, Cdx2

9. May provide suitable targets for immunotherapy of renal cell carcinoma.

10. Compared RAGE and PAX-2 staining in metastatic clear renal cell carcinoma.

11. POLL is under genetic selection in Sub-Saharan African populations.

Mouse (Murine) MOK Protein Kinase (MOK) Interaktionspartner

1. This provides new insight into the immune phenotype, mechanisms, and signaling pathways that operate in microglial neurotoxic activation in amyotrophic lateral sclerosis.

2. the expressions of ICK/MAK/MOK proteins in the intestinal tract can be differentially and dynamically regulated, implicating a significant functional diversity within this group of protein kinases.

3. identification of MOK, a member of the mitogen-activated protein kinase superfamily, as one of the genes induced by a caudal-related homeobox transcription factor, Cdx2

4. RAGE inactivation inhibits the atherosclerosis through reducing oxLDL-induced pro-inflammatory responses and oxidative stress in hyperlipidaemia.

5. Suppression of Egr-1 may contribute to the protective mechanisms underlying the beneficial impact of RAGE blockade or deletion in hepatic ischemia/reperfusion injury.