anti-MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) (MOBKL1B) Antikörper

Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. Zusätzlich bieten wir Ihnen MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) Proteine (13) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MOBKL1B 55233 Q9H8S9
MOBKL1B 232157 Q921Y0
MOBKL1B 297387 Q3T1J9
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Top anti-MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) Antikörper auf antikoerper-online.de

Showing 10 out of 84 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-MOB1A Antibody Titration: 1.0 ug/ml Positive Control: Jurkat Whole Cell MOB1A is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-MOB1A Antibody Titration: 1.0 ug/ml Positive Control: Fetal Heart 100 μL 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB ABIN6270241 at 1/100 staining rat heart tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. ABIN6270241 at 1/100 staining rat lung tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL 11 bis 12 Tage
$450.00
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB ABIN6270239 at 1/100 staining mouse heart tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. ABIN6270239 at 1/100 staining mouse kidney tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL 11 bis 12 Tage
$450.00
Details
Human Kaninchen Unkonjugiert EIA, FACS, WB Flow cytometric analysis of 293 cells using MOBKL1B Antibody (N-term) Cat.-No AP52718PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Western blot analysis of MOBKL1B (arrow) using MOBKL1B Antibody (N-term) Cat.-No AP52718PU-N. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MOBKL1B gene. 0.4 mL 6 bis 8 Tage
$484.00
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB 100 μL Verfügbar
$363.46
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of MOBKL1B antibody (C-term) in A2058 cell line lysates (35ug/lane). MOBKL1B (arrow) was detected using the purified Pab. 0.4 mL 6 bis 8 Tage
$484.00
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of MOB1A in lysates of 293, using MOB1A Antibody(ABIN6271089). 100 μL 11 bis 12 Tage
$450.00
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of MOBKL1B antibody in A2058 cell line lysates (35ug/lane) MOBKL1B Antibody IHC analysis in formalin fixed and paraffin embedded human Prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL 2 bis 3 Tage
$515.63
Details
Human Maus Unkonjugiert Fig. 1. Figure 1:Black line: Control Antigen (100 ng)Purple line: Antigen (10ng) 100 μg 11 bis 16 Tage
$469.05
Details

Weitere Antikörper gegen MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) Interaktionspartner

Xenopus laevis MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) (MOBKL1B) Interaktionspartner

  1. Data report the solution structure of the Mob1 protein from Xenopus laevis solved by heteronuclear multidimensional NMR.

Zebrafish MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) (MOBKL1B) Interaktionspartner

  1. mats1 plays a critical role in regulating cell proliferation and apoptosis during early development in zebrafish[mats1]

Human MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) (MOBKL1B) Interaktionspartner

  1. validated the functional importance of an identified interaction network by characterizing a distinct novel interaction between PTPN5 and Mob1a.

  2. Through a comprehensive set of biochemical, biophysical, mutational and structural studies, we quantitatively assess how phosphorylation of MOB1A regulates its interaction with both MST kinases and LATS/NDR family kinases in vitro.

  3. In this study, we investigated the mechanisms behind the recruitment of MST1 and MST2 kinases to MOB1, which facilitate signal transmission in the Hippo pathway by bringing the MST1 and MST2 kinases in close vicinity to their substrates, the LATS family kinases.

  4. MOB1 binds differently to the NDR2 and LATS1 kinases.MOB1 interaction with Hippo and MST protein is not essential for development and tissue growth control.

  5. No relationship has been found between the MOBKL1B-NS5A interaction and hepatitis C virus replication.

  6. The RING ligase praja2 ubiquitylates and degrades Mob, a core component of NDR/LATS kinase and a positive regulator of the tumour-suppressor Hippo cascade.

  7. Mob1A and Mob1B are needed for cell abscission and centriole re-joining after telophase and cytokinesis.

  8. Results suggest that Mob1 and the other mammalian orthologues of the mitotic exit network regulate mitotic progression by facilitating the timely mobilization of the chromosomal passenger complex to the spindle midzone.

  9. hMOB1A and hMOB1B are 2 LATS-binding proteins that may function as tumor suppressors in human cancer cells.

  10. Mats1 can rescue the lethality associated with loss of Mats function in Drosophila; As Mats1 is mutated in human tumors, Mats-mediated growth inhibition and tumor suppression is likely conserved in humans

  11. MATS1 mRNA expression is suppressed in tumor tissue and its low expression is associated with tumor growth, invasion and metastasis of colorectal cancer

Mouse (Murine) MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) (MOBKL1B) Interaktionspartner

  1. T-cell-specific double knockout of MOB1A/B in mice reduces the number of naive T cells in both the circulation and secondary lymphoid organs, but leads to an accumulation of CD4(+) CD8(-) and CD4(-) CD8(+) single-positive cells in the thymus.

  2. MOB1A and MOB1B have overlapping functions in skin homeostasis, and exert their roles as tumor suppressors by regulating downstream elements of the Hippo pathway.

MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) (MOBKL1B) Antigen-Profil

Protein Überblick

Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38 and STK38L. Acts cooperatively with STK3/MST2 to activate STK38 (By similarity).

Genbezeichner und Symbole assoziert mit MOBKL1B

  • MOB kinase activator 1A L homeolog (mob1a.L) Antikörper
  • MOB kinase activator 1A (MOB1A) Antikörper
  • MOB kinase activator 1A (mob1a) Antikörper
  • MOB kinase activator 1A pseudogene (LOC712156) Antikörper
  • MOB kinase activator 1A (Mob1a) Antikörper
  • 4022402H07Rik Antikörper
  • C2orf6 Antikörper
  • MATS1 Antikörper
  • MOB1 Antikörper
  • MOB1A Antikörper
  • MOB4B Antikörper
  • Mobk1b Antikörper
  • Mobkl1b Antikörper
  • wu:fv69d04 Antikörper
  • zgc:56189 Antikörper

Bezeichner auf Proteinebene für MOBKL1B

MOB1, Mps One Binder kinase activator-like 1B , Mob4B protein , mps one binder kinase activator-like 1B , MOB1, Mps One Binder kinase activator-like 1B (yeast) , mats1 , mobk1b , Mps one binder kinase activator-like 1B , mob1 homolog 1B , MOB1 Mps One Binder homolog A , mob1 alpha

GENE ID SPEZIES
398675 Xenopus laevis
459544 Pan troglodytes
549780 Xenopus (Silurana) tropicalis
612924 Canis lupus familiaris
614611 Bos taurus
712156 Macaca mulatta
100005014 Danio rerio
100172677 Pongo abelii
55233 Homo sapiens
232157 Mus musculus
297387 Rattus norvegicus
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