MMS22-Like, DNA Repair Protein (MMS22L) ELISA Kits

Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. Zusätzlich bieten wir Ihnen und und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Ratte MMS22L MMS22L 313108  
Anti-Human MMS22L MMS22L 253714 Q6ZRQ5
Anti-Maus MMS22L MMS22L 212377 B1AUR6
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Weitere ELISA Kits für MMS22-Like, DNA Repair Protein Interaktionspartner

Human MMS22-Like, DNA Repair Protein (MMS22L) Interaktionspartner

  1. By specifically regulating RAD51 (zeige RAD51 ELISA Kits) activity at uncoupled replication forks, MMS22L-TONSL (zeige NFKBIL2 ELISA Kits) stabilizes perturbed replication forks by promoting replication fork reversal and stimulating their homologous recombination-mediated restart in vivo.

  2. new histones incorporated during DNA replication provide a signature of post-replicative chromatin, read by the human TONSL (zeige NFKBIL2 ELISA Kits)-MMS22L homologous recombination complex

  3. Our data strongly suggest that targeting MMS22L as well as its interaction with NFKBIL2 (zeige NFKBIL2 ELISA Kits) could be a promising strategy for novel cancer treatments.

  4. Results strongly suggest that the Mms22L-Nfkbil2 (zeige NFKBIL2 ELISA Kits) complex contributes to genome stability by regulating the chromatin state at stalled replication forks.

  5. These results indicate that MMS22L and TONSL (zeige NFKBIL2 ELISA Kits) are genome caretakers that stimulate the recombination-dependent repair of stalled or collapsed replication forks.

  6. MMS22L and TONSL (zeige NFKBIL2 ELISA Kits) are required for the maintenance of genome stability.

  7. This study identifies MMS22L-NFKBIL2 (zeige NFKBIL2 ELISA Kits) as components of the replication stress control pathway.

MMS22-Like, DNA Repair Protein (MMS22L) Antigen-Profil

Beschreibung des Gens

Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork- associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA (By similarity).

Genbezeichner und Symbole assoziert mit MMS22L

  • MMS22-like, DNA repair protein (Mms22l) Antikörper
  • MMS22 like, DNA repair protein (MMS22L) Antikörper
  • MMS22 like, DNA repair protein L homeolog (mms22l.L) Antikörper
  • MMS22 like, DNA repair protein (mms22l) Antikörper
  • MMS22-like, DNA repair protein (mms22l) Antikörper
  • C6orf167 Antikörper
  • dJ39B17.2 Antikörper
  • F730047E07Rik Antikörper
  • fc56d09 Antikörper
  • Gm134 Antikörper
  • RGD1304693 Antikörper
  • wu:fc56d09 Antikörper
  • zgc:194596 Antikörper

Bezeichner auf Proteinebene für MMS22L

protein MMS22-like , MMS22-like, DNA repair protein

GENE ID SPEZIES
313108 Rattus norvegicus
462893 Pan troglodytes
100026969 Monodelphis domestica
100137659 Xenopus laevis
100158637 Xenopus (Silurana) tropicalis
100602696 Nomascus leucogenys
253714 Homo sapiens
532916 Bos taurus
421799 Gallus gallus
212377 Mus musculus
563411 Danio rerio
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