anti-MAP/microtubule Affinity-Regulating Kinase 2 (MARK2) Antikörper

MARK2 encodes a member of the Par-1 family of serine/threonine protein kinases. Zusätzlich bieten wir Ihnen MAP/microtubule Affinity-Regulating Kinase 2 Proteine (10) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MARK2 2011 Q7KZI7
MARK2 13728 Q05512
MARK2 60328 O08679
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Top anti-MAP/microtubule Affinity-Regulating Kinase 2 Antikörper auf antikoerper-online.de

Showing 10 out of 111 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert ELISA, WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) . Dilution: 1:500~1000 MARK2 monoclonal antibody (M01), clone 3B12. Western Blot analysis of MARK2 expression in PC-12. Dilution: 1:500~1000 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$461.00
Details
Human Ziege Unkonjugiert ELISA, WB ABIN334431 (0.3µg/ml) staining of Human Brain (Cerebellum) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Kaninchen Unkonjugiert IC, IF, IHC, WB Immunofluorescent analysis of MARK2 staining in Jurkat cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of MARK2 staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Rind (Kuh) Kaninchen Unkonjugiert EIA, WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$533.50
Details
Human Kaninchen Unkonjugiert IF, ELISA, WB Western blot analysis of extracts from COS7 cells, using MARK2 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of A549 cells, using MARK2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IP, WB Western Blot: MARK2 Antibody [NBP1-71890] - Whole cell lysate from 293T (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and Jurkat (J; 50 mcg) cells. Affinity purified rabbit anti-MARK2 antibody used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 6 mcg/mg lysate. MARK2 was also immunoprecipitated by rabbit anti-MARK2 antibody NBP1-71889, which recognizes an upstream epitope. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using MARK2 (Ab-596) Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of HuvEc cells, using MARK2 (Ab-596) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-EMK Antibody (C-term)(ABIN392538) in mouse thymus tissue lysates (35 µg/lane). EMK(arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Kaninchen Unkonjugiert ELISA, IF, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, IHC (p), WB Anti-MARK2 antibody IHC staining of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1102962 concentration 10 ug/ml. 50 μL Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details

Am meisten referenzierte anti-MAP/microtubule Affinity-Regulating Kinase 2 Antikörper

  1. Human Monoclonal MARK2 Primary Antibody für ELISA, WB - ABIN560734 : Hezel, Gurumurthy, Granot, Swisa, Chu, Bailey, Dor, Bardeesy, Depinho: Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. in Molecular and cellular biology 2008 (PubMed)

  2. Human Polyclonal MARK2 Primary Antibody für IHC (p), WB - ABIN392538 : Blume-Jensen, Hunter: Oncogenic kinase signalling. in Nature 2001 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal MARK2 Primary Antibody für IP, WB - ABIN4332738 : Kruse, Krantz, Barker, Coletta, Rafikov, Luo, Højlund, Mandarino, Langlais: Characterization of the CLASP2 Protein Interaction Network Identifies SOGA1 as a Microtubule-Associated Protein. in Molecular & cellular proteomics : MCP 2017 (PubMed)

  4. Human Polyclonal MARK2 Primary Antibody für ELISA, WB - ABIN314316 : Depasquale, Thompson: Prognosis in human melanoma: PAR-1 expression is superior to other coagulation components and VEGF. in Histopathology 2008 (PubMed)

Weitere Antikörper gegen MAP/microtubule Affinity-Regulating Kinase 2 Interaktionspartner

Human MAP/microtubule Affinity-Regulating Kinase 2 (MARK2) Interaktionspartner

  1. In cell-based assays, Mark2 depletion indeed reduces Dvl (zeige DVL2 Antikörper) gene expression and interrupts neural stem cell (NSCs) growth and differentiation, which are likely to be mediated through a decrease in class IIa HDAC (zeige HDAC3 Antikörper) phosphorylation and reduced H3K4ac and H3K27ac occupancies at the Dvl1 (zeige DVL1 Antikörper)/2 promoters.

  2. HIV-1 did not stimulate widespread FEZ1 (zeige LZTS1 Antikörper) phosphorylation but, instead, bound microtubule (MT) affinity-regulating kinase 2 (MARK2) to stimulate FEZ1 (zeige LZTS1 Antikörper) phosphorylation on viral cores.

  3. Low expression of Mark2 is associated with uterine cervical neoplasms.

  4. In this study, through quantitative analysis of the complex formation between CagA (zeige S100A8 Antikörper) and PAR1b, the authors found that several CagA (zeige S100A8 Antikörper) species have acquired elevated PAR1b-binding activity via duplication of the CagA (zeige S100A8 Antikörper) multimerization motifs, while others have lost their PAR1b-binding activity.

  5. In the modeled structure of inactive MARK2, activation segment occludes the enzyme active site and assumes a relatively stable position.

  6. In conclusion, baicalin and DDP (zeige TIMM8A Antikörper) were synergistic at inhibiting proliferation and invasion of human lung cancer cells at appropriate dosages and incubation time in the presence or absence of DDP (zeige TIMM8A Antikörper) resistance. The attenuation of DDP (zeige TIMM8A Antikörper) resistance was associated with downregulation of MARK2 and p-Akt (zeige AKT1 Antikörper).

  7. MARK2 plays a role in promoting malignant phenotypes of lung cancer.

  8. Phosphorylation of RNF41 (zeige RNF41 Antikörper) by Par-1b regulates basolateral membrane targeting of laminin-111 receptors.

  9. induces asymmetric inheritance of plasma membrane domains via LGN (zeige GPSM2 Antikörper)-dependent mitotic spindle orientation in proliferating hepatocytes

  10. Perturbation of PAR1b and SHP2 (zeige PTPN11 Antikörper) by CagA (zeige S100A8 Antikörper) underlies the oncogenic potential of CagA (zeige S100A8 Antikörper).

Mouse (Murine) MAP/microtubule Affinity-Regulating Kinase 2 (MARK2) Interaktionspartner

  1. These results indicate that the basal localization of Par-1b in the outer epithelial cells is required for myoepithelial cell compression, and Par-1b is required for myoepithelial differentiation, regardless of its localization.

  2. data suggest ectopic PAR1 (zeige F2R Antikörper) expression is not tolerated in mouse platelets and indicate a different approach is required to develop a small animal model for the purpose of any future preclinical testing of PAR (zeige AFG3L2 Antikörper) antagonists as anti-platelet drugs

  3. a model whereby MARK2 negatively regulates insulin (zeige INS Antikörper) sensitivity in peripheral tissue through inhibition of KSR1 (zeige KSR1 Antikörper)

  4. ROCK1 (zeige ROCK1 Antikörper)/PAR-1b-dependent regulation of basement membrane placement is required for the coordination of tissue polarity and the elaboration of tissue structure in the developing submandibular salivary gland.

  5. PAR1b plays a novel role in the maintenance of mature dendritic spine morphology by regulating microtubule growth and the accumulation of p140Cap (zeige SRCIN1 Antikörper) in dendritic spines.

  6. Par-1b is a regulator of glucose metabolism and adiposity in the whole animal

  7. Interaction of MARK2 with CaMKI (zeige CAMK1 Antikörper) results in a novel, calcium-dependent pathway that plays an important role in neuronal differentiation.

  8. Akt (zeige AKT1 Antikörper) enhances the activity of PAR1 (zeige F2R Antikörper) to promote tau hyperphosphorylation at S262/S356, a tau species that is not recognized by the CHIP/Hsp90 (zeige HSP90 Antikörper) complex

  9. Coreduction of MARK2 and DCX (zeige DCX Antikörper) resulted in a partial restoration of the normal neuronal migration phenotype in vivo. The kinetic behavior of the centrosomes reflected the different molecular mechanisms activated when either protein was reduced.

MAP/microtubule Affinity-Regulating Kinase 2 (MARK2) Antigen-Profil

Protein Überblick

This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit MARK2

  • microtubule affinity regulating kinase 2 (MARK2) Antikörper
  • MAP/microtubule affinity regulating kinase 2 (Mark2) Antikörper
  • microtubule affinity regulating kinase 2 (Mark2) Antikörper
  • AU024026 Antikörper
  • Emk Antikörper
  • EMK-1 Antikörper
  • EMK1 Antikörper
  • mKIAA4207 Antikörper
  • Par-1 Antikörper
  • Par-1b Antikörper
  • Par1b Antikörper

Bezeichner auf Proteinebene für MARK2

ELKL motif kinase 1 , PAR1 homolog b , Ser/Thr protein kinase PAR-1B , serine/threonine protein kinase EMK , serine/threonine-protein kinase MARK2 , EMK-1 , EMK1 , serine/threonine kinase

GENE ID SPEZIES
100049882 Equus caballus
2011 Homo sapiens
13728 Mus musculus
483769 Canis lupus familiaris
535197 Bos taurus
60328 Rattus norvegicus
100737238 Sus scrofa
100731733 Cavia porcellus
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