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May involved in cell-cell interactions (By similarity).. Zusätzlich bieten wir Ihnen MDGA2 Antikörper (29) und MDGA2 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.
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A novel tumour suppressor gene, MDGA2, which is frequently inactivated by promoter methylation in Gastric cancer was identified. Promoter hypermethylation of MDGA2 represents a prognostic biomarker in patients with early stage Gastric cancer.
This finding provides further support for a link between variants in the MDGA2 gene and specific neuroticism-related phenotypes.
Polymorphisms of rs961616 in MAMDC1 gene were associated with rash and photosensitivity, but not disease risk, of systemic lupus erythematosus in Chinese population.
This study demonistrated suggested taht Rostral growth of commissural axons requires the cell adhesion molecule MDGA2
A novel uncharacterized gene, MAMDC1 (MAM domain containing glycosylphosphatidylinositol anchor 2, also known as MDGA2, MIM 611128), represents a putative susceptibility gene for systemic lupus erythematosus.
MAMDC1 gene is implicated in neuroticism.
No association of rs7151262 with neuroticism was found
results suggest that mutations in MDGA2 contribute to altered cortical processing through the dual disadvantages of elevated excitation and hyperconnectivity.
The neuronal migration deficit caused by loss of Laf4 can be partially rescued by Mdga2 over-expression, revealing an important functional relationship between these genes in a mouse model of intellectual disability.
MDGA binding and suppression of synaptogenic activity was selective for neuroligin-2 and not neuroligin-1 excitatory synapse organizer.
The transgene was inserted into the intronic sequences between exon 3 and exon 4 of the Mdga2 gene;the transgene was highly or under methylated in normal and deformed mice, respectively.
May involved in cell-cell interactions (By similarity).
MAM domain containing 1
, MAM domain-containing glycosylphosphatidylinositol anchor protein 2
, MAM domain-containing protein 1