Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
LIPA encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). Zusätzlich bieten wir Ihnen Lipase A Antikörper (91) und Lipase A Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.
Showing 3 out of 10 products:
Cholesterol esterase shows enantioselective inhibition for enantiomers of exo- and endo-2-norbornyl-N-n-butylcarbamates.
LAL activity is significantly reduced in NAFLD (zeige TSC2 ELISA Kits), compared to that in HCV patients. This finding is particularly evident in the pre-cirrhotic stage of disease. LAL activity is also correlated with platelet and white blood cell count, suggesting an analytic interference of portal-hypertension-induced pancytopenia on DBS (zeige MCF2L ELISA Kits)-determined LAL activity.
LAL plays a critical role in regulating mesenchymal stem cells' ability to stimulate tumor growth and metastasis, which provides a mechanistic basis for targeting LAL in MSCs to reduce the risk of cancer metastasis
Report a marked reduction of LAL activity in patients with cryptogenic cirrhosis.
LIPA mutations may have a role in with a clinical diagnosis of familial hypercholesterolemia
Use CRISPR/Cas9 techniques to knockout LIPA in human induced pluripotent stem cells and differentiate them to macrophages.
LIPA associated with Familial Hypercholesterolemia and Polygenic Hypercholesterolemia in patients with Acute Coronary Syndrome , age =65 years, and LDL-C levels >/=160 mg/dl.
Study demonstrates that liver cirrhosis from any etiology is characterized by a significant reduction of LAL activity but no known c.894G>A SNP, which is likely on an acquired base and independent from the etiology of hepatic disease.
Coronary artery disease-associated coding variant rs1051338 causes reduced lysosomal LAL protein and activity because of increased LAL degradation.
results indicate that LAL is the major acid RE hydrolase and required for functional retinoid homeostasis.
These findings suggest a strong association between impaired LAL activity and Non-alcoholic fatty liver disease.
Low LAL expression is associated with tumor growth and metastasis.
The activity of lysosomal acid lipase was also decreased on treatment of macrophages with each modified LDL.
hLAL (zeige LIPF ELISA Kits) expression reduced tumor-promoting myeloid-derived suppressive cells in the liver of lal(-/-) mice
Results indicate that LAL has a critical role in regulating MDSCs' ability to directly stimulate cancer cell proliferation and overcome immune rejection of cancer metastasis in allogeneic mice through modulation of the mTOR (zeige FRAP1 ELISA Kits) pathway.
effect the loss of SOAT2 function has on tissue esterified cholesterol sequestration in lysosomal acid lipase-deficient mice in a model of cholesteryl ester storage disease
Lipolysis of triacylglycerol substrates by LAL is important for M2 macrophage activation, and its inhibition suppresses M2 activation.
LAL regulates endothelial cell function through interaction with myeloid-derived suppressor cells and modulation of the mTOR (zeige FRAP1 ELISA Kits) pathway, which provide mechanistic basis for targeting MDSCs or mTOR (zeige FRAP1 ELISA Kits) to rejuvenate EC functions in LAL deficiency-related diseases
These results indicate a crucial role of LAL-regulated mTOR signaling in the production and function of CD11b(+)Ly6G(+) cells.
SR-BI (zeige SCARB1 ELISA Kits)-delivered HDL (zeige HSD11B1 ELISA Kits)-CEs are hydrolyzed by hepatic CEH (zeige EPHX2 ELISA Kits) and utilized for bile acid synthesi
This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
lipase A, lysosomal acid, cholesterol esterase (Wolman disease)
, lysosomal acid lipase/cholesteryl ester hydrolase
, lipase A, lysosomal acid, cholesterol esterase
, lysosomal acid lipase/cholesteryl ester hydrolase-like
, acid cholesteryl ester hydrolase
, cholesterol ester hydrolase
, cholesteryl esterase
, lysosomal acid lipase
, sterol esterase
, Cholesterol esterase (pancreatic) see D3Wox12 D3Wox13 D3Wox26 and D3Mgh25
, lysosomal acid lipase 1
, lysosomal acid lipase A
, pancreatic cholesterol esterase
, lipase A