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The protein encoded by LILRA5 is a member of the leukocyte immunoglobulin-like receptor (LIR) family. Zusätzlich bieten wir Ihnen LILRA5 Antikörper (60) und LILRA5 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.
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LILRA5/LIR9/ILT11 does not play a role in any MHCI recognition but could possibly bind to non-MHCI ligand(s) on the target cells to provide a novel immune regulation mechanism
LILRC1 and LILRC2 both have two extracellular Ig-like domains and a cytoplasmic tail devoid of any known signaling motifs. The transmembrane regions contain an arginine residue.
The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described.
CD85 antigen-like family member F
, immunoglobulin-like transcript 11 protein
, leukocyte Ig-like receptor 9
, leukocyte immunoglobulin-like receptor 9
, leukocyte immunoglobulin-like receptor subfamily A member 5
, leukocyte immunoglobulin-like receptor subfamily A member 5 soluble
, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 7
, leukocyte immunoglobulin-like receptor