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LILRA4 encodes an immunoglobulin-like cell surface protein preferentially expressed in plasmacytoid dendritic cells (PDCs). Zusätzlich bieten wir Ihnen Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 4 Antikörper (79) und viele weitere Produktgruppen zu diesem Protein an.
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Crosslinked ILT7 favours the differentiation of immature plasmacytoid dendritic cells into antigen-presenting cells rather than IPC.
ILT7 may exert its immunomodulatory activity only on immature circulating plasmacytoid dendritic cells (pDCs), providing a basic homeostatic mechanism rather than negative feedback control on activated pDCs.
Intracellular expression of the TCL1 as well as membrane and intracellular expression of ILT7 in plasmacytoid dendritic cell leukemia (pDCL) samples and 61 non-pDC acute leukemia samples, were tested.
the expression of immunoglobulin-like transcript 7, in plasmacytoid dendritic cells
ILT7 protein associates with the signal adapter protein Fc epsilonRI gamma to form a receptor complex in dendritic cells.
key regulator of human pDC function and interferon type I production.
Data show that BST2 directly binds to purified ILT7, initiates signaling via the ILT7-FcepsilonRIgamma complex, and regulates TLR7/9 responses in plasmacytoid dendritic cells.
This gene encodes an immunoglobulin-like cell surface protein preferentially expressed in plasmacytoid dendritic cells (PDCs). This gene is highly expressed in PDCs, and is found to be rapidly down-regulated by interleukin 3 (IL3). This gene is one of the 19 highly related genes that form a leukocyte receptor gene cluster (LRC) at chromosomal region 19q13.4.
leukocyte immunoglobulin-like receptor subfamily A member 4
, immunoglobulin-like transcript 7
, CD85 antigen-like family member G
, leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 4