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Involved in bone homeostasis.
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low circulating plasma level of LRRc17 might serve as an independent and additive risk factor for osteoporotic fractures.
Whole-genome microarray mRNA-expression profiles of myofibroblasts and skin fibroblasts revealed four additional genes that are significantly differentially expressed in these two cell types: NKX2-3 and LRRC17 in myofibroblasts and SHOX2 and TBX5 in skin fibroblasts
These results demonstrated a novel inhibitory activity of LRRc17 in RANKL (zeige TNFSF11 ELISA Kits)-induced osteoclastogenesis.
Involved in bone homeostasis. Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors (By similarity).
leucine-rich repeat-containing protein 17
, 37 kDa leucine-rich repeat (LRR) protein
, leucine-rich repeat (LRR) protein