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LEFTY-A encodes a member of the TGF-beta family of proteins. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.
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LeftyA leads to disruption of Rac1 and Pak1 activity with subsequent actin depolymerization, cell softening and cell shrinkage.
LEFTY2 (zeige LEFTY2 Antikörper) down-regulates MKi67 (zeige MKI67 Antikörper) expression and FAK (zeige PTK2 Antikörper) activity, up-regulates miR (zeige MLXIP Antikörper)-200a and E-cadherin (zeige CDH1 Antikörper), and is thus a powerful negative regulator of endometrial cell proliferation and migration.
LEFTY2 (zeige LEFTY2 Antikörper) regulates the expression and activity of ENaC (zeige SCNN1A Antikörper) in endometrial epithelial cells via SGK1 (zeige SGK1 Antikörper).
Lefty (zeige LEFTY2 Antikörper) A may account for the tumor suppressive activity of human adult stem cells.
Findings suggest that Lefty2 (zeige LEFTY2 Antikörper) is negatively modulated by miR (zeige MLXIP Antikörper)-302s in hESCs, which plays an important role in maintaining the balance between pluripotency and germ layer specification.
findings show that the TGFB4 (ebaf (zeige LEFTY2 Antikörper)) mRNA has distinct tumor specific expression
nodal and the inhibitors of Nodal signaling, lefty (zeige LEFTY2 Antikörper)-A and lefty (zeige LEFTY2 Antikörper)-B, are down-regulated very early upon differentiation of human embryonic stem cells
Addition of recombinant LEFTY (zeige LEFTY2 Antikörper)-A to explants induced MMP-9 (zeige MMP9 Antikörper) in most samples, a response prevented by ovarian steroids.
LEFTY (zeige LEFTY2 Antikörper) proteins, which are known to play a major role during mouse gastrulation, are transiently expressed during human embryonic stem cell differentiation.
This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. Alternate splicing of this gene results in multiple transcript variants.
, endometrial bleeding-associated factor
, left-right determination factor A
, protein lefty-2
, protein lefty-A
, transforming growth factor beta-4