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LGALS9 was initially thought to represent a pseudogene of galectin 9; however, this transcript has good exon-intron structure and encodes a predicted protein of the same size as and highly similar to galectin 9. Zusätzlich bieten wir Ihnen Lectin, Galactoside-Binding, Soluble, 9 Kits (61) und Lectin, Galactoside-Binding, Soluble, 9 Proteine (35) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 195 products:
Mouse (Murine) Polyclonal LGALS9 Primary Antibody für CyTOF, FACS - ABIN4899254
Iqbal, Sampaio, Maione, Greco, Niki, Hirashima, Perretti, Cooper: Endogenous galectin-1 and acute inflammation: emerging notion of a galectin-9 pro-resolving effect. in The American journal of pathology 2011
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Human Polyclonal LGALS9 Primary Antibody für ELISA, WB - ABIN561667
Bellac, Coimbra, Simon, Imboden, Leib: Gene and protein expression of galectin-3 and galectin-9 in experimental pneumococcal meningitis. in Neurobiology of disease 2007
Show all 2 Pubmed References
Human Polyclonal LGALS9 Primary Antibody für IF (p), IHC (p) - ABIN733163
Daley, Mani, Mohan, Akkad, Ochi, Heindel, Lee, Zambirinis, Pandian, Savadkar, Torres-Hernandez, Nayak, Wang, Hundeyin, Diskin, Aykut, Werba, Barilla, Rodriguez, Chang, Gardner, Mahal, Ueberheide et al.: Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance. ... in Nature medicine 2017
in a model of experimental autoimmune encephalomyelitis, we show that an agonist of DR3 (zeige TNFRSF25 Antikörper) suppressed disease, correlating with expansion of CD4 (zeige CD4 Antikörper)+Foxp3 (zeige FOXP3 Antikörper)+ Tregs, and this protective effect was lost in Galectin-9-/- mice
Galectin 9 is a novel dectin 1 (zeige CLEC7A Antikörper) ligand in pancreatic ductal adenocarcinoma. Upon disruption of the dectin 1 (zeige CLEC7A Antikörper)-galectin 9 axis, CD4 (zeige CD4 Antikörper)(+) and CD8 (zeige CD8A Antikörper)(+) T cells, which are dispensable for PDA progression in hosts with an intact signaling axis, become reprogrammed into indispensable mediators of anti-tumor immunity.
The Gal-9/Tim-3 (zeige HAVCR2 Antikörper) signal is important for the regulation of decidua NK cells function, which is beneficial for the maintenance of a normal pregnancy.
These results indicate the possibility that cooperative binding of oligosaccharide and neighboring polypeptide structures of monoclonal IgE to galectin-9 affects the overall affinity and specificity of the IgE-lectin interaction.
galectin-9 functions as a novel alarmin by augmenting the inflammatory response in sepsis development during pulmonary F. novicida infection.
Gal-9 has a role in the maintenance of hepatic homeostasis and preventing liver ischemia-reperfusion injury
Gal-9, a natural TIM-3 (zeige HAVCR2 Antikörper) ligand, was produced primarily by and released from ischemia-reperfusion-stressed hepatocytes, both in vivo and in vitro.
Galectin-9 functions as an astrocyte-microglia communication signal and promotes cytokine production from microglia in a Tim-3 (zeige HAVCR2 Antikörper) independent manner.
galectin-9, in addition to being an effector molecule for regulatory T cells cells, acts synergistically with TGF-beta (zeige TGFB1 Antikörper) to enforce iTreg cell differentiation and maintenance.
Galectin-9 is a suppressor of T and B cells and predicts the immune modulatory potential of mesenchymal stromal cell preparations.
Results show that human acute myeloid leukemia (zeige BCL11A Antikörper) (AML (zeige RUNX1 Antikörper)) cells possess a secretory pathway which leads to the production and release of soluble Tim-3 (zeige HAVCR2 Antikörper) and galectin-9. Both proteins prevent the activation of NK cells and impair their AML (zeige RUNX1 Antikörper) cell-killing activity.
Significantly elevated Gal-9 levels were found in both minimal-mild (I-II) and moderate-severe (III-IV) stages of endometriosis in comparison with healthy controls.
We investigated tumor-infiltrating CD4 (zeige CD4 Antikörper) and CD8 (zeige CD8A Antikörper) T cells and the expression of PD-L1 (zeige CD274 Antikörper), Galectin-9, and XAGE1 (zeige XAGE1A Antikörper) in stage I to IIIA lung adenocarcinomas using a tissue microarray to deduce their contribution to overall survival, and our data showed that PD-L1 (zeige CD274 Antikörper) expression was a positive indicator, whereas Galectin-9 and XAGE1 (zeige XAGE1A Antikörper) expression was negative.
Tim3 (zeige HAVCR2 Antikörper)/Gal-9 alleviates the inflammation of TAO patients via suppressing Akt (zeige AKT1 Antikörper)/NF-kappaB (zeige NFKB1 Antikörper) signaling pathway.
Low Gal-9 expression is associated with pancreatic and ampullary cancer.
X-ray structure of a protease-resistant mutant form of human galectin-9 having two carbohydrate recognition domains with a metal-binding site has been presented.
These findings may indicate that an increase in the Gal-9 level, a novel immune checkpoint molecule, can reflect immune-related adverse effects of various biotherapies.
Our data suggest a role of galectin-9 in regulating HIV transcription and viral production in vivo during therapy
these data suggest that the high Tim-3 (zeige HAVCR2 Antikörper) expression in monocytes could be utilized by tumor-promoting Gal-9 expression on CD4 (zeige CD4 Antikörper)(+) T cells
The Tim-3 (zeige HAVCR2 Antikörper)/Gal-9 pathway might link disease progression with T cell exhaustion during bovine leukemia virus infection.
The relative abundance of PIBF (zeige PIBF1 Antikörper), LGALS1 (zeige LGALS1 Antikörper), LGALS3 (zeige LGALS2 Antikörper), LGALS3BP (zeige LGALS3BP Antikörper), and LGALS9 mRNA would display a differential expression pattern in the endometrium.
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene.
lectin, galactoside-binding, soluble, 9
, galactoside-binding soluble lectin 9
, galectin 9
, lectin, galactoside-binding, soluble, 9 (galectin 9)
, lectin, galactose binding, soluble 5
, tumor antigen HOM-HD-21
, urate transporter/channel protein
, 36 kDa beta-galactoside-binding lectin
, Lectin galactose binding soluble 9 (Galectin-9)
, Lectin, galactose binding, soluble 9 (Galectin-9)
, urate transporter/channel
, urate transporter
, urate transporter/channel protein, isoform (UATp,i)