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The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions.
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Diabetic mice model shows that increased O-linked N-Acetyl-glucosamine (O-GlcNAc) is responsible for reduced Gal-7 expression in keratinocytes exposed to high glucose environment.
The data suggest that gal-7 could potentiate the phenotype of HER-2 (zeige ERBB2 ELISA Kits) positive primary breast cancer.
results indicate that an excess of galectin-7 (zeige LGALS7 ELISA Kits) leads to a destabilisation of adherens junctions associated with defects in epidermal repair
Overexpression of galectin-7 (zeige LGALS7 ELISA Kits) increased the resistance of melanoma cells to apoptosis while inducing de novo egr-1 (zeige EGR1 ELISA Kits) expression.
In cardiac transplantation galectin-7 (zeige LGALS7 ELISA Kits) relates to acute allograft rejection and T-cell responses possibly as an accelerant.
Extracellular superoxide dismutase (zeige SOD3 ELISA Kits) plays a role not only as a reactive oxygen species scavenger, but also as a pro-apoptotic factor via COX-2 (zeige COX2 ELISA Kits)/galectin-7 (zeige LGALS7 ELISA Kits) pathways in the epidermis.
Galectin-7 (zeige LGALS7 ELISA Kits) modulates the length of the primary cilia and wound repair in polarized kidney epithelial cells.
Data show that high levels of galectin-7 (zeige LGALS7 ELISA Kits) expression in breast cancer cells drastically increased their ability to metastasize to lungs and bones, and were restricted to high-grade breast carcinomas.
Galectin-3 (zeige LGALS3 ELISA Kits) and galectin-7 (zeige LGALS7 ELISA Kits) play a role in corneal epithelial wound healing.
Upregulation of galectin-7 (zeige LGALS7 ELISA Kits) in murine lymphoma cells is associated with progression toward an aggressive phenotype.
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:3963) is found adjacent to, but on the opposite strand on chromosome 19.
, lectin, galactose binding, soluble 7
, galectin 7B
, keratinocyte lectin 14
, lectin galactoside-binding soluble 7
, p53-induced gene 1 protein
, p53-induced protein 1