Kruppel-Like Factor 17 Proteine (KLF17)

Transcription repressor that binds to the promoter of target genes and prevents their expression. Zusätzlich bieten wir Ihnen KLF17 Antikörper (63) und KLF17 Kits (12) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
KLF17 128209 Q5JT82
KLF17 75753 Q8CFA7
Ratte KLF17 KLF17 298449  
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Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Hefe Wildschwein His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,067.17
Details

KLF17 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human

Mouse (Murine)

Weitere Proteine zu Kruppel-Like Factor 17 (KLF17) Interaktionspartnern

Xenopus laevis Kruppel-Like Factor 17 (KLF17) Interaktionspartner

  1. Data suggest that Neptune is a new member of hatching gland specifier and plays a physiological role in determination and specification of multiple lineages derived from the NPB region.

Human Kruppel-Like Factor 17 (KLF17) Interaktionspartner

  1. Low Expressions of KLF17 is associated with lung adenocarcinoma.

  2. Suggest that KLF17 inhibits esophageal carcinoma development and may serve as a potential therapeutic target.

  3. Enhanced KLF17 expression sensitizes ERalpha (zeige ESR1 Proteine)-positive breast cancer cells to endocrine therapy.KLF17-ERalpha (zeige ESR1 Proteine) interaction plays a potential role in inhibition of ERalpha (zeige ESR1 Proteine)-dependent breast cancer progression.

  4. KLF17 empowers TGF-beta (zeige TGFB1 Proteine)/Smad (zeige SMAD1 Proteine) signaling by targeting Smad3 (zeige SMAD3 Proteine)-dependent pathway to suppress tumor growth and metastasis during cancer progression.

  5. Tumor-suppressive p53 (zeige TP53 Proteine) signaling is critical for KLF17 to inhibit cancer metastasis in Non-small Cell Lung Cancer.

  6. A small subset of Myoepithelial tumors harbor FUS (zeige FUS Proteine) rearrangements, two thirds of them being associated with KLF17 fusion.

  7. In this review, we focus on the functions, roles, and regulatory networks of these five KLFs in HCC (zeige FAM126A Proteine), summarize key pathways, and propose areas for further investigation

  8. The reduced expression of KLF17 promoted the motility and proliferation ability of TPC1 (zeige TPCN1 Proteine) cells by altering the expression of tight junction protein 1 (zeige TJP1 Proteine) and Snai1 (zeige SNAI1 Proteine), and activating the AKT (zeige AKT1 Proteine) pathway by upregulating inhibitor of DNA binding 1 (zeige ID1 Proteine).

  9. mutant p53 (zeige TP53 Proteine) enhances cancer progression by inhibiting KLF17 expression in invasive breast carcinoma cells

  10. The reduced expression of KLF17 protein in gastric cancer was correlated with tumor size, pN stage and lymphovascular invasion and was an independent predictor for poor survival in patients undergoing surgery for gastric cancer.

Mouse (Murine) Kruppel-Like Factor 17 (KLF17) Interaktionspartner

  1. ZFP393 functions as a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development

  2. demonstrate that KLF17 expression is significantly downregulated in primary human breast cancer samples and that the combined expression pattern of KLF17 and Id1 (zeige ID1 Proteine) can serve as a potential biomarker for lymph node metastasis in breast cancer

KLF17 Protein Überblick

Protein Überblick

Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development (By similarity).

Genbezeichner und Symbole assoziert mit Kruppel-Like Factor 17 Proteine (KLF17)

  • Kruppel-like factor 17 L homeolog (klf17.L)
  • Kruppel like factor 17 (KLF17)
  • Kruppel-like factor 17 (klf17)
  • Kruppel-like factor 17 (Klf17)
  • Kruppel like factor 17 (Klf17)
  • 7420700M05Rik Protein
  • AA420409 Protein
  • AU043468 Protein
  • C85123 Protein
  • D4Ertd561e Protein
  • Gzf Protein
  • neptune Protein
  • rp4-675g8.1 Protein
  • Zfp393 Protein
  • ZNF393 Protein

Bezeichner auf Proteinebene für Kruppel-Like Factor 17 Proteine (KLF17)

Kruppel-like factor 17 , Kruppel-like transcription factor neptune , novel kruppel-like factor family protein , krueppel-like factor 17-like , Krueppel-like factor 17 , novel zinc-finger protein , zinc finger protein 393 , germ cell specific zinc finger protein , germ cell-specific zinc finger protein

GENE ID SPEZIES
398243 Xenopus laevis
702810 Macaca mulatta
734094 Xenopus (Silurana) tropicalis
100436573 Pongo abelii
100599780 Nomascus leucogenys
128209 Homo sapiens
75753 Mus musculus
298449 Rattus norvegicus
100302639 Sus scrofa
516413 Bos taurus
100725519 Cavia porcellus
101108444 Ovis aries
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