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KLC3 encodes a member of the kinesin light chain gene family. Zusätzlich bieten wir Ihnen KLC3 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
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Microtubule-bound kinesin-1 and kinesin-3 motor domains were visualized at multiple steps in their ATPase (zeige DNAH8 Antikörper) cycles--including their nucleotide-free states--at approximately 7 A resolution using cryo-electron microscopy.
Rat KLC3 interacts with KHC (zeige KIF5B Antikörper) and microtubules in vitro. Expressed in spleen, intestine, brain, ovary, testis. Testis expression restricted to post-meiotic spermatids.
Rat KLC3 associates with the outer dense fibers (zeige ODF1 Antikörper) of maturing sperm tails.
KLC3 plays a role during spermiogenesis in the development of the midpiece and in the normal function of spermatozoa
This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria.
kinesin light chain 3
, kinesin light chain 2
, kinesin light chain KLCt