anti-Kinase Suppressor of Ras 1 (KSR1) Antikörper

Location-regulated scaffolding protein connecting MEK to RAF.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Maus KSR1 KSR1 16706 Q61097
Anti-Ratte KSR1 KSR1 360573  
Anti-Human KSR1 KSR1 8844 Q8IVT5
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Top anti-Kinase Suppressor of Ras 1 Antikörper auf antikoerper-online.de

Showing 10 out of 109 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IC, IF, IHC, WB   200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, treated with PDGF 50ng/ml 20', using KSR (Ab-392) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using KSR (Ab-392) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from HepG2 cells, using KSR (Phospho-Ser392) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain, using KSR (Phospho-Ser392) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Maus Kaninchen Unkonjugiert WB Mouse Ksr1 Antibody (C-term) (ABIN658071) western blot analysis in mouse NIH-3T3 cell line lysates (35 µg/lane). This demonstrates the Ksr1 antibody detected the Ksr1 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, IHC (p), WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-KSR1 Pab (ABIN392257) in A375 cell lysate. KSR1 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of anti-KSR1 Pab in T47D cell line lysate. KSR1(arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of anti-KSR1 Pab in T47D cell line lysate. KSR1(arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti KSR1 Polyclonal Antibody, Unconjugated (ABIN700645) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$306.90
Details

Weitere Antikörper gegen Kinase Suppressor of Ras 1 Interaktionspartner

Fruit Fly (Drosophila melanogaster) Kinase Suppressor of Ras 1 (KSR1) Interaktionspartner

  1. the atypical C1 domain, the CC-SAM (zeige TTN Antikörper) domain is required to target KSR-1 to the plasma membrane.

  2. KSR is a scaffold required for activation of the ERK/MAPK (zeige MAPK1 Antikörper) module.

  3. Review discusses the possibility that KSR, a RAF (zeige ARAF Antikörper)-like protein, does not solely act as a scaffold, but directly induces RAF (zeige RAF1 Antikörper) catalytic function by a kinase-independent mechanism apparently shared by RAF (zeige RAF1 Antikörper)-like proteins.

Mouse (Murine) Kinase Suppressor of Ras 1 (KSR1) Interaktionspartner

  1. DiRas3 (zeige DIRAS3 Antikörper) binds to KSR1 independently of its interaction with activated Ras and RAF (zeige RAF1 Antikörper).

  2. praja2 (zeige PJA2 Antikörper) regulates KSR1 stability and mitogenic signaling.

  3. These results suggest that Rap1 (zeige TERF2IP Antikörper) activation of ERKs requires PKA phosphorylation and KSR binding.

  4. Data show that caveolin-1 is necessary for optimal KSR1-dependent ERK activation by growth factors and oncogenic Ras.

  5. propose that phosphorylation of Tyr (zeige TYR Antikörper)(728) may regulate the transition between the scaffolding and the catalytic function of KSR1 serving as a control point used to fine-tune cellular responses

  6. Data indicate that phosphorylation of BRAF (zeige BRAF Antikörper) by AMPK (zeige PRKAA1 Antikörper) disrupts its association with KSR1.

  7. Despite its role in mTORC1 activation, KSR1 is not required in vivo for mTOR (zeige FRAP1 Antikörper)-dependent T cell differentiation.

  8. Ksr1 plays a dispensable role in lipopolysaccharide (LPS (zeige TLR4 Antikörper))-induced ERK (zeige EPHB2 Antikörper) activation in alveolar macrophages and does not contribute to the development of acute lung injury in the LPS (zeige TLR4 Antikörper) model.

  9. the atypical C1 domain, the CC-SAM (zeige TTN Antikörper) domain is required to target KSR-1 to the plasma membrane.

  10. The loss of Ksr1 inhibits Ras/Mapk (zeige MAPK1 Antikörper) pathway signaling leading to increased Myc (zeige MYC Antikörper)-induced B-cell apoptosis, and this results in reduced B-cell transformation and lymphoma development.

Human Kinase Suppressor of Ras 1 (KSR1) Interaktionspartner

  1. praja2 (zeige PJA2 Antikörper) regulates KSR1 stability and mitogenic signaling.

  2. Data show that neurofibromin 2 (Merlin (zeige NF2 Antikörper)) suppresses proliferation and adhesion, at least partly, through inhibiting kinase suppressor of Ras 1 (KSR1) and DCAF1 (zeige VPRBP Antikörper) protein.

  3. These results suggest that Rap1 (zeige RABGEF1 Antikörper) activation of ERKs requires PKA phosphorylation and KSR binding.

  4. Upregulation of KSR1 is associated with Colorectal cancer.

  5. the relative mRNA copy values of KSR1, ERK1 and ERK2 in the cancer tissues were 2.43 +/- 0.49, 2.10 +/- 0.44 and 3.65 +/- 0.94..EGb 761 enhanced the chemotherapy sensitivity through suppression of the KSR1-mediated ERK1/2 pathway in gastric cancer

  6. KSR1 rs2241906 variants may predict survival in patients with advanced ERalpha (zeige ESR1 Antikörper)+ BC treated with adjuvant TAM (zeige CCNA1 Antikörper).

  7. KSR1 is coordinately regulated with Notch (zeige NOTCH1 Antikörper) signaling and oxidative phosphorylation in papillary thyroid cancer.

  8. KSR1 stabilizes BRCA1 by reducing BRCA1 ubiquitination, inhibits tumor growth through BRCA1, and regulates BRCA1 stability via elevated BARD1 (zeige BARD1 Antikörper) abundance and increased BRCA1-BARD1 (zeige BARD1 Antikörper) interaction

  9. Data show that caveolin-1 is necessary for optimal KSR1-dependent ERK activation by growth factors and oncogenic Ras.

  10. Data indicate that phosphorylation of BRAF (zeige BRAF Antikörper) by AMPK (zeige PRKAA1 Antikörper) disrupts its association with KSR1.

Kinase Suppressor of Ras 1 (KSR1) Antigen-Profil

Protein Überblick

Location-regulated scaffolding protein connecting MEK to RAF. Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex. By itself, it has no demonstrated kinase activity.

Genbezeichner und Symbole assoziert mit KSR1

  • kinase suppressor of ras 1 (KSR1) Antikörper
  • kinase suppressor of ras (ksr) Antikörper
  • kinase suppressor of ras 1 (Ksr1) Antikörper
  • AW492498 Antikörper
  • B-KSR1 Antikörper
  • CG2899 Antikörper
  • D11Bhm183e Antikörper
  • D11Bhm184e Antikörper
  • dKsr Antikörper
  • Dmel\\CG2899 Antikörper
  • EK3-1 Antikörper
  • hb Antikörper
  • Ksr Antikörper
  • Ksr-1 Antikörper
  • l(3)j5E2 Antikörper
  • RSU2 Antikörper
  • SR3-1 Antikörper

Bezeichner auf Proteinebene für KSR1

CG2899-PA , kinase suppressor of Ras85D , ksr-PA , suppressor of Ras1 3-1 , kinase suppressor of Ras 1 , mKSR1 , protein Hb

GENE ID SPEZIES
100071912 Equus caballus
40660 Drosophila melanogaster
16706 Mus musculus
360573 Rattus norvegicus
8844 Homo sapiens
427839 Gallus gallus
610451 Canis lupus familiaris
100511282 Sus scrofa
100138565 Bos taurus
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