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anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) Antikörper

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. Zusätzlich bieten wir Ihnen Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 Proteine (9) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
KIR2DL1 3802 P43626
KIR2DL1    
KIR2DL1    
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Top anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 Antikörper auf antikoerper-online.de

Showing 10 out of 84 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IP, WB Amount and Sample Type: Lane 1:2x107 KIR2DL1 transfected NKL cells IP Antibody: KIR2DL1 Amount of IP Antibody: Primary Antibody: KIR2DL1 Primary Antibody Dilution: 1: x50Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:x0,000 Gene Name: KIR2DL1 Submitted by: Kerry S. Campbell, Institute for Cancer Research. 100 μL 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB Western blot analysis of extracts of HepG2, using KIR2DL1antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6276823 at 1/100 staining Human liver cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11 bis 12 Tage
$390.77
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of Raji and mouse liver cells, using KIR2DL1 antibody. 100 μL 11 bis 13 Tage
$366.77
Details
Human Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$551.83
Details
Human Maus Unkonjugiert IP, ELISA, WB 100 μL 11 bis 14 Tage
$522.50
Details
Human Maus Unkonjugiert EIA, IP, WB Western blot analysis Recombinant human protein KIR2DL1, KIR2DL3, KIR2DS4 and KIR2DL4 (each 50ng per well) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human KIR2DL1 (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. 0.1 mL 6 bis 8 Tage
$390.50
Details
Human Kaninchen FITC FACS 100 Tests 14 bis 16 Tage
$236.18
Details
Human Kaninchen PE FACS 100 Tests 14 bis 16 Tage
$300.88
Details
Human Kaninchen Unkonjugiert ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg 13 bis 16 Tage
$332.00
Details
Human Kaninchen APC FACS 100 Tests 14 bis 16 Tage
$365.59
Details

Am meisten referenzierte anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 Antikörper

  1. Human Monoclonal KIR2DL1 Primary Antibody für FACS - ABIN4898668 : Achour, Baychelier, Besson, Arnoux, Marty, Hannoun, Samuel, Debré, Vieillard: Expansion of CMV-mediated NKG2C+ NK cells associates with the development of specific de novo malignancies in liver-transplanted patients. in Journal of immunology (Baltimore, Md. : 1950) 2013 (PubMed)
    Show all 9 Pubmed References

  2. Human Monoclonal KIR2DL1 Primary Antibody für FACS - ABIN4898664 : Alici, Sutlu, Björkstrand, Gilljam, Stellan, Nahi, Quezada, Gahrton, Ljunggren, Dilber: Autologous antitumor activity by NK cells expanded from myeloma patients using GMP-compliant components. in Blood 2008 (PubMed)
    Show all 6 Pubmed References

  3. Human Monoclonal KIR2DL1 Primary Antibody für CyTOF, FACS - ABIN4900802 : Horowitz, Guethlein, Nemat-Gorgani, Norman, Cooley, Miller, Parham: Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)
    Show all 5 Pubmed References

  4. Human Monoclonal KIR2DL1 Primary Antibody für FACS - ABIN4898674 : Ballan, Vu, Long, Loo, Michaëlsson, Barbour, Lanier, Wiznia, Abadi, Fennelly, Rosenberg, Nixon et al.: Natural killer cells in perinatally HIV-1-infected children exhibit less degranulation compared to HIV-1-exposed uninfected children and their expression of KIR2DL3, NKG2C, and NKp46 correlates with ... in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)
    Show all 5 Pubmed References

  5. Human Monoclonal KIR2DL1 Primary Antibody für FACS - ABIN4898662 : Kawashima, Maeda, Adachi, Takeuchi, Yamamoto, Izumiya, Hayashi, Furihata, Udaka, Fukaya: Human leukocyte antigen-G, a ligand for the natural killer receptor KIR2DL4, is expressed by eutopic endometrium only in the menstrual phase. in Fertility and sterility 2009 (PubMed)
    Show all 4 Pubmed References

  6. Human Monoclonal KIR2DL1 Primary Antibody für IP, ELISA - ABIN532938 : Fan, Long, Wiley: Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1-HLA-Cw4 complex. in Nature immunology 2001 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal KIR2DL1 Primary Antibody für FACS - ABIN4898661 : Lehmann, Spanholtz, Sturtzel, Tordoir, Schlechta, Groenewegen, Hofer: IL-12 directs further maturation of ex vivo differentiated NK cells with improved therapeutic potential. in PLoS ONE 2014 (PubMed)
    Show all 2 Pubmed References

  8. Human Monoclonal KIR2DL1 Primary Antibody für CyTOF, FACS - ABIN4900801 : Høglund, Holmøy, Harbo, Maghazachi: A one year follow-up study of natural killer and dendritic cells activities in multiple sclerosis patients receiving glatiramer acetate (GA). in PLoS ONE 2013 (PubMed)

  9. Human Monoclonal KIR2DL1 Primary Antibody für FACS - ABIN4898672 : Charoudeh, Terszowski, Czaja, Gonzalez, Schmitter, Stern: Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection. in European journal of immunology 2013 (PubMed)

Weitere Antikörper gegen Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 Interaktionspartner

Human Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) Interaktionspartner

  1. More NK cells educated through KIR2DL1 and KIR3DL1, but not KIR2DL3, responded to antibody-dependent (AD) NK cell activation than their uneducated counterparts.

  2. matching of KIR2DL1, 2DS1, and 2DS2 in donors with their HLA-C ligands in recipients is associated with increased GvHD, and holds potential for selection of HSCT donors.

  3. In a case-control study of pre-eclampsia, the authors show that KIR2DL1A, not KIR2DL1B, associates with increased Pre-Eclampsia disease risk.

  4. Distinguishing these haplotypes are independent mutations in KIR2DL1.

  5. KIR 2D (L1, L3, L4, S4) and KIR 3DL1 expression was correlated with poor prognosis in non-small cell lung carcinoma patients.

  6. A negative association between the KIR2DL1 polymorphism and susceptibility to type 1 diabetes mellitus was found.

  7. the surface organization of paired killer Ig-like receptors (KIR), KIR2DL1 and KIR2DS1, on human primary natural killer cells and cell lines, was examined.

  8. A significantly higher risk of chronic rejection after kidney transplantation was observed when recipient (r) and donor (d) pairs completely lacked the two functional rKIR-dHLA ligand combinations rKIR2DL1/dHLA-C2 and rKIR3DL1/dHLA-Bw4.

  9. CD16+ cells were significantly more frequent among Natural Killer (NK) cells negative for the inhibitory KIR (iKIR) KIR2DL1, KIR2DL3, and KIR3DL1 than those positive for any one of these iKIR to the exclusion of the others, making iKIR+ NK cells poorer antibody dependent cellular cytotoxicity effectors than iKIR- NK cells.

  10. Data indicate that a novel variant allele, KIR2DL1*031, was identified by cDNA cloning and haplotype sequencing of killer cell immunoglobulin-like receptor 2DL1 (KIR2DL1) gene.

  11. KIR2DL1-C2C2 is less frequent in type 1 diabetes in Saudi children

  12. Influence of Differently Licensed KIR2DL1-Positive Natural Killer Cells in Transplant Recipients with Acute Leukemia

  13. Educated natural killer cells expressing KIR2DL1 display functional advantage for anti-HIV-1 antibody-dependent activation.

  14. KIR2DL1*022 and 2DL1*026 evolved in the KhoeSan after their divergence from other modern human populations.

  15. Data suggest regulatory interactions between major histocompatibility antigen HLA-C and killer cell Ig-like receptor (KIR) might promote Graft-versus-Leukemia effects following transplantation.

  16. Coengagement of inhibitory receptors, either KIR2DL1 or CD94-NKG2A, did not inhibit phosphorylation of Stat5 but inhibited selectively phosphorylation of Akt and S6 ribosomal protein.

  17. genetic association studies in Chinese Han population: Data suggest that the frequency of KIR2DL1 gene is increased in women with pre-eclampsia when homozygous HLA-C2 allele appears in the fetus.

  18. Array CGH showed a 95 Kb de novo duplication on chromosome 19q13.4 encompassing four killer cell immunoglobulin-like receptor (KIR) genes.

  19. These results revealed that ITIM phosphorylation is controlled by self-association of KIR and that His-36 serves as a gatekeeper to prevent unregulated signaling through KIR2DL1.

  20. C2 of KIR2DL1 is a novel risk factor, and homozygosity for C1 is a protective factor for childhood B-ALL

Pig (Porcine) Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) Interaktionspartner

  1. using porcine transcriptome data, both the novel inhibitory gene and the LILR were highly expressed in peripheral blood, while the single KIR gene, KIR2DL1, was either very poorly expressed or not at all. These observations are a prerequisite for improved understanding of immune cell functions in the pig and other species.

  2. The first and possibly only KIR gene, named KIR2DL1, in Sus scrofa was identified.

Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) Antigen-Profil

Protein Überblick

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response.

Genbezeichner und Symbole assoziert mit KIR2DL1

  • killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1 (KIR2DL1) Antikörper
  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 (KIR2DL1) Antikörper
  • CD158A Antikörper
  • KIR-K64 Antikörper
  • KIR221 Antikörper
  • NKAT Antikörper
  • NKAT1 Antikörper
  • p58.1 Antikörper

Bezeichner auf Proteinebene für KIR2DL1

CD158 antigen-like family member A , MHC class I NK cell receptor , NKAT-1 , killer Ig receptor , killer cell immunoglobulin-like receptor 2DL1 , killer inhibitory receptor 2-2-1 , natural killer-associated transcript 1 , p58 NK cell inhibitory receptor NKR-K6 , p58 NK receptor CL-42/47.11 , p58 killer cell inhibitory receptor KIR-K64 , p58 natural killer cell receptor clones CL-42/47.11 , p58.1 MHC class-I-specific NK receptor

GENE ID SPEZIES
3802 Homo sapiens
100127456 Sus scrofa
Ausgewählte Anbieter für anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) Antikörper
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