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IL32A encodes a member of the cytokine family. Zusätzlich bieten wir Ihnen Interleukin 32 alpha Antikörper (17) und Interleukin 32 alpha Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.
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In Kaposi sarcoma (KS) splicing ratio of the IL-32 (zeige IL32 ELISA Kits) isoforms showed IL-32gamma as the highest expressed isoform, followed by IL-32beta, in HIV-related KS cases compared with controls. Our data suggest a possible survival mechanism by the splicing of IL-32gamma to IL-32beta and also IL-6 (zeige IL6 ELISA Kits), IL-8 (zeige IL8 ELISA Kits), and CXCR1 (zeige CXCR1 ELISA Kits) signaling pathways to reverse the proapoptotic effect of the IL-32gamma isoform, leading to tumor cell survival and th...
Three single nucleotide polymorphisms (SNPs) (rs28372698, rs12934561, rs4786370) of the IL32 (zeige IL32 ELISA Kits) gene have been proposed as modifiers for different diseases. The present study found no significant differences in the genotypic frequencies between the patients and healthy controls and no relation to survival for any of the SNPs.
This study showed that the induction level of IL-32 (zeige IL32 ELISA Kits) was increased in chronic rhinosinusitis with nasal polyps compared to normal nasal mucosa and that LPS-induced IL-32 (zeige IL32 ELISA Kits) expression in nasal polyp-derived fibroblasts was regulated via the TLR4 (zeige TLR4 ELISA Kits)/JNK (zeige MAPK8 ELISA Kits)/AKT (zeige AKT1 ELISA Kits)/CREB (zeige CREB1 ELISA Kits) signaling pathway.
findings show that IL-32alpha acts on NK cells to inhibit IL-15 (zeige IL15 ELISA Kits)-mediated STAT5 (zeige STAT5A ELISA Kits) phosphorylation and to suppress their IL-15 (zeige IL15 ELISA Kits)-induced effector molecule expression and cytolytic capacity. IL-32alpha also acted on DCs by downregulating IL-15 (zeige IL15 ELISA Kits)-induced IL-18 (zeige IL18 ELISA Kits) production, an important cytokine in NK cell activity.
Thus, endogenous IL-32 (zeige IL32 ELISA Kits) is a crucial cytokine involved in the host defense against Leishmania parasites.
Study indicated the overexpression of IL-32 (zeige IL32 ELISA Kits) in induced sputum of smokers and chronic obstructive pulmonary disease (COPD (zeige ARCN1 ELISA Kits)) patients, which was correlated with smoking exposure index and the degree of airway obstruction. It demonstrated that IL-32 (zeige IL32 ELISA Kits) might play critical role in smokers with COPD (zeige ARCN1 ELISA Kits).
this study shows that IL-32 (zeige IL32 ELISA Kits) might be involved in the pathogenesis of hepatic fibrosis by inducing TIMP-1 (zeige TIMP1 ELISA Kits) expression
serum levels of IL-32 (zeige IL32 ELISA Kits) and TNF-alpha (zeige TNF ELISA Kits) may be diagnostic markers, and serum IL-29 (zeige IL29 ELISA Kits) levels may be associated with good prognosis in patients with gastric cancer
the importance of IL-32 (zeige IL32 ELISA Kits) polymorphism and mRNA expression in susceptibility and influence of survival status in lung cancer
These findings suggested that IL-18RAP rs917997, IL-32 (zeige IL32 ELISA Kits) rs2015620, IL-22 (zeige IL22 ELISA Kits) rs1179251, and interactions between these polymorphisms and H. pylori infection were associated with risks of gastric lesions
This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
, interleukin-32 eta
, interleukin-32 small
, interleukin-32 theta
, natural killer cell transcript 4
, natural killer cells protein 4
, tumor necrosis factor alpha-inducing factor