Interleukin 31 Receptor A Proteine (IL31RA)

The protein encoded by IL31RA belongs to the type I cytokine receptor family. Zusätzlich bieten wir Ihnen Interleukin 31 Receptor A Antikörper (55) und Interleukin 31 Receptor A Kits (10) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
IL31RA 133396 Q8NI17
IL31RA 218624 Q8K5B1
Ratte IL31RA IL31RA 688622  
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Showing 6 out of 13 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,749.58
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,749.58
Details
Human Cells Human His tag 50 μg Anmelden zum Anzeigen 14 bis 16 Tage
$285.35
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Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$749.00
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
$888.80
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IL31RA Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, , , , ,
Mouse (Murine)
,

Weitere Proteine zu Interleukin 31 Receptor A (IL31RA) Interaktionspartnern

Human Interleukin 31 Receptor A (IL31RA) Interaktionspartner

  1. The first demonstration of the involvement of the IL-31/IL-31R axis in cancer came from studies in patients with mycosis fungoides/Sezary syndrome, the most frequent, cutaneous T cell lymphoma. Tumor cells were shown to produce IL-31, whose serum levels correlated with pruritus intensity.

  2. The interleukin IL-31/IL-31receptor axis contributes to tumor growth in human follicular lymphoma.

  3. detected in keratinocytes and nerve fibers in the dermis of atopic dermatitis and in the neurons of normal dorsal root ganglia

  4. IL31RA is a functional receptor expressed by a small subpopulation of IL-31RA(+)/TRPV1(+)/TRPA1(+) neurons and is a critical neuroimmune link between TH2 cells and sensory nerves for the generation of T cell-mediated itch.

  5. IL-31 and IL-31RA are upregulated in patients with allergic rhinitis, and induce MUC5AC gene expression in human airway epithelial cells.

  6. IFN-gamma-induced IL-31RA upregulation in dermal microvascular endothelium is processed via JNK and PI3 kinase activation

  7. The identification of OSMR and IL31RA gene pathology provides an explanation of the high prevalence of primary cutaneous amyloidosis in Taiwan as well as new insight into disease pathophysiology.

  8. A novel type I cytokine receptor is expressed on monocytes, signals proliferation, and activates STAT-3 and STAT-5.

  9. GPL is a novel cytokine receptor related to GP130 and leukemia inhibitory factor receptor

  10. the molecular mechanisms underlying GPL-mediated signal transduction

  11. IL-31 receptor alpha expression in epidermal keratinocytes is modulated by cell differentiation and interferon gamma

  12. ). Binding of IL-31 to its receptor activates Jak/STAT, PI3K/AKT and MAPK pathways.[review]

Mouse (Murine) Interleukin 31 Receptor A (IL31RA) Interaktionspartner

  1. IL-31 upregulates IL-31RA expression in DRG neuron cell bodies, and cutaneous-injected IL-31-induced itching is enhanced by DRG IL-31RA expression in mice

  2. Anti-IL-31 receptor antibody is shown to be a potential therapeutic option for treating itch and dermatitis in mice

  3. IL31RA is a functional receptor expressed by a small subpopulation of IL-31RA(+)/TRPV1(+)/TRPA1(+) neurons and is a critical neuroimmune link between TH2 cells and sensory nerves for the generation of T cell-mediated itch.

  4. Gp130(757F/F) mice rapidly develop distal stomach tumors, with loss of SHP2/Erk/AP-1 transcriptional regulation exemplified by decreased TFF1 expression and increased STAT1/3 regulated genes such as Reg I.

  5. IL-31 receptor alpha signaling is a novel negative regulatory pathway that specifically limits T helper cell type 2 inflammation.

  6. these data provide the first evidence of a function for IL-31-IL-31R interactions in limiting the magnitude of type 2 inflammatory responses within the intestine.

Interleukin 31 Receptor A (IL31RA) Protein Überblick

Protein Überblick

The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Genbezeichner und Symbole assoziert mit IL31RA

  • interleukin 31 receptor A (IL31RA)
  • interleukin 31 receptor A (Il31ra)
  • CRL Protein
  • CRL3 Protein
  • GLM-R Protein
  • Glmr Protein
  • GPL Protein
  • hGLM-R Protein
  • IL-31RA Protein
  • IL31RA Protein
  • NR10 Protein
  • PLCA2 Protein
  • PRO21384 Protein

Bezeichner auf Proteinebene für IL31RA

interleukin 31 receptor A , gp130-like monocyte receptor , IL-31 receptor subunit alpha , IL-31R subunit alpha , class I cytokine receptor , cytokine receptor-like 3 , interleukin-31 receptor subunit alpha , soluble type I cytokine receptor CRL3 , zcytoR17 , IL-31R-alpha , IL-31RA , cytokine receptor NR10 , gp130-like receptor , interleukin 31RA , mGLM-R , novel cytokine receptor 10

GENE ID SPEZIES
471545 Pan troglodytes
487212 Canis lupus familiaris
522636 Bos taurus
133396 Homo sapiens
218624 Mus musculus
688622 Rattus norvegicus
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