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The protein encoded by IL22 is a cytokine that shares the sequence similarity with IL17. Zusätzlich bieten wir Ihnen Interleukin 22 Antikörper (302) und Interleukin 22 Kits (85) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 68 products:
Mouse (Murine) IL22 Protein expressed in Escherichia coli (E. coli) - ABIN988063
Ki, Park, Zheng, Morales-Ibanez, Kolls, Bataller, Gao: Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: role of signal transducer and activator of transcription 3. in Hepatology (Baltimore, Md.) 2010
IL22 plays a critical role in maintaining barrier homeostasis against intestinal pathogens and commensal bacteria, and, as a member of the IL10 (zeige IL10 Proteine) superfamily, is critically involved in inflammation [Review]
TARC (zeige CCL17 Proteine) production in HaCaT keratinocytes through the interaction between IL-22 and IL-22Ralpha facilitates T-cell migration in atopic dermatitis caused by house dust mites.
IL-22 was found to be higher in PP than in PPMS (p<0.05).
IL-22 is increased in patients with GCA (zeige NPR1 Proteine) and affects viability and gene expression of arterial cells, supporting a potential role in disease pathogenesis.
The binding of IL-22 to IL-22 receptor induces STAT3 (zeige STAT3 Proteine) activation. We investigated the effect of IL-22 on the expression in airway epithelial cells in vitro after the stimulation with an analog of viral double-stranded RNA. Treatment of cells with STAT3 (zeige STAT3 Proteine) siRNA abolished the effect of IL-22 on the upregulation of PD-L1 (zeige CD274 Proteine).
suggest that the human IL-22BP (zeige IL22RA2 Proteine) isoforms have distinct spatial and temporal roles and coordinately fine-tune IL-22-dependent STAT3 (zeige STAT3 Proteine) responses in tissues as a type of rheostat.
IL-18 (zeige IL18 Proteine) cooperates with IL-15 (zeige IL15 Proteine) to promote group 3 innate lymphoid cell (ILC3) proliferation and IL-22 production; describe an IL-18 (zeige IL18 Proteine)-induced, NF-kappaB (zeige NFKB1 Proteine)-mediated mechanism that regulates IL-22 in ILC3s; at steady-state, IL-18 (zeige IL18 Proteine) produced by dendritic cells mediates IL-22 production by ILC3s to help maintain normal tissue integrity
results reveal that IL-22 increases intestinal epithelial permeability by upregulating Claudin-2 (zeige CLDN2 Proteine) expression through the JAK (zeige JAK3 Proteine)/STAT (zeige STAT1 Proteine) pathway
High serum levels of IL-22 were positively rather than inversely associated with several cardiometabolic risk factors. However, these associations did not translate into an increased risk for type 2 diabetes.
mucosal-associated invariant T cells in the genital mucosa have a distinct IL-17 (zeige IL17A Proteine)/IL-22 profile and may have an important role in the immunological homeostasis and control of microbes at this site
Expression analysis of IL-22, IL-26 (zeige IL26 Proteine) and two IFN-gamma (zeige IFNG Proteine) genes suggests an active role of these genes in immune responses in fish.
this study shows that hepatocyte responses to IL-22 stimulation are reduced in hypoxic environments
Epithelial IL-23R (zeige IL23R Proteine) signaling enables protective IL-22 responses in experimental colitis.
We conclude that IL-22 has an important role in controlling S. aureus nasal colonization through distinct mechanisms, with IL-22 mediating its effect exclusively by inducing AMP (zeige TMPRSS5 Proteine) expression and controlling availability of staphylococcal ligands.
investigated the function of Card9 (zeige CARD9 Proteine)-mediated innate immunity in inflammation-associated colon carcinogenesis; report that Card9 (zeige CARD9 Proteine)-signaling drives the production of IL-1beta (zeige IL1B Proteine) within the damaged intestine and regulates the subsequent generation of IL-22 by group3 innate lymphoid cells, which promotes tumorigenesis via STAT3 (zeige STAT3 Proteine) activation within the transformed epithelium
these results demonstrate that IL-22 has a critical role in vaccine-induced protection against Helicobacter pylori
this study shows for the first time that a defect in IL-22 is involved in the acute exacerbation induced by non-typeable Haemophilus influenzae infection during experimental chronic obstructive pulmonary disease
hypoxic IL-22 upregulation is dependent on HIF-1alpha (zeige HIF1A Proteine)
Macrophage-derived IL-22 protects hepatocytes from ethanol-induced cell death. IL-22 downregulation is a new regulatory target of LPS (zeige TLR4 Proteine) in the pathogenesis of AH.
IL-22 inhibits acetaldehyde-induced hepatic stellate cells activation and proliferation, which may be related to nuclear translocation of Nrf2 (zeige NFE2L2 Proteine) and increased activity of the antioxidant axis Nrf2 (zeige NFE2L2 Proteine)-keap1 (zeige KEAP1 Proteine)-ARE.
SNPs in IFNG (zeige IFNG Proteine), IFNGR1 (zeige IFNGR1 Proteine) and R2, IL22, and IL22RA1 (zeige IL22RA1 Proteine) were analyzed for an association to Estimated breeding values for somatic cell score in Canadian Holstein bulls; no significant associations were found.
Study concludes that bovine gamma/delta T cells are important sources of IL-22 and suggest a role for this cytokine in regulating immune responses at mucosal surfaces, including the gut (zeige GUSB Proteine).
The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent.
IL-10-related T-cell-derived inducible factor
, IL-10-related T-cell-derived-inducible factor
, cytokine Zcyto18
, IL-TIF alpha
, ILTIF alpha
, interleukin 10-related T cell-derived inducible factor