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Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2.
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Human IL1F9 ELISA Kit für Sandwich ELISA - ABIN572390
Takahashi, Nishida, Shioya, Imaeda, Bamba, Inatomi, Shimizu, Kitoh, Andoh: Interleukin (IL)-1β Is a Strong Inducer of IL-36γ Expression in Human Colonic Myofibroblasts. in PLoS ONE 2015
IL-36-mediated IL-6 (zeige IL6 ELISA Kits) and CXCL8 (zeige IL8 ELISA Kits) production in human lung fibroblasts and bronchial epithelial cells may be involved in pulmonary inflammation especially caused by bacterial or viral infections.
IL-36gamma inhibits differentiation and induces inflammation of keratinocyte via Wnt (zeige WNT2 ELISA Kits) signaling pathway in psoriasis.
IL-36gamma-stimulated endothelial cells secrete the proinflammatory chemokines IL-8 (zeige IL8 ELISA Kits), CCL2 (zeige CCL2 ELISA Kits) and CCL20 (zeige CCL20 ELISA Kits).
skin injury increases IL-36gamma via the activation of TLR3 (zeige TLR3 ELISA Kits)-SLUG-VDR (zeige CYP27B1 ELISA Kits) axis and IL-36gamma induces REG3A (zeige REG3A ELISA Kits) to promote wound healing
Autocrine and Paracrine Regulation of Keratinocyte Proliferation through a Novel Nrf2 (zeige GABPA ELISA Kits)-IL-36gamma Pathway
IL-36gamma, a member of the IL-1 (zeige IL1A ELISA Kits) superfamily, is involved in host defense and contributes to proinflammatory responses and development of inflammatory diseases.
Study shows that plasma concentrations of IL-36alpha and IL-36gamma are overexpressed in active systemic lupus erythematosus patients and that IL-36alpha has a substantial pro-inflammatory effect through regulation of IL-6 (zeige IL6 ELISA Kits) and CXCL8 (zeige IL8 ELISA Kits) production.
IRF6 is likely to promote inflammation to P. gingivalis through its regulation of IL-36gamma.
Findings indicate that Interleukin (IL)-1beta (zeige IL1B ELISA Kits)-induced interleukin 36 gamma (IL-36gamma) expression is mediated by the activation of transcriptional factors, NF-kappaB (zeige NFKB1 ELISA Kits) p65 and AP-1 (c-jun (zeige JUN ELISA Kits)).
IL36G was identified as strong regulators of skin pathology in both lesional and non-lesional skin samples.
these findings reveal a fundamental contribution for the IL-36/IL-36R axis in regulating the Treg-Th9 cell balance with broad implications for Th cell-mediated disorders, such as inflammatory bowel diseases and particularly ulcerative colitis
Data presented herein shed further light on involvement of T-bet in innate immunity and suggest that IL-36gamma, besides IFNgamma, may contribute to functions of this transcription factor in immunopathology.
Interleukin-36 (zeige IL1F6 ELISA Kits) (IL-36) ligands require processing for full agonist (IL-36alpha, IL-36beta, and IL-36gamma) or antagonist (IL-36Ra) activity
A critical role of IL-36R (zeige IL1RL2 ELISA Kits) ligands in the interface between innate and adaptive immunity, leading to the stimulation of T helper responses.
Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2. Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response.
, IL-1 related protein 2
, IL-1-related protein 2
, interleukin 1 family, member 9
, interleukin 1-related protein 2
, interleukin-1 epsilon
, interleukin-1 family member 9
, interleukin-1 homolog 1
, interleukin-36 gamma