Interleukin 1 Family, Member 6 Proteine (IL1F6)

Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2. Zusätzlich bieten wir Ihnen Interleukin 1 Family, Member 6 Antikörper (83) und Interleukin 1 Family, Member 6 Kits (17) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte IL1F6 IL1F6 296541  
IL1F6 54448 Q9JLA2
IL1F6 27179 Q9UHA7
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Top Interleukin 1 Family, Member 6 Proteine auf antikoerper-online.de

Showing 10 out of 29 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,370.21
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,749.58
Details
Escherichia coli (E. coli) Human Unkonjugiert   10 μg Anmelden zum Anzeigen 10 bis 12 Tage
$216.43
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Escherichia coli (E. coli) Maus Unkonjugiert   10 μg Anmelden zum Anzeigen 10 bis 12 Tage
$222.28
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Escherichia coli (E. coli) Human Unkonjugiert   50 μg Anmelden zum Anzeigen 4 Days
$522.50
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Escherichia coli (E. coli) Human Unkonjugiert 50 μg Anmelden zum Anzeigen 14 bis 16 Tage
$440.65
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Escherichia coli (E. coli) Maus Unkonjugiert 50 μg Anmelden zum Anzeigen 14 bis 16 Tage
$440.65
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
$888.80
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Escherichia coli (E. coli) Human Unkonjugiert 20 μg Anmelden zum Anzeigen 3 bis 4 Tage
$75.00
Details

IL1F6 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine) ,

Human , ,
, ,

Weitere Proteine zu Interleukin 1 Family, Member 6 (IL1F6) Interaktionspartnern

Mouse (Murine) Interleukin 1 Family, Member 6 (IL1F6) Interaktionspartner

  1. The data identify a novel role for IL-36 signaling in colonic inflammation and indicate that the IL-36R pathway may represent a novel target for therapeutic intervention.

  2. IL-1 and IL-36 have roles as inflammatory mediators in pustular psoriasis in a mouse model

  3. IL-1alpha and IL-36alpha form a self-amplifying inflammatory loop in vivo that in patients with insufficient counter regulatory mechanisms may become hyper-engaged and/or chronic

  4. An essential role of C/EBPbeta in the regulation of the Il36A gene via the proximal half-CRE*C/EBP element in response to inflammatory stimuli.

  5. IL-36 promotes myeloid cell infiltration, activation, and inflammatory activity in skin

  6. IL-36alpha acts as a pro-inflammatory cytokine in the lungs independent of both IL-1alpha and IL-1beta.

  7. Interleukin-36 (IL-36) ligands require processing for full agonist (IL-36alpha, IL-36beta, and IL-36gamma) or antagonist (IL-36Ra) activity

  8. A critical role of IL-36R ligands in the interface between innate and adaptive immunity, leading to the stimulation of T helper responses.

  9. Transcripts for IL-1F5, -1F6, -1F8, and -1F9 are all significantly increased in the involved skin of bitransgenic mice compared with their monotransgenic controls.

  10. local overexpression related to the development of tubulointerstitial lesions

  11. IL-1F6 can be externalized via a stimulus-coupled mechanism comparable to that used by IL-1beta

Human Interleukin 1 Family, Member 6 (IL1F6) Interaktionspartner

  1. The authors report that, in Mycobacterium tuberculosis-infected macrophages, IL-36 signaling modulates cholesterol biosynthesis and efflux via LXR.

  2. serum IL-36alpha levels were higher in active systemic lupus erythematosus patients and correlated with disease activity and arthritis

  3. IL-36-mediated IL-6 and CXCL8 production in human lung fibroblasts and bronchial epithelial cells may be involved in pulmonary inflammation especially caused by bacterial or viral infections.

  4. With a focus on the skin as a target for microbial and viral invasion, the current knowledge of IL-36: IL-36alpha, IL-36beta and IL-36gamma, functions is reviewed. One physiological function of the IL-36smay be to counteract microbial immune evasion. [Review]

  5. Data suggest that interleukin-36alpha (IL-36alpha) plays an important role in the pathophysiology of inflammation and fibrosis in the pancreas via an autocrine function.

  6. The data identify a novel role for IL-36 signaling in colonic inflammation and indicate that the IL-36R pathway may represent a novel target for therapeutic intervention.

  7. IL-36a was displayed to be able to suppress the growth of epithelial ovarian cancer cells in our setting, which is suggestive of its druggable potential in curing the epithelial ovarian cancer and that upregulation of IL-36a was found to be capable of inhibiting the growth of epithelial ovarian cancer cells.

  8. Increased Expression of Interleukin-36 is associated with Inflammatory Bowel Disease.

  9. IL-36alpha acts as a pro-inflammatory cytokine at cartilage level, by increasing the expression of markers of inflammation and cartilage catabolism.

  10. Study shows that plasma concentrations of IL-36alpha and IL-36gamma are overexpressed in active systemic lupus erythematosus patients and that IL-36alpha has a substantial pro-inflammatory effect through regulation of IL-6 and CXCL8 production.

  11. increases maturation of monocyte-derived dendritic cells

  12. IL36A-IL36R axis is modulated in patients with primary Sjogren's syndrome.

  13. IL-36alpha was highly expressed in nearly half of all colorectal cancer patients. Low expression level of IL-36alpha correlated with larger tumor size and advanced cancer stage. Low expression of IL-36alpha resulted in a poor prognosis of colorectal cancer patients.

  14. IL-36 promotes myeloid cell infiltration, activation, and inflammatory activity in skin

  15. Results show that IL-36alpha expression may play a pivotal role in determining the prognosis of hepatocellular carcinoma (HCC).

  16. The novel cytokine interleukin-36alpha is expressed in psoriatic and rheumatoid arthritis synovium.

  17. Interleukin-36 (IL-36) ligands require processing for full agonist (IL-36alpha, IL-36beta, and IL-36gamma) or antagonist (IL-36Ra) activity

  18. Expression of IL-1F6 is increased in human plaque psoriasis skin and in the lesional skin of transgenic mice compared with monotransgenic littermates.

  19. A functional IL-6 polymorphism has been weakly associated with level of peak bone mineral density and the rate of forearm trabecular postmenopausal bone loss in a cohort of women.

  20. IL-1F6 and IL-1F8, in addition to IL-1F9, activate the pathway leading to NF-kappaB in an IL-1Rrp2-dependent manner in Jurkat cells

Interleukin 1 Family, Member 6 (IL1F6) Protein Überblick

Protein Überblick

Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2. Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response.

Genbezeichner und Symbole assoziert mit IL1F6

  • interleukin 36, alpha (Il36a)
  • interleukin 1 family, member 6 (epsilon) (IL1F6)
  • interleukin 36, alpha (IL36A)
  • interleukin 1 family, member 6 (Il1f6)
  • interleukin 36 alpha (IL36A)
  • FIL1 Protein
  • FIL1(EPSILON) Protein
  • FIL1E Protein
  • IL-1F6 Protein
  • IL-1H1 Protein
  • IL1(EPSILON) Protein
  • IL1F6 Protein
  • Il1f9 Protein
  • IL1RP2 Protein
  • Il36a Protein

Bezeichner auf Proteinebene für IL1F6

interleukin 1 family, member 6 , interleukin-1 family member 6 , interleukin 1 family, member 6 (epsilon) , interleukin 1 family, member 6 (epsilon)-like , FIL1 epsilon , Fil1epsilon , IL-1 epsilon , IL-1F6 , interleukin 1 family, member 9 , interleukin-1 epsilon , interleukin-1 homolog 1 , interleukin-36 alpha , IL-1F6 (FIL-1-epsilon) , interleukin 1, epsilon

GENE ID SPEZIES
296541 Rattus norvegicus
470486 Pan troglodytes
523429 Bos taurus
54448 Mus musculus
27179 Homo sapiens
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