Interferon-Induced Transmembrane Protein 1 Proteine (IFITM1)

IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Zusätzlich bieten wir Ihnen IFITM1 Antikörper (109) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte IFITM1 IFITM1 293618  
IFITM1 8519 P13164
IFITM1 68713 Q9D103
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Top IFITM1 Proteine auf antikoerper-online.de

Showing 6 out of 7 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$7,626.01
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$5,355.45
Details
Escherichia coli (E. coli) Human GST tag Interferon-Induced Transmembrane Protein 1 (IFITM1) (AA 1-36) protein (GST tag) 1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$1,842.50
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$547.80
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Wheat germ Human Unkonjugiert   10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$654.29
Details

IFITM1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Mouse (Murine)

Weitere Proteine zu Interferon-Induced Transmembrane Protein 1 (IFITM1) Interaktionspartnern

Human Interferon-Induced Transmembrane Protein 1 (IFITM1) Interaktionspartner

  1. Identification of three distinct mutations that converted IFITM1 or IFITM3 (zeige IFITM3 Proteine) from inhibitors to enhancers of MERS-CoV or SARS (zeige SARS Proteine)-CoV spike protein-mediated entry revealed key structural motifs or residues determining the biological activities of IFITM proteins.

  2. Epithelial-mesenchymal transition (EMT (zeige ITK Proteine)) signature was dysregulated by both loss and gain of function of IFITM1, which was partially reverted by Caveolin-1 (CAV1 (zeige CAV1 Proteine)).

  3. These results indicate that IFITM1 protein can restrict alphavirus infection by inhibiting viral fusion with cellular membranes.

  4. The transcriptional regulation of IFITM1, 2 and 3 expression.

  5. IFITM1 and IFITM3 (zeige IFITM3 Proteine) inhibit Zika virus infection early in the viral life cycle.

  6. IFITM1 suppression blocks proliferation and invasion of aromatase (zeige CYP19A1 Proteine) inhibitor-resistant breast cancer in vivo by JAK (zeige JAK3 Proteine)/STAT1 (zeige STAT1 Proteine)-mediated induction of p21 (zeige CDKN1A Proteine).

  7. Compared with CD10 (zeige MME Proteine), IFITM1 has superior performance distinguishing endometrial stroma of adenomyosis from mesenchyma surrounding invasive endometrial adenocarcinoma.

  8. Overexpression of IFITM1 is associated with Oral Squamous Cell Carcinomas.

  9. High expression of IFITM1 is associated with poor prognosis of colorectal cancer.

  10. These findings indicate that overexpression of IFITM1 enhances the aggressive phenotype of triple-negative SUM149 IBC cells and that this effect is dependent on STAT2 (zeige STAT2 Proteine)/BRG1 (zeige SMARCA4 Proteine) interaction.

Mouse (Murine) Interferon-Induced Transmembrane Protein 1 (IFITM1) Interaktionspartner

  1. the importance of the C-terminal region of IFITM1 in modulating the antiviral function through controlling protein subcellular localization.

  2. Palmitoylation of IFITM1 regulates protein stability by preventing proteasomal degradation, and modification of the nonconserved cysteine at the IFITM1 C terminus supports an intramembrane topology with implications for anti-influenza A virus activity.

  3. the fact that IFITM1 can function as a negative regulator of cell proliferation, and because the gene maps to chromosome band 11p15.5, previously associated with NSCLC, it is likely that IFITM1 in man has a key role in tumor formation

  4. Fragilis2 regulates epithelialization of the somites and paraxial mesoderm formation.

  5. The antiproliferative action of IFN-gamma (zeige IFNG Proteine) requires the induction of IFITM1.

IFITM1 Protein Überblick

Protein Überblick

IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53- dependent manner. Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.

Genbezeichner und Symbole assoziert mit IFITM1

  • interferon induced transmembrane protein 1 (Ifitm1)
  • interferon induced transmembrane protein 1 (IFITM1)
  • interferon induced transmembrane protein 1 (9-27) (IFITM1)
  • 9-27 Protein
  • 1110036C17Rik Protein
  • CD225 Protein
  • DSPA2a Protein
  • IFI17 Protein
  • LEU13 Protein
  • Mil-2 Protein
  • Mil2 Protein

Bezeichner auf Proteinebene für IFITM1

interferon-induced transmembrane protein 1 , interferon induced transmembrane protein 1 (9-27) , interferon induced transmembrane protein 1 , dispanin subfamily A member 2a , interferon-induced protein 17 , interferon-inducible protein 9-27 , leu-13 antigen , fragilis protein 2 , fragilis2 , ifitm-like protein 2 , interferon induced transmembrane protein 2 like , interferon-induced membrane protein Leu-13/9-27 , interferon-induced transmembrane protein 1 (9-27) , interferon-induced transmembrane protein 1 (9-27) isoform 1

GENE ID SPEZIES
293618 Rattus norvegicus
100455800 Pongo abelii
100526663 Pan troglodytes
8519 Homo sapiens
68713 Mus musculus
697687 Macaca mulatta
353510 Bos taurus
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