Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Not yet known..
Showing 2 out of 10 products:
IFI35 enhances proliferation of mesangial cells and is regulated by MBD2 (zeige DPEP2 ELISA Kits) in lupus nephritis.
Damage-associated molecular patterns (DAMP (zeige AMPH ELISA Kits)) are important mediators of innate immunity. Here the authors show that N-myc and STAT interactor (NMI (zeige NMI ELISA Kits)) and interferon-induced protein 35 (IFP35) act as DAMPs to promote inflammation by activating macrophages via the Toll-like receptor 4 (zeige TLR4 ELISA Kits) and NF-kappaB (zeige NFKB1 ELISA Kits) pathways.
Study found that TLR3 (zeige TLR3 ELISA Kits) signaling induces the expression of IFI35, and IFI35 negatively regulates IFN-beta (zeige IFNB1 ELISA Kits)-P-STAT1 (zeige STAT1 ELISA Kits)-RIG-I (zeige DDX58 ELISA Kits)-CXCL10 (zeige CXCL10 ELISA Kits)/CCL5 (zeige CCL5 ELISA Kits) axis in U373MG cells. This suggests that IFI35 expressed in astrocytes may play an important role in regulating the innate immune system in astrocytoma cells.
Activation of TLR3 (zeige TLR3 ELISA Kits) by poly IC induces the IFI35 expression in Mesangial Cells. Regional expression of IFI35 and its dysregulation may be involved in the pathogenesis of glomerular inflammation in CKD.
Trim21 (zeige TRIM21 ELISA Kits) regulates Nmi-IFI35 complex-mediated inhibition of innate antiviral response
Knockdown of IFP35 expression abolished pEGFP-N1-2C and pEGFP-N1-Nmi-induced activation of type I interferon (zeige IFNA ELISA Kits) promoters.
IFI35 negatively regulates RIG-I (zeige DDX58 ELISA Kits) antiviral signaling and supports vesicular stomatitis virus replication.
IRF-1 (zeige IRF1 ELISA Kits) also activates IFP35 expression in an IFN-gamma (zeige IFNG ELISA Kits)-inducible manner.
Dissociation of the IFN-induced protein IFP35 from NMI is a newly defined specific cytoplasmic event occurring during apoptosis.
The results provide a novel role of CKIP-1 (zeige PLEKHO1 ELISA Kits) in cytokine signaling response and the biochemical mechanism, by which two previously identified modulators IFP35 and Nmi are involved via interactions.
Not yet known.
interferon-induced 35 kDa protein
, interferon-induced protein 35
, IFP 35
, interferon-induced 35 kDa protein homolog