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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. Zusätzlich bieten wir Ihnen Integrator Complex Subunit 6 Antikörper (26) und Integrator Complex Subunit 6 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.
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DICE1 appears to be involved in prostate cancer progression rather than in the initiation of prostate cancer.
Findings demonstrate INTS6P1 and INTS6 exert the tumor suppressive roles through competing for oncomiR-17-5p.
In response to the DNA damage response, INTS3 (zeige INTS3 ELISA Kits)-hSSB1 (zeige SSBP1 ELISA Kits)-INTS6 complex relocates to the DNA damage sites.
Findings suggest that EBV encoded miR (zeige MLXIP ELISA Kits)-BART3* miRNA targets DICE1 tumor suppressor to promote cellular growth and transformation in nasopharyngeal cancer(NPC (zeige NPC1 ELISA Kits)).
Somatic mutations were identified in three patients (3/56, 5%), and one novel polymorphism was identified in 3% of ESCC patients (4/136) and 3% of healthy individuals (6/232). We conclude that DICE1 mutations occur in ESCC but are infrequent.
DICE1 has a growth-suppressing activity and interferes with anchorage-independent growth of IGF-IR transformed tumor cells dependent upon IGF-I (zeige IGF1 ELISA Kits) signaling
Our results are consistent with a novel role for Ints6 in restricting the vertebrate organizer to a dorsal domain in embryonic patterning.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). Three transcript variants encoding two different isoforms have been found for this gene.
DEAD box protein
, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26
, RNA helicase HDB
, protein deleted in cancer 1
, integrator complex subunit 6
, integrator complex subunit 6-like
, integrator complex subunit 6-B
, integrator complex subunit 6-A