Insulin-Like Growth Factor 2 MRNA Binding Protein 3 Proteine (IGF2BP3)

The protein encoded by IGF2BP3 is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. Zusätzlich bieten wir Ihnen Insulin-Like Growth Factor 2 MRNA Binding Protein 3 Antikörper (78) und Insulin-Like Growth Factor 2 MRNA Binding Protein 3 Kits (24) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
IGF2BP3 10643 O00425
Ratte IGF2BP3 IGF2BP3 312320  
IGF2BP3 140488 Q9CPN8
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Showing 5 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$338.33
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Escherichia coli (E. coli) Human T7 tag,His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$736.00
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Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Anmelden zum Anzeigen 16 Days
$284.90
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IGF2BP3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu Insulin-Like Growth Factor 2 MRNA Binding Protein 3 (IGF2BP3) Interaktionspartnern

Human Insulin-Like Growth Factor 2 MRNA Binding Protein 3 (IGF2BP3) Interaktionspartner

  1. Data show that insulin-like growth factor-II mRNA-binding protein 2 and 3 (IMP2 (zeige IMPA2 Proteine)/3)-miR (zeige MLXIP Proteine)-200a-progesterone receptor (zeige PGR Proteine) axis represents a double-negative feedback loop and serves as a new potential therapeutic target for the treatment of Triple-negative breast cancer (TNBC).

  2. THADA fusion is a mechanism of IGF2BP3 activation and IGF1R (zeige IGF1R Proteine) signaling in thyroid cancer.

  3. High expression of IMP3 in adult mature testicular teratomas supports their malignant nature.

  4. tubal secretory cells with IMP3 signatures showing growth advantage could potentially serve as a latent precancer biomarker for tubal or pelvic serous carcinomas in women.

  5. These results suggested that pancreatic carcinogenesis involves an increased IMP3 mRNA expression, and it may become valuable diagnostic and prognostic markers as well as potential therapeutic targets for pancreatic cancer.

  6. the combination of p16/IMP3 expression was found to improve the discrepant results between cervical cytologic and histologic diagnoses

  7. High IMP3 expression is associated with hepatocellular carcinoma.

  8. Our results strengthen the association of IMP3 with the regulation of epithelial to mesenchymal transition in breast cancers

  9. Post-transcriptional regulation of cyclins D1, D3 and G1 and proliferation of human cancer cells depend on IMP-3 nuclear localization.

  10. IMP3 upregulates HMGA2 mRNA by opposing its interaction with Ago2 (zeige EIF2C2 Proteine)/let-7.

Mouse (Murine) Insulin-Like Growth Factor 2 MRNA Binding Protein 3 (IGF2BP3) Interaktionspartner

  1. IGF2BP3 regulated transcripts via targeting elements within 3' untranslated regions (3'UTR)

Xenopus laevis Insulin-Like Growth Factor 2 MRNA Binding Protein 3 (IGF2BP3) Interaktionspartner

  1. Findings show that Vg1RBP is required for terminal arborization but not long-range axon navigation and suggest that Vg1RBP-regulated mRNA translation promotes synaptic complexity

  2. the motif binding proteins Vera and hnRNP I (zeige PTBP1 Proteine) have differing roles during Vg1-dependent mRNA localization

  3. Vg1RBP phosphorylation by Erk2 MAP kinase (zeige MAPK1 Proteine) correlates with the cortical release of Vg1 mRNA during meiotic maturation of Xenopus oocytes

Insulin-Like Growth Factor 2 MRNA Binding Protein 3 (IGF2BP3) Protein Überblick

Protein Überblick

The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.

Genbezeichner und Symbole assoziert mit IGF2BP3

  • insulin like growth factor 2 mRNA binding protein 3 (IGF2BP3)
  • insulin-like growth factor 2 mRNA binding protein 3 (Igf2bp3)
  • insulin like growth factor 2 mRNA binding protein 3 (igf2bp3)
  • insulin-like growth factor 2 mRNA binding protein 3 (igf2bp3)
  • insulin like growth factor 2 mRNA binding protein 3 (Igf2bp3)
  • insulin like growth factor 2 mRNA binding protein 3 L homeolog (igf2bp3.L)
  • 2610101N11Rik Protein
  • AA522010 Protein
  • Ab2-255 Protein
  • AL022933 Protein
  • AU045931 Protein
  • B3 Protein
  • CT98 Protein
  • dvr1rbp Protein
  • IGF2 mRNA-binding protein 3-A Protein
  • igf2bp3-a Protein
  • igf2bp3-b Protein
  • IMP Protein
  • imp-3 Protein
  • IMP-3-A Protein
  • imp3 Protein
  • koc1 Protein
  • Koc13 Protein
  • mimp3 Protein
  • Neilsen Protein
  • RGD1306512 Protein
  • vera Protein
  • vera-A Protein
  • Vg1 RBP-A Protein
  • Vg1-RBP Protein
  • vg1rbp Protein
  • vickz3 Protein
  • wu:fb79c12 Protein
  • wu:fe06h09 Protein
  • zVg1RBP Protein

Bezeichner auf Proteinebene für IGF2BP3

IGF II mRNA binding protein 3 , IGF-II mRNA-binding protein 3 , IGF2 mRNA-binding protein 3 , KH domain containing protein overexpressed in cancer , KH domain-containing protein overexpressed in cancer , VICKZ family member 3 , cancer/testis antigen 98 , hKOC , insulin-like growth factor 2 mRNA-binding protein 3 , insulin-like growth factor 2, binding protein 3 , insulin-like growth factor 2 mRNA binding protein 3 , insulin-like growth factor 2 mRNA-binding protein 3-like , mIMP-3 , IMP-3 , Vg1 RBP , decapentaplegic and Vg-related 1 RNA-binding protein , decapentaplegic and Vg-related 1, RNA binding protein , vg1 RNA-binding protein , vg1-RBP , 69 kDa RNA-binding protein A , IGF-II mRNA-binding protein 3-A , IGF2 mRNA-binding protein 3-A , IMP-3-A , KH domain-containing transcription factor B3-A , RNA-binding protein Vera-A , Trans-acting factor B3-A , VICKZ family member 3-A , VLE-binding protein A , Vg1 RNA binding protein Vera , Vg1 RNA binding protein variant D , Vg1 RNA-binding protein A , Vg1 localization element binding protein A , VgLE-binding and ER association protein A , insulin-like growth factor 2 mRNA-binding protein 3-A , trans-acting factor B3-A , vg1 RBP-A , vg1 RNA-binding protein A , vg1 localization element binding protein A , vgLE-binding and ER association protein A

GENE ID SPEZIES
10643 Homo sapiens
312320 Rattus norvegicus
482357 Canis lupus familiaris
539650 Bos taurus
549893 Xenopus (Silurana) tropicalis
704774 Macaca mulatta
744246 Pan troglodytes
100231176 Taeniopygia guttata
100394155 Callithrix jacchus
100602302 Nomascus leucogenys
140488 Mus musculus
420617 Gallus gallus
30967 Danio rerio
100735179 Cavia porcellus
394293 Xenopus laevis
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