anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase Complex-Associated Protein (IKBKAP) Antikörper

The protein encoded by IKBKAP is a scaffold protein and a regulator for 3 different kinases involved in proinflammatory signaling. Zusätzlich bieten wir Ihnen Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase Complex-Associated Protein Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
IKBKAP 8518 O95163
IKBKAP 140934 Q8VHU4
IKBKAP 230233 Q7TT37
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Top anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase Complex-Associated Protein Antikörper auf antikoerper-online.de

Showing 10 out of 86 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert ELISA, IHC, WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (35.64 KDa) . Dilution: 1:500~1000 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
€466.81
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Rind (Kuh) Kaninchen Unkonjugiert ELISA, IHC, IHC (p), WB Human Lung, Nerve (formalin-fixed, paraffin-embedded) stained with IKBKAP antibody ABIN214271 at 20 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-IKBKAP / IKAP antibody IHC of human lung, nerve. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
€428.32
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Human Maus Unkonjugiert IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to IKBKAP on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml] IKBKAP monoclonal antibody (M03), clone 6G9 Western Blot analysis of IKBKAP expression in HeLa . 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
€389.38
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Human Kaninchen Unkonjugiert WB Western Blot: IKBKAP Antibody [ABIN153156] - Analysis of IKBKAP in Interleukin-1-stimulated 293 cells using this antibody at 1:500 dilution. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
€370.00
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Human Kaninchen Unkonjugiert ICC, IF, WB Immunocytochemistry/Immunofluorescence: IKBKAP Antibody [NBP2-16936] - HeLa cells were fixed in iced-cold MeOH for 5 min. Green: IKBKAP protein stained by IKBKAP antibody, Internal diluted at 1:500. Blue: Hoechst 33343 staining. Western Blot: IKBKAP Antibody [NBP2-16936] - Sample (30 ug of whole cell lysate) A: HeLa B: HepG2 5% SDS PAGE gel, diluted at 1:1000. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
€457.50
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Human Maus Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
€475.37
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Human Kaninchen Unkonjugiert ICC, IHC, IHC (p), WB Human Prostate (formalin-fixed, paraffin-embedded) stained with IKBKAP antibody ABIN214497 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Testis (formalin-fixed, paraffin-embedded) stained with IKBKAP antibody ABIN214497 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
€428.32
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Human Kaninchen Unkonjugiert ICC, ELISA, WB   100 μg Anmelden zum Anzeigen 15 bis 19 Tage
€466.40
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Human Kaninchen Unkonjugiert WB Western Blot: IKBKAP Antibody [ABIN153157] - Analysis of IKBKAP in Interleukin-1-stimulated 293 cells using ABIN153157 at 1:500 dilution 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
€307.50
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Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of various cells, using IKBKAP antibody. 100 μL Anmelden zum Anzeigen 16 Days
€318.93
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Am meisten referenzierte anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase Complex-Associated Protein Antikörper

  1. Human Polyclonal IKBKAP Primary Antibody für ICC, ELISA - ABIN1002511 : Krappmann, Hatada, Tegethoff, Li, Klippel, Giese, Baeuerle, Scheidereit: The I kappa B kinase (IKK) complex is tripartite and contains IKK gamma but not IKAP as a regular component. in The Journal of biological chemistry 2000 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal IKBKAP Primary Antibody für IF, WB - ABIN541167 : Cohen, Henzel, Baeuerle: IKAP is a scaffold protein of the IkappaB kinase complex. in Nature 1998 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal IKBKAP Primary Antibody für IHC (p), ELISA - ABIN563666 : Lefler, Cohen, Kantor, Cheishvili, Even, Birger, Turetsky, Gil, Even-Ram, Aizenman, Bashir, Maayan, Razin, Reubinoff, Weil: Familial Dysautonomia (FD) Human Embryonic Stem Cell Derived PNS Neurons Reveal that Synaptic Vesicular and Neuronal Transport Genes Are Directly or Indirectly Affected by IKBKAP Downregulation. in PLoS ONE 2015 (PubMed)

Weitere Antikörper gegen Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase Complex-Associated Protein Interaktionspartner

Human Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase Complex-Associated Protein (IKBKAP) Interaktionspartner

  1. overexpression of miR-203a-3p leads to a decrease of NOVA1, counter-balanced by an increase of IKAP, supporting a potential interaction between NOVA1 and IKAP.

  2. IKAP might be a vesicular like protein that might be involved in neuronal transport in hESC derived PNS neurons

  3. The formation of the Elp1 dimer contributes to its stability in vitro and in vivo and is required for the assembly of human Elongator complexes.

  4. IKBKAP mRNA levels decreased during a familial dysautonomia crisis and returned to baseline after recovery. The cause-and-effect relationship is unclear.

  5. Phosphatidylserine increases IKBKAP levels in a humanized knock-in IKBKAP mouse model for Familial dysautonomia.

  6. Digoxin-mediated repression of SRSF3 expression plays a role in the digoxin-mediated inclusion of exon 20 in the IKBKAP transcript generated from the familial dysautonomia mutant allele.

  7. Combined treatment with epigallocatechin gallate and genistein synergistically upregulates wild-type IKBKAP-encoded RNA and protein levels in familial dysautonomia-derived cells.

  8. IKAP plays pleiotropic roles in both the peripheral and central nervous systems

  9. IKAP/hELP1 deficiency has an effect on gene expression in differentiating neuroblastoma cells, and possibly on familial dysautonomia

  10. IKK complex-associated protein deficiency upregulates the microtubule destabilizing protein SCG10 and, in parallel, disorganizes the cytoskeleton

  11. Phosphatidylserine increases IKBKAP levels in familial dysautonomia cells

  12. IKAP regulates contactin levels for appropriate cell-cell adhesion that could modulate neuronal growth of neurons during development

  13. IKAP is critical for the development of afferent baroreflex pathways and has therapeutic implications in the management of these patients.

  14. IKBKAP is a candidate gene for Hirschsprung's disease and was mapped to chromosome 9q31 locus.

  15. novel role for the I kappa B kinase complex-associated protein (IKAP) in the regulation of activation of the mammalian stress response via the c-Jun N-terminal kinase (JNK)-signaling pathway

  16. Genetics of familial dysautonomia; tissue-specific expression of a splicing mutation (REVIEW)

  17. Tissue-specific reduction in splicing efficiency of this protein is due to the major mutation associated with familial dysautonomia.

  18. The study results suggest that the polymorphisms in the coding region of the IKAP gene are unlikely to contribute to atopic disease risk in the Czech population.

  19. whereas IKBKAP (Elongator) is recruited to both target and nontarget genes, only target genes display histone H3 hypoacetylation and progressively lower RNAPII density through the coding region in familial dysautonomia cells

  20. Neurodevelopmental disease familial dysautonomia (FD)caused by a single-base change in the 5' splice site (5'ss) of intron 20 in the IKBKAP gene (c.2204+6T>C).

Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase Complex-Associated Protein (IKBKAP) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a scaffold protein and a regulator for 3 different kinases involved in proinflammatory signaling. This encoded protein can bind NF-kappa-B-inducing kinase (NIK) and IKKs through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia.

Genbezeichner und Symbole assoziert mit IKBKAP

  • elongator complex protein 1 (ELP1) Antikörper
  • elongator complex protein 1 (Elp1) Antikörper
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein (IKBKAP) Antikörper
  • ielongator complex protein 1 S homeolog (elp1.S) Antikörper
  • elongator complex protein 1 (elp1) Antikörper
  • inhibitor of kappa light polypeptide enhancer in B cells, kinase complex-associated protein (Ikbkap) Antikörper
  • 3110040G09Rik Antikörper
  • 6030413P05 Antikörper
  • C78473 Antikörper
  • DKFZp469N1415 Antikörper
  • DYS Antikörper
  • Elp1 Antikörper
  • FD Antikörper
  • IKAP Antikörper
  • Ikbkap Antikörper
  • IKI3 Antikörper
  • TOT1 Antikörper

Bezeichner auf Proteinebene für IKBKAP

IKK complex-associated protein , elongator acetyltransferase complex subunit 1 , elongator complex protein 1 , ikappaB kinase complex-associated protein , p150 , ELP1 , inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein , inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein , putative elongator complex protein 1 , IKK-complex-associated protein IKAP , IKAP , Elongator complex protein 1-like protein

GENE ID SPEZIES
8518 Homo sapiens
140934 Rattus norvegicus
427375 Gallus gallus
473014 Pan troglodytes
612455 Canis lupus familiaris
735009 Xenopus laevis
100170442 Xenopus (Silurana) tropicalis
100171912 Pongo abelii
100229335 Taeniopygia guttata
100560669 Anolis carolinensis
100585002 Nomascus leucogenys
230233 Mus musculus
100009360 Oryctolagus cuniculus
100728587 Cavia porcellus
100157586 Sus scrofa
100053999 Equus caballus
505465 Bos taurus
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