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The protein encoded by ID3 is a helix-loop-helix (HLH) protein that can form heterodimers with other HLH proteins. Zusätzlich bieten wir Ihnen Inhibitor of DNA Binding 3, Dominant Negative Helix-Loop-Helix Protein Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.
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Mouse (Murine) Monoclonal ID3 Primary Antibody für WB - ABIN967547
Cooper, Brady, Bilia, Iscove, Quesenberry: Expression of the Id family helix-loop-helix regulators during growth and development in the hematopoietic system. in Blood 1997
Show all 7 Pubmed References
Human Monoclonal ID3 Primary Antibody für IF, ELISA - ABIN516798
Chen, Forootan, Gosney, Forootan, Ke: Increased expression of Id1 and Id3 promotes tumorigenicity by enhancing angiogenesis and suppressing apoptosis in small cell lung cancer. in Genes & cancer 2014
Human Monoclonal ID3 Primary Antibody für ICC, IF - ABIN152941
Berthier-Vergnes, Kharbili, de la Fouchardière, Pointecouteau, Verrando, Wierinckx, Lachuer, Le Naour, Lamartine: Gene expression profiles of human melanoma cells with different invasive potential reveal TSPAN8 as a novel mediator of invasion. in British journal of cancer 2011
Cow (Bovine) Polyclonal ID3 Primary Antibody für WB - ABIN2779573
Tsuchiya, Okaji, Tsuno, Sakurai, Tsuchiya, Kawai, Yazawa, Asakage, Yamada, Yoneyama, Kitayama, Osada, Watanabe, Tokunaga, Takahashi, Nagawa: Targeting Id1 and Id3 inhibits peritoneal metastasis of gastric cancer. in Cancer science 2005
Immunohistochemical detection of inhibitor of DNA binding 3 mutational variants in mature aggressive B-cell lymphoma.
The results of the present study revealed that overexpression of Id3 may serve as a novel strategy for inhibiting cisplatinsensitive lung cancer.
Results show that ID1 (zeige ID1 Antikörper), ID3 and IGJ (zeige IGJ Antikörper) genes are highly expressed in adult B-ALL and correlate with poor prognosis in Hispanic patients.
Upon Id3 transfection, A549 cells displayed decreased migratory and invasive capabilities, however, co-transfection of miRId3 and Id3 into A549 cells reversed the Id3-induced inhibitions of migratory and invasive capabilities.
Inhibitor of differentiation 4 (ID4 (zeige ID4 Antikörper)) acts as an inhibitor of ID-1 (zeige ID1 Antikörper), -2 and -3 and promotes basic helix loop helix (bHLH) E47 (zeige TCF3 Antikörper) DNA binding and transcriptional activity.
ID3 has a role in the acquisition of molecular stem cell-like signature in microvascular endothelial cells
our data provide evidence that ID3 may play a critical role in regulating vascular endothelial cell survival and development of microvascular lesions induced by persistent environmental pollutants such as PCB153.
ID3 plays a potential role in the underlying regulatory mechanisms of metabolic health in human obesity. [Review]
Epigenetic changes in ID3, in combination with experiences of maltreatment, may confer risk for depression in children.
Data indicate association of inhibitor of differentiation 3 (ID3) single nucleotide polymorphism rs11574 directly with coronary artery pathology.
Mechanistic analysis indicated that E47 (zeige TCF3 Antikörper) activated expression of the transcription factor Spi-B (zeige SPIB Antikörper) and the suppressor of cytokine signaling 3 (SOCS3 (zeige SOCS3 Antikörper)), which both downregulated Foxp3 (zeige FOXP3 Antikörper) expression. These findings demonstrate that the balance of Id3 and E47 (zeige TCF3 Antikörper) controls the maintenance of Foxp3 (zeige FOXP3 Antikörper) expression in Treg cells and, thus, contributes to Treg cell plasticity.
The present study provides additional support for roles for ID3 in the etiology of depression following early adversity.
Our work identifies a distinct premalignant state and multiple tumorigenic pathways caused by loss of function of Id2 and Id3
down-regulation of Id3 in B cells is essential for releasing E2A (zeige TCF3 Antikörper) and E2-2 (zeige TCF4 Antikörper), which in a redundant manner are required for antigen-induced B cell differentiation.
Results found that Id3 expression is high in follicular B lineage cells but declines in germinal center (GC) cells. However, during the GC reaction, Id3 levels decline to activate the expression of genes encoding signaling components that mediate B cell receptor- and or cytokine receptor (zeige LEPR Antikörper)-mediated signaling to promote the differentiation of GC B (zeige NPR2 Antikörper) cells.
These results identify Id3 as the BMP-2 (zeige BMP2 Antikörper)-induced transcriptional regulator, promoting adult NSPC differentiation into astrocytes upon CNS injury
Inflammation-induced S100A8 (zeige S100A8 Antikörper) promotes colorectal tumorigenesis by acting upstream to activate the Akt1 (zeige AKT1 Antikörper)-Smad5 (zeige SMAD5 Antikörper)-Id3 axis.
Data show that enforced expression of inhibitor of differentiation protein Id3 specifically increased the persistence of Cd244 (zeige CD244 Antikörper) protein 2B4 (zeige CD244 Antikörper)(+) virus-specific CD8 (zeige CD8A Antikörper)(+) T cells.
ID2/3 are crucial regulators of the adaptive antioxidant-mitochondrial response that promotes beta cell survival during oxidative stress through a novel link to the NFE2L2 (zeige NFE2L2 Antikörper)-small MAF (zeige MAF Antikörper) pathway.
Enhanced IL-13 (zeige IL13 Antikörper) production by T cells can play a causative role in the exocrinopathy observed in Id3 knockout mice.
Data revealed that expression of DNA binding inhibitor 3 (zeige PPP1R11 Antikörper), early B cell factor 2 (zeige EBF2 Antikörper), Ebf3 (zeige EBF3 Antikörper), Iroquois related homeobox 1 (zeige IRX1 Antikörper), Kruppel-like factor 7 , mab-21-like 1 (zeige MAB21L1 Antikörper) , fatty acid binding protein 7 (zeige FABP7 Antikörper) and stathmin-like 4 (zeige STMN4 Antikörper),were enriched in the diencephalon of zebrafish.
expression of id3 in zebrafish embryo
Results provide evidence that the helix-loop-helix factor Id3 mediates the mitogenic effect of hyperlipemic sera and ox-LDL in VSMC via inhibition of p21cip1 (zeige CDKN1A Antikörper) expression, subsequently increasing DNA synthesis and proliferation
The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with other HLH proteins. However, the encoded protein lacks a basic DNA-binding domain and therefore inhibits the DNA binding of any HLH protein with which it interacts.
DNA-binding protein inhibitor ID-3
, ID-like protein inhibitor HLH 1R21
, class B basic helix-loop-helix protein 25
, helix-loop-helix protein HEIR-1
, ID-like protein inhibitor HLH 462
, Inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
, helix-loop-helix protein
, inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
, olfactory receptor 136-6
, olfactory receptor I-D3
, olfactory receptor MOR136-6
, DNA-binding protein inhibitor ID-3-B
, Inhibitor of DNA binding 3-B