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The protein encoded by ID1 is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. Zusätzlich bieten wir Ihnen ID1 Proteine (7) und ID1 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.
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Human Monoclonal ID1 Primary Antibody für WB - ABIN967545
Cooper, Brady, Bilia, Iscove, Quesenberry: Expression of the Id family helix-loop-helix regulators during growth and development in the hematopoietic system. in Blood 1997
Show all 8 Pubmed References
Human Monoclonal ID1 Primary Antibody für ELISA, WB - ABIN561409
Chen, Forootan, Gosney, Forootan, Ke: Increased expression of Id1 and Id3 promotes tumorigenicity by enhancing angiogenesis and suppressing apoptosis in small cell lung cancer. in Genes & cancer 2014
Human Monoclonal ID1 Primary Antibody für IF, ELISA - ABIN561410
Phi, Choi, Lim, Lee, Wang, Park, Kim: ID3 contributes to cerebrospinal fluid seeding and poor prognosis in medulloblastoma. in BMC cancer 2013
Gain and loss of id1 function in vivo demonstrated that Id1 promotes stem cell quiescence. The increased id1 expression observed in neural stem cells in response to injury appeared independent of inflammatory signals.
a loss of CULLIN3 represents a common signaling node for controlling the activity of intracellular WNT (zeige WNT2 Antikörper) and SHH (zeige SHH Antikörper) signaling pathways mediated by ID1
These results reveal a E2F1 (zeige E2F1 Antikörper)/miR-17-92/ENH1 (zeige PDLIM5 Antikörper)/Id1 regulatory axis during myogenesis.
Id1 enables both Lewis lung carcinoma cells and the host microenvironment for an effective liver colonization.
adipose tissue-specific overexpression of Id1 causes age-associated and high-fat diet-induced obesity in mice. Id1 suppresses BAT (zeige BAAT Antikörper) thermogenesis by binding to and suppressing PGC1alpha transcriptional activity. Lack of Id1 increases beige (zeige LYST Antikörper) gene and Ucp1 (zeige UCP1 Antikörper) expression in the WAT in response to cold exposure. Furthermore, brown-like differentiation is increased in Id1-deficient mouse embryonic fibroblasts.
If Gfi1 (zeige ZNF163 Antikörper) levels fall below a threshold, Id1 expression increases and renders E2A (zeige TCF3 Antikörper) unable to function, which prevents hematopoietic progenitors from engaging along the B lymphoid lineage
Id1 may promote cell cycle progression of endothelial progenitor cells (EPCs), and that Wnt2 (zeige WNT2 Antikörper) may be important in Id1 regulation of the cell cycle of EPCs.
Differential role of Id1 in MLL (zeige MLL Antikörper)-AF9 (zeige MLLT3 Antikörper)-driven leukemia based on cell of origin
Collectively, our results suggest that ENH1 plays an important role in the activation of myogenesis through the repression of Id2 activity.
Data indicate that upregulation of E2-2 (zeige TCF4 Antikörper) protein markedly attenuated the inhibitor of DNA-binding 1 (ID1)-mediated increase in endothelial progenitor cells (EPCs) proliferation and migration.
our results strongly suggest that Usp1 (zeige USP1 Antikörper) is involved in the regulation of centrosome duplication, at least in part via ID1, and Usp1 (zeige USP1 Antikörper) may exert its oncogenic activity, partially through inducing centrosome abnormality.
Id1 enables lung cancer liver colonization by activating an epithelial mesenchymal transformation program in tumor cells and establishing the pre-metastatic niche.
High ID1 expression is associated with breast cancer.
ID1 expression impacts the sensitivity of colon cancer cells to 5-FU and may be considered as a potential predictive marker in colorectal carcinoma treatment.
Reducing ID1 gene expression reduces metastatic spread of salivary gland neoplasms.
High ID-1 expression is associated with colorectal carcinoma.
ID1 expression was positively related to drug resistance of EGFR (zeige EGFR Antikörper)-TKI in non-small cell lung cancer.
MVD was determined by immunohistochemistry, and the expressions of mRNA and protein of inhibitor of differentiation-1 (ID1) and vascular endothelial growth factor (VEGF) were detected in gastric cancer.
ID1 down-regulation induced parallel changes in the IGF and AKT (zeige AKT1 Antikörper) pathways. The crosstalk of these pathways may enhance malignant phenotypes in salivary gland cancer.
Results show that ID1, ID3 (zeige ID3 Antikörper) and IGJ (zeige IGJ Antikörper) genes are highly expressed in adult B-ALL and correlate with poor prognosis in Hispanic patients.
The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene.
inhibitor of DNA binding 1
, DNA-binding protein inhibitor id-1
, inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
, DNA-binding protein inhibitor ID-1
, inhibitor of DNA binding 6
, Inhibitor of DNA binding 1 helix-loop-helix protein (splice varaiation)
, Inhibitor of DNA binding 1, helix-loop-helix protein (splice variation)
, class B basic helix-loop-helix protein 24
, dJ857M17.1.2 (inhibitor of DNA binding 1, dominant negative helix-loop-helix protein)
, inhibitor of differentiation 1
, helix-loop-helix protein