anti-Importin 8 (IPO8) Antikörper

The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. Zusätzlich bieten wir Ihnen Importin 8 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
IPO8 10526 O15397
IPO8 320727 Q7TMY7
IPO8    
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Top anti-Importin 8 Antikörper auf antikoerper-online.de

Showing 10 out of 34 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Hund Kaninchen Unkonjugiert WB WB Suggested Anti-IPO8 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Kidney 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert IHC, ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Kaninchen Unkonjugiert ICC, IF, SimWes, WB Western Blot: Importin-8 Antibody [NBP2-24751] - Analysis of Importin-8 in HeLa lysate in the 1) absence and 2) presence of immunizing peptide using Importin-8 antibody at 1 ug/ml. Simple Western: Importin-8 Antibody [NBP2-24751] - Simple Western lane view shows a specific band for Importin-8 in 0.5 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$444.19
Details
Maus Kaninchen Unkonjugiert ICC, IHC, WB DAB staining on IHC-P; Samples: Mouse Stomach Tissue 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$324.00
Details
Human Ziege Unkonjugiert IHC (p), IHC, ELISA Immunohistochemistry-Paraffin: Importin-8 Antibody [ABIN249599] - Staining of Human Tonsil. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining. Similar results were obtained after antigen retrieval at pH9. (4ug/ml) 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Human Kaninchen Unkonjugiert ICC, IF, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Kaninchen Unkonjugiert WB Western Blot: Importin-8 Antibody [ABIN4090904] - Whole cell lysate from HeLa (5, 15 and 50 ug) and 293T (T; 50 ug) cells. Antibody used at for WB at 0.4 ug/ml. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Human Ziege Unkonjugiert ELISA 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: Importin-8 Antibody [NBP1-87879] - Staining of human gall bladder shows cytoplasmic positivity with a granular pattern in glandular cells. Immunohistochemistry-Paraffin: Importin-8 Antibody  - Staining of human kidney shows moderate granular cytoplasmic positivity in tubular cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Ziege Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details

IPO8 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Importin 8 Antikörper

  1. Human Polyclonal Importin 8 Primary Antibody für ICC, IF - ABIN4325788 : Wu, Wang, Young, Lai, Li: Proteome-wide identification of novel binding partners to the oncogenic fusion gene protein, NPM-ALK, using tandem affinity purification and mass spectrometry. in The American journal of pathology 2009 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal Importin 8 Primary Antibody für IHC (p), IHC - ABIN249599 : Görlich, Dabrowski, Bischoff, Kutay, Bork, Hartmann, Prehn, Izaurralde: A novel class of RanGTP binding proteins. in The Journal of cell biology 1997 (PubMed)

Weitere Antikörper gegen Importin 8 Interaktionspartner

Human Importin 8 (IPO8) Interaktionspartner

  1. the findings of the present study provided novel insights into the control of IPO8 transcription, and may enhance understanding regarding RUNX2 (zeige RUNX2 Antikörper) regulatory mechanisms in osteoblast differentiation, bone development, and degenerative bone disease.

  2. Our studies also suggest that nuclear entry is important for the prooncogenic activity of eIF4E (zeige EIF4E Antikörper), at least in this context. These findings position nuclear trafficking of eIF4E (zeige EIF4E Antikörper) as a critical step in its regulation and position the importin 8-eIF4E (zeige EIF4E Antikörper) complex as a novel therapeutic target.

  3. importin alpha8 functions as a cNLS receptor with distinct cargo specificity, and that heterodimerization by importin alpha8 is a novel regulatory mode of cNLS binding, in addition to the autoinhibitory regulation by the importin beta (zeige KPNB1 Antikörper) binding domain.

  4. Knockdown of IPO8 reduced the amount of nuclear p65 (zeige GORASP1 Antikörper) following TNF (zeige TNF Antikörper) stimulation. IPO8 binding to p65 (zeige GORASP1 Antikörper) is NLS (zeige ALDH1A2 Antikörper) independent.

  5. TGF-beta (zeige TGFB1 Antikörper)-induced and basal state spontaneous nuclear import of Smad4 (zeige SMAD4 Antikörper) require importin 7 (zeige IPO7 Antikörper) and 8.

  6. IPO8 is the most accurate reference gene for clinical lung specimens.

  7. Study provides evidence that Imp8 is required for cytoplasmic miRNA-guided gene silencing and affects nuclear localization of Ago proteins.

Mouse (Murine) Importin 8 (IPO8) Interaktionspartner

  1. Importin 8 plays a critical role in mediating the cytoplasm-to-nucleus transport of mature miRNAs. IPO8-mediated nuclear transport of mature miRNAs is also dependent on the association of IPO8 with the Argonaute 2 (zeige EIF2C2 Antikörper) complex.

Importin 8 (IPO8) Antigen-Profil

Protein Überblick

The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit anti-Importin 8 (IPO8) Antikörper

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Bezeichner auf Proteinebene für anti-Importin 8 (IPO8) Antikörper

importin 8 , importin-8 , RAN binding protein 8 , imp8 , ran-binding protein 8 , ATP-binding cassette, sub-family C (CFTR/MRP), member 10 , oocyte maturation 1

GENE ID SPEZIES
418142 Gallus gallus
473395 Pan troglodytes
523408 Bos taurus
555520 Danio rerio
612863 Canis lupus familiaris
10526 Homo sapiens
320727 Mus musculus
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