Hyaluronan Binding Protein 2 Proteine (HABP2)

The protein encoded by HABP2 is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. Zusätzlich bieten wir Ihnen HABP2 Antikörper (54) und HABP2 Kits (10) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
HABP2 3026 Q14520
HABP2 292126 Q6L711
HABP2 226243 Q8K0D2
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Top HABP2 Proteine auf antikoerper-online.de

Showing 9 out of 17 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Anmelden zum Anzeigen 11 Days
$341.00
Details
Human Cells Human His tag   50 μg Anmelden zum Anzeigen 4 Days
$600.88
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Human Cells Human His tag   10 μg Anmelden zum Anzeigen 15 bis 16 Tage
$300.00
Details
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,759.17
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,759.17
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$640.00
Details

HABP2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Rat (Rattus)

Mouse (Murine)

Weitere Proteine zu Hyaluronan Binding Protein 2 (HABP2) Interaktionspartnern

Human Hyaluronan Binding Protein 2 (HABP2) Interaktionspartner

  1. The presence of the noninheritable V600E BRAF (zeige BRAF Proteine) mutation in this family supports Knudson's "double-hit" hypothesis for cancer development and suggests the involvement of more than 1 gene in the clinical expression of familial nonmedullary thyroid carcinoma.

  2. The MI-SNP and MII-SNP FSAP gene polymorphisms were not predictive or prognostic biomarkers for coronary artery diseaseor its main risk factors.

  3. NETs bind to FSAP, but do not activate pro-FSAP unless histones are released from NETs by DNAse (zeige DNASE2 Proteine). This activation of FSAP is likely to be important in diminishing the cytotoxic effect of histones, thus limiting the damaging effect of NETosis.

  4. Regulation of gene expression by FSAP in vascular smooth muscle/endothelial cells accounts for its vasculo-regulatory properties.

  5. The extent of CAC (zeige CA2 Proteine) in women is positively associated with total FSAP, but negatively associated with the specific activity of FSAP suggesting that FSAP may play a role in the evolution of CVD in women.

  6. Report peptide substrates used in determining substrate specificity of Factor VII activating protease.

  7. Two of 20 probands from families with history of PTC (zeige F9 Proteine) and breast carcinoma (BC) were evaluated by whole exome sequencing (WES) revealing HABP2 p.G534E.

  8. No significant association was found between rs11196288 and early-onset ischemic stroke, large artery atherosclerotic stroke, or small vessel disease stroke. rs11196288 presented significant effect on late-onset SVD (zeige KCNJ13 Proteine) stroke susceptibility in the older population.

  9. study on a wide series of familial non-medullary thyroid cancers indicates that the HABP2(G534E) variant is frequent, but does not segregate with the disease

  10. Letter: G534E variant in HABP2 is not associated with non-medullary thyroid cancer in the Spanish population.

Mouse (Murine) Hyaluronan Binding Protein 2 (HABP2) Interaktionspartner

  1. FSAP deficiency causes an increase in CCL2 (zeige CCL2 Proteine) expression and CCL2 (zeige CCL2 Proteine)-mediated infiltration of leukocytes into the injured vessel

  2. the promoter activity, which could phenocopy changes in Habp2 mRNA in response to TGF-beta (zeige TGFB1 Proteine), was found to be located in the 177-bp region upstream of the transcription start site, and this region did not contain any SMAD (zeige SMAD1 Proteine) binding sites.

  3. Lack of endogenous FSAP impaired the formation of stable, occlusive thrombi in mice.

  4. Results show that the lack of FSAP in mice worsens the outcome of stroke; in the absence of FSAP there was a stronger inflammatory response and lower cell survival due to insufficient activation of the PI3K/AKT (zeige AKT1 Proteine) pathway

  5. Lower FSAP expression is associated with enhanced liver fibrosis and inflammation in patients with chronic hepatic disorders and murine experimental liver injury.

  6. Data indicate that FSAP mediates proteolytic cleavage and activation of bone morphogenetic protein-2 (BMP-2 (zeige BMP2 Proteine)).

  7. Hyaluronic acid binding protein 2 (HABP2) negatively regulates vascular integrity via activation of protease-activated receptor/RhoA (zeige RHOA Proteine)/Rho kinase (zeige ROCK2 Proteine) signaling. It represents a potential therapeutic target for syndromes of increased vascular permeability.

HABP2 Protein Überblick

Protein Überblick

The protein encoded by this gene is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. The encoded protein is synthesized as a single chain, but then undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This protease is known to cleave urinary plasminogen activator, coagulation factor VII, and the alpha and beta chains of fibrinogen, but not prothrombin, plasminogen, or the gamma chain of fibrinogen. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit HABP2

  • hyaluronan binding protein 2 (HABP2)
  • hyaluronan binding protein 2 (habp2)
  • hyaluronan binding protein 2 (Habp2)
  • hyaluronic acid binding protein 2 (Habp2)
  • AI035669 Protein
  • Fsap Protein
  • Habp Protein
  • habp2 Protein
  • HGFAL Protein
  • Phbp Protein

Bezeichner auf Proteinebene für HABP2

hyaluronan binding protein 2 , hyaluronan-binding protein 2-like , factor VII activating protein , factor VII-activating protease , factor seven-activating protease , hepatocyte growth factor activator-like protein , hyaluronan-binding protein 2 , hyaluronic acid binding protein 2 , plasma hyaluronan binding protein , plasma hyaluronan-binding protein , hyaduronic acid-binding protein 2

GENE ID SPEZIES
423898 Gallus gallus
450744 Pan troglodytes
477822 Canis lupus familiaris
548376 Xenopus (Silurana) tropicalis
697495 Macaca mulatta
100068293 Equus caballus
100223786 Taeniopygia guttata
100407842 Callithrix jacchus
100461891 Pongo abelii
100472238 Ailuropoda melanoleuca
100591352 Nomascus leucogenys
3026 Homo sapiens
507993 Bos taurus
292126 Rattus norvegicus
226243 Mus musculus
Ausgewählte Anbieter für HABP2 Proteine (HABP2)
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