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Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Zusätzlich bieten wir Ihnen HtrA Serine Peptidase 3 Antikörper (29) und HtrA Serine Peptidase 3 Kits (16) und viele weitere Produktgruppen zu diesem Protein an.
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Human HTRA3 Protein expressed in Insect Cells - ABIN807971
Dynon, Heng, Puryer, Li, Walton, Endo, Nie: HtrA3 as an early marker for preeclampsia: specific monoclonal antibodies and sensitive high-throughput assays for serum screening. in PLoS ONE 2012
Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (By similarity). May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization (By similarity).
Trypsin-like serine protease
, HtrA serine peptidase 3
, probable serine protease HTRA3-like
, high-temperature requirement factor A3
, pregnancy-related serine protease
, probable serine protease HTRA3
, serine protease HTRA3
, toll-associated serine protease