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In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Zusätzlich bieten wir Ihnen HOXA4 Antikörper (77) und viele weitere Produktgruppen zu diesem Protein an.
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HOXA4/HOXB3 (zeige HOXB3 Proteine) gene expression-based risk score may be useful for prognostic risk stratification and warrants prospective validation in HGSOC patients.
Overexpression of HOXA4 and HOXA9 (zeige HOXA9 Proteine) contributes to self-renewal and overpopulation of stem cells in colorectal cancers.
HOXA4 increases short-term repopulation to higher levels than HOXB4 (zeige HOXB4 Proteine), which may involve Notch (zeige NOTCH1 Proteine) signaling to induce self-renewal of primitive hematopoietic cells
The NK AML (zeige RUNX1 Proteine) patients with NPM1 (zeige NPM1 Proteine) mutations exhibited elevated HOXA4 methylation and expression levels of HOXA5 (zeige HOXA5 Proteine) and MEIS1 (zeige MEIS1 Proteine) compared with the NPM1 (zeige NPM1 Proteine) wildtype patients.
promoter hypermethylation of HOXA4 gene could be an epigenetic mechanism mediating IM resistance in CML patients.
HOXA4 showed nuclear & perinuclear staining in endothelial & smooth muscle cells in aorta. Spatial variation in expression in human aortas persisted into adulthood. Downregulation of HOXA4 expression was associated with abdominal aortic aneurysm.
Studies suggest that HOXA4, HOXA5 (zeige HOXA5 Proteine) and HOXB4 (zeige HOXB4 Proteine) provide the spatial information needed to restrict the response to signals from the notochord, and not up regulated in pancreatic cancer.
Results confirm that HOXA4 inhibits cell motility, show that it suppresses cell spreading and filopodia formation while enhancing cell-cell adhesion, and suggest a role for beta1 integrin in mediating these changes.
upregulated significantly in acute myeloid leukemia (zeige BCL11A Proteine) patients with a white blood cell count higher than 30 x 10(9)/L cells.
aberrant DNA methylation (zeige HELLS Proteine) may have a major role in the control of HOXA4 gene expression in chronic lymphocytic leukemia
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation.
, Hox-1.4-like protein
, homeo box A4
, homeobox protein Hox-1.4
, homeobox protein Hox-1D
, homeobox protein Hox-A4
, homeobox protein MH-3
, homeobox A4
, Homeobox protein Hox-A4
, homeobox protein XlHbox4b
, Homeobox gene A4
, homeobox A4-like
, homeobox protein Hox-A4-like
, homeobox protein R2