High Affinity Choline Transporter (ChT) ELISA Kits

Choline is a direct precursor of acetylcholine (ACh), a neurotransmitter of the central and peripheral nervous system that regulates a variety of autonomic, cognitive, and motor functions. Zusätzlich bieten wir Ihnen High Affinity Choline Transporter Antikörper (36) und High Affinity Choline Transporter Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
ChT 60482 Q9GZV3
ChT 63993 Q8BGY9
ChT 85426 Q9JMD7
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top High Affinity Choline Transporter ELISA Kits auf antikoerper-online.de

Showing 4 out of 9 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Ratte 28 pg/mL 78.12 pg/mL - 5000 pg/mL   96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$800.00
Details
Human 0057 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 17 Tage
$908.41
Details
Maus 0055 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 17 Tage
$929.89
Details
Human < 0.188 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests Anmelden zum Anzeigen 11 bis 18 Tage
$810.17
Details

Weitere ELISA Kits für High Affinity Choline Transporter Interaktionspartner

Human High Affinity Choline Transporter (ChT) Interaktionspartner

  1. Lack of association between SLC5A7 polymorphisms and Tourette syndrome in a Chinese Han population

  2. Here we describe an autosomal recessive presynaptic congenital myasthenic syndrome presenting with a broad clinical phenotype due to homozygous SLC5a7 missense mutations. Phenotype ranges from classical presentation of a congenital myasthenic syndrome in one patient (p.Pro210Leu), to severe neurodevelopmental delay with brain atrophy (p.Ser94Arg) and extend the clinical outcomes to infantile lethality (p.Val112Glu).

  3. Impaired Presynaptic High-Affinity Choline Transporter Causes a Congenital Myasthenic Syndrome with Episodic Apnea: this study broadens the clinical spectrum of human diseases resulting from reduced CHT activity and highlights the complexity of cholinergic metabolism at the synapse

  4. These data show that acute exposure of depolarized cells to insulin is coupled to transiently increased levels of CHT proteins at the cell surface, and that this is attenuated by chronic insulin exposure.

  5. This study demonstrated a specific impairment in cognitive control associated with the Ile89Val polymorphism of SLC5A7.

  6. This mini-review discusses structural requirements for both organic cationic transporters OCT1 and OCT2 versus the blood-brain barrier choline transporter (BBBCHT) are discussed and compared.

  7. [review] The critical role of CHT in maintaining cholinergic transmission indicates that it could be a target for therapeutic intervention to promote acetylcholine synthesis, the accomplishment of which has not been adequately addressed.

  8. In transgenic animals with a heterozygous deletion of the choline transporter there is impairment in performing sustained attention tasks.

  9. CHT1 forms a homo-oligomer on the cell surface in cultured cells.

  10. Our findings compel consideration of mutations in SLC5A7 or its functional partners in relation to unexplained motor neuronopathies.

  11. Polymorphic variation in the CHT1 gene can predict early, subclinical measures of carotid atherosclerosis.

  12. Nedd4-2 mediated ubiquitination regulates the cell surface expression of CHT1 in HEK293 cells.

  13. overexpressed ChAT enhanced transcription of the CHT1 gene but not the VACHT gene

  14. The colocalisation of CHT1 immunoreactivity with VAChT immunoreactivity in cholinergic enteric nerves in the human bowel thus suggests that CHT1 represents another marker of cholinergic nerves.

  15. Results describe the identification and functional characterization of a single nucleotide polymorphism in the high affinity choline transporter (CHT1) gene.

  16. high-affinity choline transporter, choline transporter 1, in nerve fibers and epithelial cells in the human and rat skin supporting the pivotal role of this transporter in both the neuronal and non-neuronal cholinergic system of the skin.

  17. CHT1 binds to Par-4 and inhibits choline uptake when its incorporation is reduced on the cell surface

  18. CHT1 variation is related to differences in a distributed corticolimbic circuitry mediating behavioral and physiologic arousal.

  19. The charge/choline ratio of hCHT varies from 10e/choline at -80 mV to 3e/choline at -20 mV. Choline uptake & choline-induced current are Na+ & Cl- dependent. External protons reduce hCHT current, transport, & binding with a similar pKa of 7.4.

Mouse (Murine) High Affinity Choline Transporter (ChT) Interaktionspartner

  1. Our findings suggest that CHT protein levels preferentially impact the capacity for ACh release afforded by mobilization of reserve pool vesicles

  2. These data provide evidence for an epithelium-independent non-vesicular, non-quantal ACh release in the mouse trachea involving low-affinity choline transporters.

  3. bacterial artificial chromosome CHT mice thus represent a novel tool to examine both the positive and negative impact of constitutively elevated cholinergic signaling capacity

  4. These findings reveal compensatory mechanisms that, in the context of moderate cognitive challenges, can overcome the performance deficits expected from the significantly reduced ACh capacity of CHT+/- cholinergic terminals.

  5. CHT association with cholesterol-rich rafts is critical for its function

  6. This study showed that a constitutive loss of CHT expression in hemizygous mice leads to a significant reduction in basal extracellular dopamine levels in the nucleus accumbens.

  7. This study demonistrated that CHT support for neuromuscular signaling involves contributions to ACh synthesis as well as cholinergic synaptic vesicle availability.

  8. CHT1 knockout mice have tachycardia and hypertension at rest.

  9. CHT1 binds to Par-4 and inhibits choline uptake when its incorporation is reduced on the cell surface

  10. CHT is an essential and regulated presynaptic component of cholinergic signaling

  11. CHT1 was expressed early in CNS development, predominantly in the regions containing cholinergic neurons. NGF AND BMP4 increased CHT mRNA accumulation in primary septal cultures.

  12. Choline transporter hemizygosity results in adequate baseline acetylcholine stores, sufficient to sustain many phenotypes, but normal sensitivities to physical and/or pharmacological challenge require full cholinergic signaling capacity.

  13. Interestingly, although CHT is expressed predominantly in cholinergic cells, its regulation appears to be distinct from that of the cholinergic locus.

  14. Real-time RT-PCR revealed significant decreases in CHT1 mRNA in the lung of sensitized and allergen challenged animals.

  15. adaptor proteins have important functions for CHT trafficking in neuronal cells

  16. Synapses persist for at least 2-3 months without postsynaptic activity; however, the presynaptic terminals lack high-affinity choline transporters (CHTs), and as a result, they are quickly depleted of transmitter.

High Affinity Choline Transporter (ChT) Antigen-Profil

Beschreibung des Gens

Choline is a direct precursor of acetylcholine (ACh), a neurotransmitter of the central and peripheral nervous system that regulates a variety of autonomic, cognitive, and motor functions. SLC5A7 is a Na(+)- and Cl(-)- dependent high-affinity transporter that mediates the uptake of choline for acetylcholine synthesis in cholinergic neurons (Apparsundaram et al., 2000

Genbezeichner und Symbole assoziert mit ChT

  • solute carrier family 5 member 7 (SLC5A7) Antikörper
  • solute carrier family 5 (choline transporter), member 7 (Slc5a7) Antikörper
  • solute carrier family 5 member 7 (Slc5a7) Antikörper
  • CHT Antikörper
  • Cht1 Antikörper
  • hCHT Antikörper
  • HMN7A Antikörper

Bezeichner auf Proteinebene für ChT

hemicholinium-3-sensitive choline transporter , high affinity choline transporter 1 , high affinity choline transporter; hemicholinium-3-sensitive choline transporter , solute carrier family 5 (choline transporter), member 7 , solute carrier family 5 member 7 , CHT , solute carrier family 5, member 7

GENE ID SPEZIES
60482 Homo sapiens
414870 Gallus gallus
481311 Canis lupus familiaris
512311 Bos taurus
63993 Mus musculus
85426 Rattus norvegicus
100733609 Cavia porcellus
100060334 Equus caballus
Ausgewählte Anbieter für High Affinity Choline Transporter (ChT) ELISA Kits
Haben Sie etwas anderes gesucht?