anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) Antikörper

HNRNPK belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). Zusätzlich bieten wir Ihnen Heterogeneous Nuclear Ribonucleoprotein K Kits (30) und Heterogeneous Nuclear Ribonucleoprotein K Proteine (15) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
HNRNPK 3190 P61978
HNRNPK 117282 P61980
HNRNPK 15387 P61979
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Top anti-Heterogeneous Nuclear Ribonucleoprotein K Antikörper auf antikoerper-online.de

Showing 10 out of 165 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-HNRPK Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded H1299 xenograft, using hnRNP K, antibody at 1:100 dilution. ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed A431, using hnRNP K, antibody at 1:200 dilution. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-HNRPK Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Huhn Kaninchen Unkonjugiert IC, IF, WB Immunofluorescent analysis of hnRNP K (pS284) staining in Raw264.7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of hnRNP K (pS284) expression in MCF7 EGF-treated (A), Raw264.7 EGF-treated (B), H9C2 EGF-treated (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$575.00
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from NIH-3T3 cells treated with EGF 200ng/ml 30', using hnRNP K (Phospho-Ser284) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from K562/A549/HT-29 cells, using hnRNP K (Ab-284) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: hnRNP K Antibody [NBP1-30975] - Sample (50 ug of whole cell lysate) A: Mouse brain 10% SDS PAGE; antibody diluted at 1:1000. Immunohistochemistry-Paraffin: hnRNP K Antibody [NBP1-30975] - Paraffin-embedded H1299 xenograft, using antibody at 1:100 dilution. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$514.63
Details
Human Kaninchen Unkonjugiert IF, IHC, IP, RIP, WB Western blot analysis of extracts of various cell lines, using HNRNPK antibody. 100 μL Anmelden zum Anzeigen 16 Days
$334.02
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of anti-HNRPK Antibody (N-term) (ABIN389377) in 293 cell line lysates (35 µg/lane). HNRPK(arrow) was detected using the purified polyclonal antibody. Western blot analysis of anti-HNRPK Antibody (N-term) (ABIN389377) in mouse brain tissue lysates (35 µg/lane). HNRPK(arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details

HNRNPK Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-Heterogeneous Nuclear Ribonucleoprotein K Antikörper

  1. Mouse (Murine) Monoclonal HNRNPK Primary Antibody für ChIP, ELISA - ABIN108575 : Matunis, Michael, Dreyfuss: Characterization and primary structure of the poly(C)-binding heterogeneous nuclear ribonucleoprotein complex K protein. in Molecular and cellular biology 1992 (PubMed)
    Show all 3 Pubmed References

  2. Mouse (Murine) Monoclonal HNRNPK Primary Antibody für ChIP, ELISA - ABIN108576 : Blanchette, Fuentes Medel, Gardner: Cell-type-specific and developmental regulation of heterogeneous nuclear ribonucleoprotein K mRNA in the rat nervous system. in Gene expression patterns : GEP 2006 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal HNRNPK Primary Antibody für IF, WB - ABIN516590 : Proepper, Steinestel, Schmeisser, Heinrich, Steinestel, Bockmann, Liebau, Boeckers: Heterogeneous nuclear ribonucleoprotein k interacts with Abi-1 at postsynaptic sites and modulates dendritic spine morphology. in PLoS ONE 2011 (PubMed)

  4. Chicken Monoclonal HNRNPK Primary Antibody für IHC (p), WB - ABIN2474083 : Bomsztyk, Van Seuningen, Suzuki, Denisenko, Ostrowski: Diverse molecular interactions of the hnRNP K protein. in FEBS letters 1997 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Heterogeneous Nuclear Ribonucleoprotein K Interaktionspartner

Human Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) Interaktionspartner

  1. we discovered that hnRNPK plays an important role in bladder cancer, suggesting that it is a potential prognostic marker and a promising target for treating bladder cancer.

  2. The hnRNPK positively regulates the level of prostate tumor overexpressed 1 (zeige PTOV1 Antikörper)-antisense 1 which harbors five binding sites for miR (zeige MLXIP Antikörper)-1207-5p. The knockdown of hnRNPK or PTOV1 (zeige PTOV1 Antikörper)-AS1 (zeige PTGDR Antikörper) increased the enrichment of heme oxygenase-1 (zeige HMOX1 Antikörper) mRNA in miR (zeige MLXIP Antikörper)-1207-5p-mediated miRNA-induced silencing complex and thus suppressed the expression of heme oxygenase-1 (zeige HMOX1 Antikörper).

  3. High HNRNPK expression is associated with pancreatic cancer.

  4. Down-regulation of DAB2IP (zeige DAB2IP Antikörper) correlated negatively with hnRNPK and MMP2 (zeige MMP2 Antikörper) expressions in CRC (zeige CALR Antikörper) tissues. In conclusion, our study elucidates a novel mechanism of the DAB2IP (zeige DAB2IP Antikörper)/hnRNPK/MMP2 (zeige MMP2 Antikörper) axis in the regulation of CRC (zeige CALR Antikörper) invasion and metastasis, which may be a potential therapeutic target.

  5. Tumor cells bearing a p53 (zeige TP53 Antikörper) mutation showed increased damage levels and delayed repair. Knockdown of hnRNPK applied simultaneously with irradiation reduced colony-forming ability and survival of tumor cells. Taken together, our data shows that hnRNPK is a relevant modifier of DNA damage repair and tumor cell survival. We therefore recommend further studies to evaluate the potential of hnRNPK as a drug target for improvement

  6. Data suggest that hnRNPK plays role in heat shock response of cells by regulating HSF1; hnRNPK inhibits HSF1 activity, resulting in reduced expression of HSP27 and HSP70 mRNAs; hnRNPK also down-regulates binding of HSF1 to heat shock response element. (hnRNPK = heterogeneous-nuclear ribonucleoprotein K; HSF1 = heat shock transcription factor 1; HSP = heat-shock protein)

  7. KRAS-mutant colorectal carcinoma shows intrinsic radioresistance along with rapid upregulation of hnRNP K in response to ionizing radiation that can effectively be targeted by MEK (zeige MAP2K1 Antikörper) inhibition.

  8. Nujiangexathone A, a novel compound from Garcinia nujiangensis, down-regulates hnRNPK levels in cervical tumor cells, inducing cell cycle arrest.

  9. Our study also suggests that loss of function variants in HNRNPK should be considered as a molecular basis for patients with Kabuki-like syndrome

  10. these findings support a critical role for hnRNP K in the regulation of autophagy in drug-resistant leukemia cells, and this RNP (zeige RNPC3 Antikörper) is therefore a potential target of clinical drug-resistance treatment.

Xenopus laevis Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) Interaktionspartner

  1. A novel role for the nuclear localization signal in regulating hnRNP K protein stability in vivo has been described.

  2. a previously unidentified function of phosphorylation at this phylogenetically conserved site and implicates hnRNPK as an intracellular molecular target of ERK (zeige MAPK1 Antikörper)-mediated signaling in axon outgrowth.

  3. hnRNP K is essential for successful optic axon regeneration via a novel post-transcriptional regulatory pathway.

  4. A crucial role is reported for hnrpk in axon development in Xenoops laevis.

Mouse (Murine) Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) Interaktionspartner

  1. This is the first study revealing the presence of a parallel increase in expressions of FTO (zeige FTO Antikörper) and HNRNPK proteins. This increase may codictate the metabolic changes occurring in the cell and may attribute a significance to HNRNPK in FTO (zeige FTO Antikörper)-associated transformations.

  2. hnRNPK recruits PCGF3 (zeige PCGF3 Antikörper)/5-PRC1 (zeige PRC1 Antikörper) to the Xist RNA B-repeat to establish polycomb (zeige CBX2 Antikörper)-mediated chromosomal silencing.

  3. the beneficial actions of insulin (zeige INS Antikörper) in diabetic nephropathy appear to be mediated, in part, by suppressing renal Nrf2 (zeige NFE2L2 Antikörper) and Agt (zeige AGXT Antikörper) gene transcription and preventing Nrf2 (zeige NFE2L2 Antikörper) stimulation of Agt (zeige AGXT Antikörper) expression via hnRNP F (zeige HNRNPF Antikörper)/K.

  4. the cytoplasmic hnRNPK interacts with GSK3beta and regulates its function.

  5. Data implicate hnRNPK in the development of hematological disorders and suggest hnRNPK acts as a tumor suppressor.

  6. These findings functionally integrate K17 (zeige KRT17 Antikörper), hnRNP K, and gene expression along with RSK (zeige RPS6KA1 Antikörper) and CXCR3 (zeige CXCR3 Antikörper) signaling in a keratinocyte-autonomous axis and provide a potential basis for their implication in tumorigenesis

  7. Nova haploinsufficient mice had spontaneous epilepsy

  8. HnRNP K-3' UTR (zeige UTS2R Antikörper) complex inhibits TAK1 (zeige NR2C2 Antikörper) mRNA translation.

  9. hnRNP-K regulates extracellular matrix, cell motility, and angiogenesis pathways. Involvement of the selected genes (Cck (zeige CCK Antikörper), Mmp-3 (zeige MMP3 Antikörper), Ptgs2 (zeige PTGS2 Antikörper), and Ctgf (zeige CTGF Antikörper)) and pathways was validated by gene-specific expression analysis

  10. HNRNPK affects production of the essential NEAT1_2 isoform by negatively regulating its 3'-end polyadenylation by arresting CFIm (zeige CPSF6 Antikörper) complex binding near NEAT1_1's alternative polyadenylation site.

Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) Antigen-Profil

Protein Überblick

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference\; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized.

Genbezeichner und Symbole assoziert mit HNRNPK

  • heterogeneous nuclear ribonucleoprotein K (HNRNPK) Antikörper
  • heterogeneous nuclear ribonucleoprotein K (Hnrnpk) Antikörper
  • heterogeneous nuclear ribonucleoprotein K S homeolog (hnrnpk.S) Antikörper
  • heterogeneous nuclear ribonucleoprotein K (hnrnpk) Antikörper
  • heterogeneous nuclear ribonucleoprotein K (LOC5565718) Antikörper
  • heterogeneous nuclear ribonucleoprotein k (CpipJ_CPIJ000130) Antikörper
  • heterogeneous nuclear ribonucleoprotein K (NGK_p0004) Antikörper
  • Csbp Antikörper
  • hnrpk Antikörper
  • KBBP Antikörper
  • MGC75642 Antikörper
  • NOVA Antikörper
  • TUNP Antikörper
  • wu:fb37h02 Antikörper
  • wu:fi34c04 Antikörper
  • zgc:66162 Antikörper

Bezeichner auf Proteinebene für HNRNPK

dC-stretch binding protein , transformation upregulated nuclear protein , dC stretch-binding protein , hnRNP K , heterogeneous nuclear ribonucleoprotein K , heterogeneous nuclear ribonucleoprotein k , hnRNP-K protein , heterogeneous nuclear ribonucleoprotein K-like

GENE ID SPEZIES
3190 Homo sapiens
117282 Rattus norvegicus
380255 Xenopus laevis
394952 Xenopus (Silurana) tropicalis
406267 Danio rerio
464554 Pan troglodytes
528135 Bos taurus
5565718 Aedes aegypti
6030937 Culex quinquefasciatus
6446928 Neisseria gonorrhoeae NCCP11945
100008849 Oryctolagus cuniculus
100173769 Pongo abelii
15387 Mus musculus
427458 Gallus gallus
100052735 Equus caballus
100390554 Callithrix jacchus
100601168 Nomascus leucogenys
100855638 Canis lupus familiaris
100861302 Capra hircus
101117560 Ovis aries
100622191 Sus scrofa
100729110 Cavia porcellus
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