Heterogeneous Nuclear Ribonucleoprotein H1 (H) Proteine (HNRNPH1)

HNRNPH1 encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). Zusätzlich bieten wir Ihnen HNRNPH1 Antikörper (95) und HNRNPH1 Kits (14) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
HNRNPH1 3187 P31943
HNRNPH1 59013 O35737
HNRNPH1 140931 Q8VHV7
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Top HNRNPH1 Proteine auf antikoerper-online.de

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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,626.73
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,626.73
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
$888.80
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,259.67
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HNRNPH1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1) Interaktionspartnern

Human Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1) Interaktionspartner

  1. serum exosomal hnRNPH1 mRNA levels in hepatocellular carcinoma (HCC) patients were remarkably higher than in the other groups; exosomal hnRNPH1 mRNA levels in HCC patients were associated with the Child-Pugh classification, portal vein tumor emboli, lymph node metastasis, TNM stage and overall survival; findings suggested that serum exosomal hnRNPH1 mRNA could be an effective marker for HCC in high HBV prevalence areas

  2. Together, these data implicate C9ORF72 GGGGCC expansion-mediated sequestration of hnRNP H as a significant contributor to neurodegeneration in C9 amyotrophic lateral sclerosis (ALS) and frontotemporal dementia.

  3. High HNRNPH1 expression is associated with castration-resistant prostate cancer.

  4. hnRNP H binds to two specific G-runs in exon 5a of ACHE and activates the distal alternative 3 splice site (ss) between exons 5a and 5b. Furthermore, hnRNP H competes for binding of CstF64 to the overlapping binding sites in exon 5a, and suppresses the selection of a cryptic polyadenylation site, which additionally ensures transcription of the distal 3 ss required for the generation of AChET isoform.

  5. The different alternative transcript variants of HNRNPH1 exhibited different expression changes during tumorigenesis. Its mRNA and protein were overexpressed in esophageal squamous cell carcinoma and associated with poorer differentiation of tumor cells.

  6. Our findings define novel roles for hnRNPH1 as a putative oncogene, splicing factor, and an auxiliary AR coregulator.

  7. Global splicing analysis with RNA-seq revealed that exons carrying the hnRNP H-binding GGGGG motif are predisposed to be skipped compared to those carrying the SRSF1-binding GGAGG motif in both human and mouse brains.

  8. vRSF3 and hnRNP H1 are the first splicing factors identified which regulate the production of these functionally distinct HER2 splice variants and therefore maybe important for the regulation of HER2 signaling.

  9. In pediatric T-acute lymphoblastic leukemia, we have identified 2 RNA processing genes, that is, HNRNPH1/5q35 and DDX3X/Xp11.3 as new MLLT10 fusion partners.

  10. These results support a working hypothesis that a late viral protein HPV16 L1, which is down regulated by hnRNP H early in the viral life cycle may provide an auto-regulatory positive feedback loop that allows the rapid production of HPV capsid proteins through suppression of the function of hnRNP H at the late stage of the viral life cycle.

  11. The REST N exon is a very versatile sequence with a complex array of splicing signals, and its activation in H69 cells depends on the relative amounts of hnRNP H and U2AF65.

  12. These results suggest that increased level of hnRNP-H and PDIA3 expression in Dengue virus infected THP1 cells assist in the viral replication by suppressing the TNF-alpha production.

  13. hnRNPH activity appears to be involved in the pathogenesis and progression of malignant gliomas as the centre of a splicing oncogenic switch

  14. spatial interactions of hnRNPH1, NF45, and C14orf166 with HCVc174 likely modulate HCV or cellular functions during acute and chronic HCV infection

  15. Insight on the crucial role of hnRNP H1 in the regulation of the alternative splicing of the rpL3 gene.

  16. Nuclear heterogeneous nuclear ribonucleo-protein H expression was related to survival in colorectal cancer.

  17. altered function of hnRNP H1/H2 in tumor cells is a novel determinant of aberrant thymidine phosphorylase splicing thereby resulting in acquired chemoresistance to TP-activated fluoropyrimidine anticancer drugs.

  18. the G-stretches within exon 9B regulate RAGE alternative splicing via interaction with hnRNP H

  19. working model in which rpL3 recruits hnRNP H1 and, through cooperation with other splicing factors, promotes selection of the alternative splice site

  20. Results suggest that hnRNP H and F are nuclear shuttling proteins whose posttranslational modifications may alter interaction with transportin 1, nuclear localization, and hence function.

Mouse (Murine) Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1) Interaktionspartner

  1. These results define a novel contribution of Hnrnph1 to neurobehavioral dysfunction associated with dopaminergic neurotransmission.

  2. hnRNP C and hnRNP H bind to the 3'-UTR of the circadian clock gene Period 2 (mPer2).

  3. genome wide analysis of splicing events and gene expression regulated by hnRNPH/F in oligodendrocytes

  4. The hnRNP H1 can function as repressors of MOR translation dependent on the M4 sequence.

  5. hnRNPH activity appears to be involved in the pathogenesis and progression of malignant gliomas as the centre of a splicing oncogenic switch

HNRNPH1 Protein Überblick

Protein Überblick

This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described

Genbezeichner und Symbole assoziert mit HNRNPH1

  • heterogeneous nuclear ribonucleoprotein H1 (HNRNPH1)
  • heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2)
  • heterogeneous nuclear ribonucleoprotein H1 S homeolog (hnrnph1.S)
  • heterogeneous nuclear ribonucleoprotein H1 L homeolog (hnrnph1.L)
  • heterogeneous nuclear ribonucleoprotein H1 (hnrnph1)
  • heterogeneous nuclear ribonucleoprotein H1 (Hnrnph1)
  • AI642080 Protein
  • E430005G16Rik Protein
  • Hnrnph Protein
  • HNRNPH1 Protein
  • hnrnph2 Protein
  • Hnrph Protein
  • Hnrph1 Protein
  • hnrph2 Protein
  • MGC69543 Protein
  • MGC78776 Protein
  • MGC80081 Protein
  • MGC130700 Protein
  • zgc:77712 Protein

Bezeichner auf Proteinebene für HNRNPH1

heterogeneous nuclear ribonucleoprotein H , heterogeneous nuclear ribonucleoprotein H1 , heterogeneous nuclear ribonucleoprotein H1-like protein , heterogeneous nuclear ribonucleoprotein H1 (H) , heterogeneous nuclear ribonucleoprotein H2 (H') , heterogeneous nuclear ribonucleoprotein H1-like , heterogeneous nuclear ribonucleoprotein H-like , hnRNP H , ratsg1

GENE ID SPEZIES
3187 Homo sapiens
395157 Gallus gallus
432071 Xenopus laevis
446758 Xenopus laevis
448155 Xenopus (Silurana) tropicalis
462329 Pan troglodytes
481455 Canis lupus familiaris
541202 Bos taurus
100067495 Equus caballus
100341383 Oryctolagus cuniculus
100415060 Callithrix jacchus
100467241 Ailuropoda melanoleuca
100519535 Sus scrofa
100540708 Meleagris gallopavo
100606289 Nomascus leucogenys
59013 Mus musculus
140931 Rattus norvegicus
704469 Macaca mulatta
101122518 Ovis aries
100726512 Cavia porcellus
101683493 Mustela putorius furo
402984 Danio rerio
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