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HNRNPF belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). Zusätzlich bieten wir Ihnen HNRNPF Antikörper (80) und HNRNPF Kits (22) und viele weitere Produktgruppen zu diesem Protein an.
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hnRNP H (zeige HNRNPH1 Proteine)/F are important for maintenance and differentiation of embryonic stem cells and that this at least in part reflects a switch in TCF3 (zeige TCF3 Proteine) alternative splicing that leads to repression of CDH1/E-cadherin (zeige CDH1 Proteine).
Results from a study on gene expression variability markers in early-stage human embryos shows that HNRNPF is a putative marker for the 3-day, 8-cell embryo stage.
heterogeneous nuclear ribonucleoprotein F (hnRNPF) regulates G-quadruplex-associated alternative splicing across the transcriptome.
Simulation results demonstrate that the RNA binding domain qRRM2 of hnRNP F binds strongly with G-tract RNA, but any mutation of the G-tract leads to a drastic reduction of the binding free energy.
Human T2D kidneys exhibited more RPTC apoptosis and lower expression of hnRNP F, SIRTUIN-1, an (zeige SIRT1 Proteine)d FOXO3alpha than nondiabetic kidneys.
hnRNP F is a co-factor in a subset of tristetraprolin (zeige ZFP36 Proteine)/BRF1 (zeige ZFP36L1 Proteine)/BRF2 (zeige ZFP36L2 Proteine)-mediated mRNA decay.
These data point to a functional interaction between hnRNP F and SRSF1 (zeige SRSF1 Proteine) as a mutant that eliminates SRSF1 (zeige SRSF1 Proteine) binding to exon 11, or a SRSF1 (zeige SRSF1 Proteine) knockdown, which prevents the stimulatory effect of hnRNP F over expression.
this result suggests that hnRNP F directs formation of the exo (zeige ENOX2 Proteine)n 4 minus variant of ENOX2.
The study shows solution structures of the three quasi-RNA-recognition motifs of heterogeneous nuclear ribonucleoprotein F in complex with G-tract RNA.
heterogeneous ribonucleoprotein F is involved in the regulation of cell proliferation via the mammalian target of rapamycin (zeige FRAP1 Proteine)/S6 kinase 2 (zeige RPS6KB2 Proteine) pathway
hnRNP F protects kidneys against oxidative stress and nephropathy via stimulation of Sirtuin-1 (zeige SIRT1 Proteine) expression and signaling in diabetes.
the beneficial actions of insulin (zeige INS Proteine) in diabetic nephropathy appear to be mediated, in part, by suppressing renal Nrf2 (zeige NFE2L2 Proteine) and Agt (zeige AGXT Proteine) gene transcription and preventing Nrf2 (zeige NFE2L2 Proteine) stimulation of Agt (zeige AGXT Proteine) expression via hnRNP F/K.
These data demonstrate that hnRNP F stimulates Ace-2 (zeige ACE2 Proteine) gene transcription, prevents TGF-beta1 (zeige TGFB1 Proteine) inhibition of Ace-2 (zeige ACE2 Proteine) gene transcription and induction of kidney injury in diabetes.
genome wide analysis of splicing events and gene expression regulated by hnRNPH (zeige HNRNPH1 Proteine)/F in oligodendrocytes
These data suggest that hnRNP F plays a modulatory role and can ameliorate hypertension, renal hypertrophy, and interstitial fibrosis in diabetes.
The hnRNP F can function as repressors of MOR translation dependent on the M4 sequence.
define hnRNP F as a regulatory element of MBP (zeige MBP Proteine) expression in oligodendrocytes and imply an important function of hnRNP F in the control of myelin synthesis.
hnRNP F directs formation of the exon 4 minus variant of ENOX2 (zeige ENOX2 Proteine)
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified.
HnRNP F protein
, nucleolin-like protein mcs94-1
, heterogeneous nuclear ribonucleoprotein F
, heterogeneous nuclear ribonucleoprotein F-like
, hnRNP F
, ribonucleoprotein F
, heterogeneous nuclear ribonucleoprotein F-like protein
, heterogeneous nuclear ribonucleoprotein-like protein