Heterogeneous Nuclear Ribonucleoprotein D (AU-Rich Element RNA Binding Protein 1, 37kDa) Proteine (HNRNPD)

HNRNPD belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). Zusätzlich bieten wir Ihnen Heterogeneous Nuclear Ribonucleoprotein D (AU-Rich Element RNA Binding Protein 1, 37kDa) Antikörper (122) und Heterogeneous Nuclear Ribonucleoprotein D (AU-Rich Element RNA Binding Protein 1, 37kDa) Kits (15) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
HNRNPD 3184 Q14103
HNRNPD 79256 Q9JJ54
HNRNPD 11991 Q60668
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Top Heterogeneous Nuclear Ribonucleoprotein D (AU-Rich Element RNA Binding Protein 1, 37kDa) Proteine auf antikoerper-online.de

Showing 8 out of 11 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,370.21
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Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,370.21
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Escherichia coli (E. coli) Human GST tag 50 μg Anmelden zum Anzeigen 13 bis 16 Tage
$242.00
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
$888.80
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Escherichia coli (E. coli) Human GST tag 100 μg Anmelden zum Anzeigen 11 Days
$411.40
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Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$230.67
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Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Anmelden zum Anzeigen 11 Days
$291.50
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,960.83
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HNRNPD Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Rat (Rattus)

Mouse (Murine)

Weitere Proteine zu Heterogeneous Nuclear Ribonucleoprotein D (AU-Rich Element RNA Binding Protein 1, 37kDa) (HNRNPD) Interaktionspartnern

Human Heterogeneous Nuclear Ribonucleoprotein D (AU-Rich Element RNA Binding Protein 1, 37kDa) (HNRNPD) Interaktionspartner

  1. Anti-apoptotic gene Bcl-2 was suppressed by berberine treatment and lncRNA CASC2, inducing the pro-apoptotic effects. Moreover, lncRNA CASC2 binds to AUF1, which sequestered AUF1 from binding to Bcl-2 mRNA, thus inducing the inactivation of Bcl-2 translation.

  2. Study identified RANKL and BCL6 mRNA as targets of AUF1 p42. Detailed analysis of 3'UTRs revealed for both that full instability required two elements, which are conserved in evolution. In RANKL mRNA both elements are AU-rich and separated by 30 bases, while in BCL6 mRNA one is AU-rich and 60 bases from a non-AU-rich element that potentially forms a stem-loop structure.

  3. The work presented here addresses the mechanism of AUF1 inhibition of the replication of poliovirus and CVB3. We demonstrate that AUF1 knockdown in human cells results in increased viral translation, RNA synthesis, and virus production.

  4. The expression of AUF-1 was selectively decreased in the bronchial, but not in the bronchiolar, epithelium from patients with stable COPD compared to control smokers.

  5. Overexpression of AUF1 and HuR is a common finding observed in thyroid malignancy. Analysis of the tissues obtained by surgical resection as demonstrated in this study is comparable to a fine needle aspiration and in combination with AUF1/HuR immuno-analysis may support the conventional immunohistological investigations.

  6. Our study provides new insights into the regulation of APP pre-mRNA processing, supports the role for nELAVLs as neuron-specific splicing regulators and reveals a novel function of AUF1 in alternative splicing.

  7. Both hnRNP D and DL are able to control their own expression by alternative splicing of cassette exons in their 3'UTRs. Exon inclusion produces mRNAs degraded by nonsense-mediated decay. Moreover, hnRNP D and DL control the expression of one another by the same mechanism.

  8. Lnc_ASNR interacted with the protein ARE/poly (U)-binding/degradation factor 1(AUF1), which is reported to promote rapid degradation of the Bcl-2 mRNA, an inhibitor of apoptosis. Lnc_ASNR binds to AUFI in nucleus, decreasing the cytoplasmic proportion of AUF1 which targets the B-cell lymphoma-2 (Bcl-2) mRNA.

  9. in the present case, the identified mutations in HNRNPD and risk polymorphisms are plausible molecular players in the manifestation of CD.

  10. AUF1 p45 triggers the RNA switch in the flaviviral genome that is crucial for viral replication. These findings represent an important example of how cellular (host) factors promote the propagation of RNA viruses

  11. AUF1 might be a potential player in renal tubulointerstitial fibrosis through modulation of TGF-beta signal transduction via posttranscriptional regulation of Nedd4L.

  12. Results indicate that the IL-6/STAT3/NF-kappaB positive feedback loop includes AUF1 and is responsible for the sustained active status of cancer-associated fibroblasts.

  13. Depletion of AUF1 abolishes the global interaction of miRNAs and AGO2. AUF1 functions in promoting miRNA-mediated mRNA decay globally.

  14. High AUF1 expression is associated with esophageal squamous cell carcinoma.

  15. Arginine methylation improves the viral RNA chaperone activity of AUF1 p45.

  16. These results suggest that the post-transcriptional regulation of ATX expression by HuR and AUF1 modulates cancer cell migration.

  17. analysis of the effect of the N-terminal RNA recognition motif on AUF1

  18. We found a C-rich element (CRE) in mu-opioid receptor (MOR) 3'-untranslated region (UTR) to which poly (rC) binding protein 1 (PCBP1) binds, resulting in MOR mRNA stabilization. AUF1 phosphorylation also led to an increased interaction with PCBP1.

  19. Findings indicate that hnRNP D and arginine methylation play important roles in the regulation of Flt-1 mRNA alternative polyadenylation.

  20. hnRNPA2B1, hnRNPD, hnRNPL , and YBX1 might play important roles in gastric cancer tumorigenesis.

Mouse (Murine) Heterogeneous Nuclear Ribonucleoprotein D (AU-Rich Element RNA Binding Protein 1, 37kDa) (HNRNPD) Interaktionspartner

  1. Study identified RANKL and BCL6 mRNA as targets of AUF1 p42. Detailed analysis of 3'UTRs revealed for both that full instability required two elements, which are conserved in evolution. In RANKL mRNA both elements are AU-rich and separated by 30 bases, while in BCL6 mRNA one is AU-rich and 60 bases from a non-AU-rich element that potentially forms a stem-loop structure.

  2. Control of ARE-mRNA decay by AUF1 represents a mechanism for adult stem cell regulation.

  3. These results suggest that the post-transcriptional regulation of ATX expression by HuR and AUF1 modulates cancer cell migration.

  4. MEF2C is a key effector of the myogenesis program promoted by AUF1.

  5. hnRNP D is critically involved in LDLR mRNA degradation in liver tissue in vivo.

  6. This study showed that arginines in the RGG domain of AUF1 are methylated, and AUF1-RGG peptides may be novel reagents that reduce macrophage activation in inflammation.

  7. Mitochondrial biogenesis occurs in the presence of increased CUG-BP1 and AUF1, suggesting that reductions in known mRNA destabilizing proteins likely does not contribute to exercise-induced mitochondrial biogenesis.

  8. Data show that AUF1 binds and strongly activates the transcription promoter for telomerase catalytic subunit Tert.

  9. These findings demonstrate that AUF1 regulates VEGF expression, and this study identifies an RGG peptide that suppresses VEGF gene expression.

  10. 30-kDa protein is a novel isoform of AUF1 family and is the main component of the DAP-II complex that binds to the DAS sequence.

  11. p16( INK4a) is also a modulator of transcription and apoptosis through controlling the expression of two major transcription regulators, AUF1 and E2F1

  12. involved in splenic follicular B cell maintenance

  13. hnRNP D plays a role as a fine regulator contributing to the mcry1 mRNA turnover rate and the modulation of circadian rhythm.

  14. interaction with lactate dehydrogenase

  15. AUF1 p40, HuR, and the 3'UTR of the CTR mRNA transcript could be involved in posttranscriptional regulation of CTR mRNA expression.

  16. AUF1 cell cycle variations define genomic DNA methylation by regulation of DNMT1 mRNA stability

  17. These and other data describe a novel post-transcriptional mechanism whereby AUF1 acts as a crucial attenuator of the inflammatory response, promoting the rapid decay of selective proinflammatory cytokine mRNAs following endotoxin activation.

  18. AUF1 participates in mammary gland differentiation processes under the control of lactogenic hormone signals.

  19. Modulation of AUF1 and HuR by their overexpression or siRNA revealed that SPHK1 mRNA in v-Src- and mock-NIH3T3 was regulated reciprocally by these factors.

  20. Auf1/Hnrnpd-deficient mice develop pruritic inflammatory skin disease

Xenopus laevis Heterogeneous Nuclear Ribonucleoprotein D (AU-Rich Element RNA Binding Protein 1, 37kDa) (HNRNPD) Interaktionspartner

  1. These results show that ElrA and AUF1 bind to cyclin B2 mRNA independent of cytoplasmic polyadenylation elements and function by binding other elements.

Pig (Porcine) Heterogeneous Nuclear Ribonucleoprotein D (AU-Rich Element RNA Binding Protein 1, 37kDa) (HNRNPD) Interaktionspartner

  1. Concurrent binding and modifications of AUF1 and HuR mediate the pH-responsive stabilization of phosphoenolpyruvate carboxykinase mRNA in kidney cells.

  2. the renal proximal tubule, may require the remodeling of AUF1 binding to the elements that mediate the rapid turnover of PEPCK mRNA.

Heterogeneous Nuclear Ribonucleoprotein D (AU-Rich Element RNA Binding Protein 1, 37kDa) (HNRNPD) Protein Überblick

Protein Überblick

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.

Genbezeichner und Symbole assoziert mit HNRNPD

  • heterogeneous nuclear ribonucleoprotein D (HNRNPD)
  • heterogeneous nuclear ribonucleoprotein D (Hnrnpd)
  • heterogeneous nuclear ribonucleoprotein D (hnrnpd)
  • heterogeneous nuclear ribonucleoprotein D L homeolog (hnrnpd.L)
  • Auf1 Protein
  • auf1a Protein
  • C230004L04 Protein
  • HNRNPD Protein
  • hnrnpd0 Protein
  • Hnrpd Protein
  • p37 Protein
  • wu:fa28b06 Protein
  • zgc:162951 Protein

Bezeichner auf Proteinebene für HNRNPD

ARE-binding protein AUFI, type A , heterogeneous nuclear ribonucleoprotein D0 , hnRNP D0 , AU-rich element RNA-binding factor 1 , AU-rich element RNA-binding protein 1 , RNA binding protein p45AUF1 , heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) , AUF1 , p37 AUF1 , RNA binding protein

GENE ID SPEZIES
3184 Homo sapiens
79256 Rattus norvegicus
422602 Gallus gallus
527471 Bos taurus
461216 Pan troglodytes
478450 Canis lupus familiaris
594903 Xenopus (Silurana) tropicalis
100294646 Ovis aries
11991 Mus musculus
496375 Xenopus laevis
560522 Danio rerio
100512244 Sus scrofa
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