anti-Hes Family bHLH Transcription Factor 1 (HES1) Antikörper

This protein belongs to the basic helix-loop-helix family of transcription factors. Zusätzlich bieten wir Ihnen HES1 Kits (16) und HES1 Proteine (13) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
HES1 3280 Q14469
HES1 15205 P35428
HES1 29577 Q04666
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Top anti-HES1 Antikörper auf antikoerper-online.de

Showing 10 out of 164 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IF, IP, IHC, WB WB Suggested Anti-HES1 Antibody Titration:  1.25ug/ml  Positive Control:  Raji cell lysate HES1 is strongly supported by BioGPS gene expression data to be expressed in Human Raji cells 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-Hes1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:12500  Positive Control:  Rat Kidney WB Suggested Anti-Hes1 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:12500 <br /> Positive Control: Rat Kidney 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Maus Unkonjugiert ChIP, ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: HES-1 Antibody (4H1) [NBP1-47791] - Staining of paraffin-embedded endometrium using anti-Hes1 mouse monoclonal antibody. Immunohistochemistry-Paraffin: HES-1 Antibody (4H1) [NBP1-47791] - Staining of paraffin-embedded Carcinoma of liver using anti-Hes1 mouse monoclonal antibody. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$585.06
Details
Ratte Kaninchen Unkonjugiert WB Anti-Hes1 antibody, Western blotting WB: Rat Kidney Tissue Lysate Anti-Hes1 antibody, Western blottingWB: Rat Kidney Tissue Lysate 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert WB HES1 Antibody (N-term) (ABIN657944) western blot analysis in U251 cell line lysates (35 µg/lane). This demonstrates the HES1 antibody detected the HES1 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IP, WB Western Blot: HES-1 Antibody [NBP1-30912] - PC-12 whole cell extract.12 % SDS-PAGE HES1 antibody [N1], N-term dilution: 1:1000 Western Blot: HES-1 Antibody [NBP1-30912] - Sample(30 ug whole cell lysate)A:A431 12% SDS PAGE, antibody diluted at 1:1000. 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$514.63
Details
Human Maus Unkonjugiert IF, IHC, IHC (p), WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Kaninchen Unkonjugiert FACS, IF, WB Western blot analysis of anti-HES1 Antibody (N-term T24) (ABIN390222) in HL60 cell line lysates (35 µg/lane). HES1 (arrow) was detected using the purified polyclonal antibody (1:60 dilution). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Maus Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human kidney tissue labeled with Anti-HES-1 Polyclonal Antibody, Unconjugated (ABIN682393) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat brain labeled with Anti-HES1 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$318.45
Details
Fledermaus Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details

HES1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-HES1 Antikörper

  1. Cow (Bovine) Polyclonal HES1 Primary Antibody für IF, IP - ABIN2779597 : Hoebeke, De Smedt, Van de Walle, Reynvoet, De Smet, Plum, Leclercq: Overexpression of HES-1 is not sufficient to impose T-cell differentiation on human hematopoietic stem cells. in Blood 2006 (PubMed)
    Show all 12 Pubmed References

  2. Human Monoclonal HES1 Primary Antibody für ChIP, ICC - ABIN4317125 : Wang, Wei, Han, Sato, Ghanbari-Azarnier, Whetstone, Poon, Hu, Zheng, Zhang, Wang, Wunder, Alman: Hedgehog and Notch signaling regulate self-renewal of undifferentiated pleomorphic sarcomas. in Cancer research 2012 (PubMed)
    Show all 5 Pubmed References

  3. Mouse (Murine) Polyclonal HES1 Primary Antibody für IF (p), IHC (p) - ABIN682393 : Long, Qiu, Liu, Fei, Feng, Wang, Zhong, Yi, Liu, Zhang, Han: Functional recovery and neuronal regeneration of a rat model of epilepsy by transplantation of Hes1-down regulated bone marrow stromal cells. in Neuroscience 2012 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal HES1 Primary Antibody für ICC, IF - ABIN440957 : Kang, Yang, Xiao, Guo, Guo, Yan, Qi, Wang, Ryffel, Li, Deng: Osteoblast Hypoxia-Inducible Factor-1α Pathway Activation Restrains Osteoclastogenesisviathe Interleukin-33-MicroRNA-34a-Notch1 Pathway. in Frontiers in immunology 1970 (PubMed)

Weitere Antikörper gegen HES1 Interaktionspartner

Human Hes Family bHLH Transcription Factor 1 (HES1) Interaktionspartner

  1. In the present study, the authors reported the first observation of Hes1 oscillatory expression in human neural progenitor /stem cells, with an approximately 1.5 hour periodicity and a Hes1 protein half-life of about 17 (17.6 +/- 0.2) minutes. Human cytomegalovirus infection disrupts the Hes1 rhythm and down-regulates its expression.

  2. A three-molecule score based on the expression of Notch (zeige NOTCH1 Antikörper) pathway molecules: Jagged1 (zeige JAG1 Antikörper), intracellular Notch1 (zeige NOTCH1 Antikörper) (ICN1) and Hes1 (JIH score) to assess prognostic value in non-metastasis clear cell renal cell carcinoma (zeige MOK Antikörper) (ccRCC).

  3. we demonstrate for the first time an essential role of HPV oncoprotein E6 that selectively overexpresses in CaCxSLCs and participates in maintenance of stem cell phenotype and stemness through upregulation of Hes1 while preponderance of E7 leads to differentiation.

  4. IE1 is involved in Hes1 degradation by assembling a ubiquitination complex and promoting Hes1 ubiquitination as a potential E3 ubiquitin ligase (zeige MUL1 Antikörper), followed by proteasomal degradation of Hes1.

  5. Notch (zeige NOTCH1 Antikörper) signaling and Id2/3 regulate neurogenesis in a complementary manner and ID factors can induce neural stem cell maintenance and quiescence in the absence of Notch (zeige NOTCH1 Antikörper).

  6. The phenotype was rescued by ectopic expression of miRNA182-5p in Delta182 cells. A bioinformatic analysis and Hes1 modulation data suggested that Hes1 could be a putative target of miRNA182-5p. A reciprocal relationship between miRNA182-5p and Hes1 was seen in the context of TK inhibition

  7. These results suggest that HES1 promotes extracellular matrix protein expression and inhibits proliferative and migratory functions in the trabecular meshwork cells under oxidative stress, thereby providing a novel pathogenic mechanism underlying and a potential therapeutic target to primary open-angle glaucoma

  8. Hes1 disruption leads to tumor regression without perturbing normal stem cell homeostasis, preclinically validating Hes1 as a cancer therapeutic target.

  9. Low Hes1 expression is associated with left ventricle hypertrabeculation/non-compaction and Menetrier-like gastropathy.

  10. GPR146 (zeige GPR146 Antikörper) has an antiviral role in fighting against viral infection, although the GPR146 (zeige GPR146 Antikörper)-mediated protection is eliminated by IRF3 (zeige IRF3 Antikörper)/HES1-signalling.

Mouse (Murine) Hes Family bHLH Transcription Factor 1 (HES1) Interaktionspartner

  1. These results suggest that hyperhomocysteinemia-enhanced brain damage is associated with increased autophagy and neuronal apoptosis in Apo E (zeige APOE Antikörper)(-/-) mice, in which downregulation of hes1 and hes5 (zeige HES5 Antikörper) is involved.

  2. Although Hes5 (zeige HES5 Antikörper)-GFP and Hes1 are coexpressed in particular developmental contexts, we also noted cohorts of lens or retinal cells expressing just one factor. The dynamic Hes5 (zeige HES5 Antikörper)-GFP expression pattern, coupled with its derepressed expression in Hes1 mutants, suggests that this transgene contains the relevant cis (zeige CISH Antikörper)-regulatory elements that regulate endogenous Hes5 (zeige HES5 Antikörper) in the mouse lens and retina.

  3. there is a link between Dmrta2 (zeige DMRTA2 Antikörper) modulation of Hes1 expression and the maintenance of neural progenitor cells during cortical development

  4. Hes-1 expression is maintained in neural progenitor territory throughout mouse neocortical development, a simple shift from Notch (zeige NOTCH1 Antikörper)-independent to -dependent state makes it pleiotropic as the former maintains the neural stem cells in a non-dividing/slow-dividing state, whereas the latter is very much required for maintenance and proliferation of radial glial cells.

  5. inhibition of PTEN by Notch1 (zeige NOTCH1 Antikörper)/Hes1 in response to high glucose concentration inhibits autophagy, which is associated with the progression of fibrosis in diabetic nephropathy

  6. this paper shows the critical role of the Notch1 (zeige NOTCH1 Antikörper)-Hes1 signaling cascade in the regulation of innate immunity in acetaminophen-triggered liver inflammation

  7. results suggest that SCF (zeige KITLG Antikörper)(FBXL14 (zeige FBXL14 Antikörper)) promotes neuronal differentiation by targeting HES1 for ubiquitin-dependent proteolysis and that the C-terminal WRPW motif in HES1 is required for this process

  8. Notch (zeige NOTCH1 Antikörper) signaling and Id2/3 regulate neurogenesis in a complementary manner and ID factors can induce neural stem cell maintenance and quiescence in the absence of Notch (zeige NOTCH1 Antikörper).

  9. that HIF-1alpha (zeige HIF1A Antikörper) but not HIF-2alpha (zeige EPAS1 Antikörper) is able to interact with either GA-binding protein alpha or GA-binding protein beta1

  10. Hes1 disruption leads to tumor regression without perturbing normal stem cell homeostasis, preclinically validating Hes1 as a cancer therapeutic target.

Pig (Porcine) Hes Family bHLH Transcription Factor 1 (HES1) Interaktionspartner

  1. study identified nucleolar complex protein 3 homolog(FAD24 (zeige NOC3L Antikörper)) as a novel downstream target of transcription factor HES1 during adipogenesis

HES1 Antigen-Profil

Protein Überblick

This protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box.

Genbezeichner und Symbole assoziert mit HES1

  • hes family bHLH transcription factor 1 (HES1) Antikörper
  • hairy and enhancer of split 1 (Drosophila) (Hes1) Antikörper
  • hes family bHLH transcription factor 1 (Hes1) Antikörper
  • hes family bHLH transcription factor 4 (HES4) Antikörper
  • hes family bHLH transcription factor 1 L homeolog (hes1.L) Antikörper
  • bHLHb39 Antikörper
  • c-hairy1A Antikörper
  • HAIRY1 Antikörper
  • HES-1 Antikörper
  • hes1 Antikörper
  • HHL Antikörper
  • Hry Antikörper
  • Xhairy-1 Antikörper
  • Xhairy1 Antikörper
  • Xlh1 Antikörper

Bezeichner auf Proteinebene für HES1

class B basic helix-loop-helix protein 39 , hairy homolog , hairy-like protein , transcription factor HES-1 , RHL , C-HAIRY1 , c-hairy1B , Hairy and enhancer of split 1-A , Protein hairy-1 , hairy1 , transcription factor HES-1-A , hairy and enhancer of split 1 , LOW QUALITY PROTEIN: transcription factor HES-1

GENE ID SPEZIES
3280 Homo sapiens
539547 Bos taurus
15205 Mus musculus
29577 Rattus norvegicus
395128 Gallus gallus
100499567 Sus scrofa
397813 Xenopus laevis
100734567 Cavia porcellus
101106560 Ovis aries musimon
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