Hemoglobin, gamma G Proteine (HBG2)

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Zusätzlich bieten wir Ihnen HBG2 Kits (29) und HBG2 Antikörper (22) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
HBG2 3048 P69892
HBG2 736917 P61920
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Top HBG2 Proteine auf antikoerper-online.de

Showing 6 out of 8 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
Hefe Schimpanse His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Hefe REACT_Capuchin Monkey His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Hefe Pongo pygmaeus His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage

HBG2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
Capuchin Monkey (Cebus)


Weitere Proteine zu Hemoglobin, gamma G (HBG2) Interaktionspartnern

Human Hemoglobin, gamma G (HBG2) Interaktionspartner

  1. Genetic association studies provide a rationale for functional studies of HBG2 expression in wild-type and T/A/T haplotype erythroblasts and mechanistic studies like chromatin conformation capture experiments, to evaluate the role of chromatin looping as a mediator of the T/A/T haplotype effects on HbF.

  2. In Portuguese beta-thalassemia carriers the HBG2 XmnI polymorphism is strongly associated with HbF levels.

  3. DNA polymorphisms at BCL11A, HBS1L-MYB and Xmn1-HBG2 site loci associated with fetal hemoglobin levels in sickle cell anemia patients from Northern Brazil.

  4. Its polymorphism effects HbF, HbE (zeige HBe1 Proteine), MCV and MCH (zeige PMCH Proteine) levels in Thai HbE (zeige HBe1 Proteine) carriers.

  5. Data indicate that the T to A conversion results in a leucine to histidine amino acid change at codon 105 of the (G)gamma-globin HBG2 gene and caused a hemoglobin (Hb) variant with lowered oxygen affinity.

  6. Hemoglobin gamma G plays a role in modifying clinical symptoms of beta-thalassemia innorthern Thailand.

  7. Data suggest that segregation of BCL11A (zeige BCL11A Proteine) haplotype 2 indicating an involvement of this locus in Hb F expression.

  8. Hb F is regulated in inherited bone marrow failure syndromes by Xmn1-HBG2, as it is in the haemoglobinopathies.

  9. Our data suggest that a temporal repression mechanism is operative in the silencing of gamma-globin gene expression

  10. results establish SATB2 as a novel gamma-globin gene regulator and provide a glimpse of the differential and cooperative roles of SATB family proteins in modulating clustered genes transcription

HBG2 Protein Überblick

Protein Überblick

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Genbezeichner und Symbole assoziert mit Hemoglobin, gamma G Proteine (HBG2)

  • hemoglobin subunit gamma 2 (HBG2)
  • hemoglobin subunit gamma 2 (hbg2)
  • hemoglobin subunit gamma 2 L homeolog (hbg2.L)
  • hemoglobin, gamma G (HBG1)
  • hbb2 Protein
  • HBG1 Protein
  • HBG2 Protein
  • MGC88976 Protein
  • TNCY Protein

Bezeichner auf Proteinebene für Hemoglobin, gamma G Proteine (HBG2)

G-gamma globin Paulinia , abnormal hemoglobin , gamma-2-globin , hb F Ggamma , hemoglobin gamma-2 chain , hemoglobin gamma-G chain , hemoglobin subunit gamma-2 , methemoglobin , hemoglobin, gamma G , gamma-2 globin , Hemoglobin subunit gamma-1

3048 Homo sapiens
448249 Xenopus (Silurana) tropicalis
100381042 Xenopus laevis
736917 Pan troglodytes
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