Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Zusätzlich bieten wir Ihnen HSP90AA2 Antikörper (212) und viele weitere Produktgruppen zu diesem Protein an.
Showing 5 out of 6 products:
Human HSP90AA2 Protein expressed in Escherichia coli (E. coli) - ABIN1686664
Arlander, Eapen, Vroman, McDonald, Toft, Karnitz: Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress. in The Journal of biological chemistry 2003
Show all 10 Pubmed References
Knocking out Hsp90beta (zeige HSP90AB1 Proteine) leads to tumour cell death. Extracellular supplementation with recombinant Hsp90alpha, but not Hsp90beta (zeige HSP90AB1 Proteine), protein recovers tumourigenicity of the Hsp90alpha-knockout cells. Sequential mutagenesis identifies two evolutionarily conserved lysine residues, lys (zeige LYZ Proteine)-270 and lys (zeige LYZ Proteine)-277, in the Hsp90alpha subfamily that determine the extracellular Hsp90alpha function.
We revealed that Hsp90A (zeige HSP90AA1 Proteine) and Hsp90B (zeige HSP90AB1 Proteine) are partly colocalized with heparan sulfate proteoglycans (HSPGs) on the cell surface and that this colocalization was sensitive to heparin.
Heat shock protein 90 stimulates rat mesenchymal stem cell migration via PI3K/Akt and ERK1/2 pathways
Studied the serum prolactin (zeige PRL Proteine), cortisol, and ACTH (zeige POMC Proteine) stress response of intensive care unit (ICU) patients with severe sepsis/septic shock (SS) or systemic inflammatory response syndrome (SIRS) compared to healthy subjects.
These results indicate that cytoplasmic HSP90alpha may serve as a biomarker for perineural invasion in pancreatic cancer
Increased expression of nucleated RBC (zeige CACNA1C Proteine), HSP90alpha and corresponding decreased expression of HO-2 (zeige HMOX2 Proteine) in such hypoxic condition may play a protective role; to prevent cord blood RBC (zeige CACNA1C Proteine) against stress induced damage during preeclampsia.
STAT5b (zeige STAT5B Proteine) pathway regulates Hsp90alpha expression under hypoxic conditions
HSP90alpha was an IMH-2 epitope-associated protein. Tumor HSP90alpha overexpression was correlated with the metastasis and poor prognosis of colorectal cancer patients.
extracellular HSP90alpha transactivates EGFR/ErbB1 (zeige EGFR Proteine) through TLR4 (zeige TLR4 Proteine) and a PKCdelta (zeige PKCd Proteine)/c-Src (zeige SRC Proteine) pathway, which induces ATP release and cytosolic Ca(2 (zeige CA2 Proteine)+) increase and finally favors glioblastoma cell migration.
High gene expression of Hsp90 alpha (zeige HSP90AA1 Proteine) is associated with leukemia.
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity). Plays a key role in slow and fast muscle development in the embryo. Plays a role in myosin expression and assembly.