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heat shock protein; may have an important role following forebrain ischemia and may allow astrocytes to protect neurons. Zusätzlich bieten wir Ihnen Heat Shock 70kDa Protein 4 Kits (22) und Heat Shock 70kDa Protein 4 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.
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Dog (Canine) Monoclonal HSPA4 Primary Antibody für IF, IP - ABIN968012
Lee-Yoon, Easton, Murawski, Burd, Subjeck: Identification of a major subfamily of large hsp70-like proteins through the cloning of the mammalian 110-kDa heat shock protein. in The Journal of biological chemistry 1995
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Dog (Canine) Monoclonal HSPA4 Primary Antibody für IF, IP - ABIN968011
Moore, Scheinman, Bellgrau: The identification of a novel T cell activation state controlled by a diabetogenic gene. in Journal of immunology (Baltimore, Md. : 1950) 2001
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Cow (Bovine) Polyclonal HSPA4 Primary Antibody für IHC, WB - ABIN863194
Dragovic, Broadley, Shomura, Bracher, Hartl: Molecular chaperones of the Hsp110 family act as nucleotide exchange factors of Hsp70s. in The EMBO journal 2006
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Human Polyclonal HSPA4 Primary Antibody für ICC, IF - ABIN4320580
Morisaki, Yashiro, Kakehashi, Inagaki, Kinoshita, Fukuoka, Kasashima, Masuda, Sakurai, Kubo, Muguruma, Ohira, Wanibuchi, Hirakawa: Comparative proteomics analysis of gastric cancer stem cells. in PLoS ONE 2014
This review article documents reduced levels of mature miR (zeige MLXIP Antikörper)-23a in various tumors, primarily due to epigenetic silencing or alterations in biogenesis pathways. Moreover, inhibition of miR (zeige MLXIP Antikörper)-23a in stressed cells represent a general mechanism for inducing apoptosis and these microRNAs are showed to be regulated by molecular chaperon HSP70 (zeige HSP70 Antikörper)
High Hsp70 (zeige HSP70 Antikörper) and Hsp90 (zeige HSP90 Antikörper) expression was associated with worse overall survival and disease-free survival [review and meta-analysis]
The level of Hsp70 (zeige HSP70 Antikörper) was higher in the allergic rhinitis (AR) group compared with the non-AR group. Furthermore, treatment of HNE (zeige ELANE Antikörper) cells with Th2 cytokines induced secretion of Hsp70 (zeige HSP70 Antikörper) into the extracellular area, and did not influence the production of Hsp70 (zeige HSP70 Antikörper). These results suggest that Hsp70 (zeige HSP70 Antikörper) may play a major role in the pathogenesis of AR.
The article results indicate that the heat-shock protein HSP70 (zeige HSP70 Antikörper)-2 (zeige HSPA1B Antikörper) (+1538 A/G) and HSP70-hom (zeige HSPA1L Antikörper) (+2437 C/T) SNPs are highly associated with renal complications in Type 2 Diabetes Mellitus among the South Indian population.
HSP70 (zeige HSP70 Antikörper)-Hrd1 (zeige SYVN1 Antikörper) axis represents a potential therapeutic target for restoring the oncorepressor activity of unstable lymphoma-associated Blimp-1 (zeige PRDM1 Antikörper) mutants.
verified the interaction of cellular chaperon HSP70 (zeige HSP70 Antikörper) with Porcine reproductive and respiratory syndrome virus NSP12, and demonstrated that NSP12 could recruit HSP70 (zeige HSP70 Antikörper) to maintain its own stability and benefit for the virus replication
Modulatory action of extracellular HSP70 (zeige HSP70 Antikörper) on A549 inflammatory response through RAGE (zeige AGER Antikörper) was able to evoke important expression changes in monocyte, showing its relevance in influencing the interaction between cancer and immune system cell.
Here the authors show that in budding yeast, Hsf1 (zeige HSF1 Antikörper) basally associates with the chaperone Hsp70 (zeige HSP70 Antikörper) and this association is transiently disrupted by heat shock, providing the first evidence that a chaperone repressor directly regulates Hsf1 (zeige HSF1 Antikörper) activity.
Pharmacological or genetic activation of heat shock protein 70 (Hsp70 (zeige HSP70 Antikörper)) protects against loss of parkin (zeige PARK2 Antikörper) Function. Heat shock protein members may act as compensatory factors for parkin (zeige PARK2 Antikörper) loss of function and that the exploitation of these factors may be of potential therapeutic value.
targeting the Hsp70 (zeige HSP70 Antikörper) induction in Hsp90 (zeige HSP90 Antikörper) inhibitor-treated cancer cells and tumor vasculature cells may beneficially enhance the radiosensitizing effect
Data show that heat shock protein 70 (HSP70 (zeige HSP70 Antikörper)) induction by geranylgeranylacetone (GGA) was effective against N-methyl-N-nitrosourea (MNU-induced photoreceptor cell loss.
Upregulation of HSPA4 would control apoptosis of inflammatory cells and immune response in the gut (zeige GUSB Antikörper), which might develop treatment resistance in inflammatory bowel disease.
regulates the expression of SDF-1 (zeige CXCL12 Antikörper) and Twist in fibroblasts, thereby controlling gastric ulcer healing
Inhibition of Apg-2 by shRNA not only decreased cell proliferation, but also induced cell apoptosis in BCR/ABL (zeige ABL1 Antikörper) positive chronic myeloid leukemia (zeige BCL11A Antikörper) cells (BaF3-BCR/ABL (zeige ABL1 Antikörper), BaF3-BCR/ABL (zeige ABL1 Antikörper)(T315I)).
PSMB8 (zeige PSMB8 Antikörper), ALDH1A1 (zeige ALDH1A1 Antikörper), and HSPA4 were identified to be located in ovarian tissues, to regulate 12 cellular pathways, and demonstrate age-dependent dynamic changes in expression profiling.
HSPA4L (zeige HSPA4L Antikörper) and HSPA4 collaborate in embryonic lung maturation, which is necessary for adaptation to air breathing at birth.
study demonstrates that lack of HSPA4 leads to cardiac hypertrophy and fibrosis; data reveal the distinct, non-redundant role of HSPA4 in the protein quality control that maintains the proper protein folding and homeostasis in cardiomyocytes
Data suggest HSPA4 is required for spermatogenesis. All homozygous HSPA4-deficient mice are apparently healthy; HSPA4 is expressed as early as E13.5 in male gonad; increased number of HSPA4-deficient males are infertile, whereas females are fertile.
Findings provide in vivo evidence that Hsp110 (zeige HSPH1 Antikörper) plays a critical function in tau phosphorylation state through maintenance of efficient PP2A (zeige PPP2R2B Antikörper) activity, confirming its role in pathogenesis of Alzheimer's disease and other tauopathies.
Overexpression of Apg-2 in proB-BCR/ABL (zeige ABL1 Antikörper) cells increases cell proliferation and protects cells from oxidative damage.
Expression of hspa4a and hspa4b are up-regulated in the inflamed gut (zeige GUSB Antikörper) in a manner similar to that previously observed in mammals.
heat shock protein\; may have an important role following forebrain ischemia and may allow astrocytes to protect neurons
heat shock 70 kDa protein 4
, heat shock 70-related protein APG-2
, heat shock 70kD protein 4
, heat shock protein, 110 kDa
, hsp70 RY
, heat shock protein Apg-2
, ischemia responsive 94 kDa protein
, heat shock protein 4